Results 11 to 20 of about 11,680 (228)

Use of Acitretin Among Girls and Women of Childbearing Age and Occurrence of Acitretin-Exposed Pregnancies in Germany [PDF]

Clinical drug investigation, 2023
Background and Objective Acitretin has long-lasting teratogenic properties. Therefore, pregnancies must be avoided during and within 3 years after acitretin treatment.
Jonas Reinold, B. Kollhorst, Hellen L. Temme, Nadine Wentzell, Ulrike Haug   +4 more
semanticscholar   +2 more sources

The effects of acitretin on insulin resistance, glucose metabolism, and lipid levels in patients with psoriasis

Indian Journal of Dermatology, 2022
Context: Acitretin increases serum lipids. Data on its effects on insulin resistance and glucose metabolism are sparse and contradicting. Aims: The aim of this study is to investigate the effects of acitretin on insulin resistance, glucose metabolism ...
Satnam Singh Sachdev, Adawiyah Jamil, Preamala Gunabalasingam, Najeeb Ahmad Safdar   +3 more
doaj   +2 more sources

Acitretin in pediatric dermatoses

Indian Journal of Paediatric Dermatology, 2016
Acitretin, a synthetic retinoid and the active metabolite of etretinate has been increasingly used over the past two decades. It has proved effective in the treatment of many conditions associated with hyperkeratosis and dyskeratosis.
Manjyot Gautam, Harsh Tahiliani, Nitin Nadkarni, Sharmila Patil, Kiran Godse   +4 more
doaj   +2 more sources

The Inflammatory Factor SNP May Serve as a Promising Biomarker for Acitretin to Alleviate Secondary Failure of Response to TNF-a Monoclonal Antibodies in Psoriasis

Frontiers in Pharmacology, 2022
Psoriasis is a common immune-mediated inflammatory skin disease. Although biological agents have achieved good clinical efficacy in the treatment of moderate-to-severe psoriasis, the phenomenon of secondary non-response (SNR) has been gradually ...
Lanmei Lin, Yilun Wang, Xiaonian Lu, Tianxiao Wang, Qunyi Li, Runnan Wang, Jinfeng Wu, Jinhua Xu, Juan Du   +8 more
doaj   +2 more sources

HLA-DQA1 and DQB1 Alleles are Associated with Acitretin Response in Patients with Psoriasis

Frontiers in Bioscience-Landmark, 2022
Background: Psoriasis vulgaris is an immune-mediated inflammatory skin disease. Although the pathogenesis of psoriasis is unclear, genetic susceptibility, such as HLA-C*06:02, is believed to be a major risk factor.
Xingchen Zhou, Yijing He, Yehong Kuang, Wangqing Chen, Wu Zhu   +4 more
doaj   +2 more sources

Protective effects of melatonin and naringenin against acitretin induced hepatotoxicity via modulation of oxidative stress and inflammatory signaling

Scientific Reports
Drug-induced liver injury (DILI) represents a major clinical challenge, often limiting the therapeutic use of agents such as acitretin, a second-generation retinoid prescribed for psoriasis.
Samia S. Sokar, Sally E. Abu-Risha, Mahmoud Abdelrahman Alkabbani, Laila A. Ramadan, Alaa E. Elsisi   +4 more
doaj   +2 more sources

Efficacy and Safety of Tripterygium Wilfordii Glycoside Tablets Combined with Acitretin Capsules in the Treatment of Moderate to Severe Plaque Psoriasis: A Randomized Controlled Trial

Applied Bionics and Biomechanics, 2022
Objective. To probe into the clinical efficacy of tripterygium wilfordii glycoside (TWGs) tablets combined with acitretin capsules in the treatment of patients with moderate to severe plaque psoriasis (MSPP). Methods.
Qinghui Fu, Yunjie Zhu, Yiqi Fang, Changbo Dai   +3 more
doaj   +2 more sources

Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling

Saudi Pharmaceutical Journal, 2017
Acitretin has been a valuable option for the treatment of psoriasis, however, the molecular events of acitretin leading to the normalization of keratinocytes differentiation on psoriasis patients have not been fully explored. To investigate whether there
Xuan Qin, Chunna Chen, Yuan Zhang, Li Zhang, Yijie Mei, Xinchun Long, Rui Tan, Wenli Liang, Ledong Sun   +8 more
doaj   +2 more sources

Case Report: Successful Treatment of Cutaneous Squamous Cell Carcinoma in Three Patients With a Combination of Acitretin and Clarithromycin

Frontiers in Oncology, 2021
Few studies have evaluated acitretin as a primary treatment for cutaneous squamous cell carcinoma (CSCC). We report, for the first time, three cases of CSCC successfully treated with acitretin and clarithromycin.
Yan Zhao, Yanting Zhu, Haiqing Wang, Chao Ji   +3 more
doaj   +2 more sources

Severe and Prolonged Liver Damage in Pityriasis Rubra Pilaris Treated with acitretin: a Case Report

SN Comprehensive Clinical Medicine, 2022
Acitretin is a systemic retinoid that is used in dermatology for treatment of various inflammatory and especially hyperkeratotic diseases. Elevation of liver enzymes may occur occasionally but normally resolves spontaneously, at the latest after ...
Katrin Rak, H. Hamm, A. Kerstan, A. Kolb-Mäurer, M. Goebeler   +4 more
semanticscholar   +2 more sources