Results 91 to 100 of about 1,289 (149)

Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2019
In experimental obesity, the hypothalamus is affected by an inflammatory response activated by dietary saturated fats. This inflammation is triggered as early as one day after exposure to a high-fat diet, and during its progression, there is recruitment of inflammatory cells from the systemic circulation.
Fioravante, Milena   +12 more
openaire   +2 more sources

Investigating the role of Atypical Chemokine Receptor 3 in cancer development [PDF]

open access: yes, 2020
Atypical Chemokine Receptor 3 (ACKR3) is a seven-transmembrane spanning receptor with pleiotropic functions in development, homeostasis and pathophysiology.
Karatza, Angeliki
core  

ANALYSIS OF BIASED SIGNALING IN THE CHEMOKINE SYSTEM [PDF]

open access: yes, 2016
Chemokines constitute a family of almost 50 small secreted cytokines, recognized by about 20 different 7TM spanning G protein coupled receptors (GPCRs), that activating pertussis toxin sensitive G proteins induce cell migration.
A. Vacchini
core   +1 more source

Mechanism exploration and biomarker identification of glycemic deterioration in patients with diseases of the exocrine pancreas

open access: yesScientific Reports
The damage to the endocrine pancreas among patients with diseases of the exocrine pancreas (DP) leads to reduced glycemic deterioration, ultimately resulting in diabetes of the exocrine pancreas (DEP).
Zhen Wang   +10 more
doaj   +1 more source

O receptor atípico de quimiocinas ACKR2 exerce papel protetor na ascaridíase larval por Ascaris suum em modelo murino [PDF]

open access: yes, 2017
Human ascariasis is a highly prevalent geohelmintosis and affects millions of people worldwide and is associated with significant morbidity. This helminthiasis is related to precarious conditions of basic sanitation in addition to reduced socioeconomic ...
Renata Barbosa Peixoto
core  

The role of ACKR2 in inflammatory pathologies [PDF]

open access: yes, 2015
Chemokines are a highly conserved family of chemoattractant cytokines that are key to the movement of cells around the body under both inflammatory and homeostatic conditions. Chemokines bind to seven transmembrane G protein coupled receptors that signal
Pallas, Kenneth James
core   +1 more source

The role and regulation of the atypical chemokine receptor 2 in psoriasiform inflammation [PDF]

open access: yes, 2017
Psoriasis is a common, debilitating systemic inflammatory disorder that is characterised by sharply demarcated, thick, erythematous scaly skin plaques.
Shams, Kave
core  

The link between serum ACKR2 level and Crohn's Disease and its activity

open access: yesJournal of Surgery and Medicine, 2021
EKMEN, NERGİZ   +5 more
openaire   +3 more sources

Down regulation of estrogen receptors (ER; ER) and atypical chemokine receptors (ACKR 2; ACKR3; ACKR4) to increase 17β-estradiol (E2) levels in MCF-7 in-vitro study

open access: yesBasic & Clinical Cancer Research
Background: Oestrogen plays a vital role in breast development and is strongly related to breast cancer. This research article delves into this paradox.
Shruti Talashi
doaj  

Home - About - Disclaimer - Privacy