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International Immunopharmacology
This study aimed to explore the potential bind of Receptor Activity-Modifying Protein 3 (RAMP3) with atypical chemokine receptor 2 (ACKR2), and their cooperative regulation on the degradation of the immunosuppressive chemokine CCL2 in the tumor microenvironment of HCC.
Lan, Yang +3 more
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This study aimed to explore the potential bind of Receptor Activity-Modifying Protein 3 (RAMP3) with atypical chemokine receptor 2 (ACKR2), and their cooperative regulation on the degradation of the immunosuppressive chemokine CCL2 in the tumor microenvironment of HCC.
Lan, Yang +3 more
openaire +2 more sources
The link between serum ACKR2 level and Crohn's Disease and its activity
2021Backgrounds/Aim: Atypical chemokine receptor (ACKR) family suppresses chemokine response and keeps the inflammatory state under control. This study investigated ACKR2 serum levels, which are thought to have an effect on the extreme inflammatory state in Crohn's disease (CD).Methods: Active and newly diagnosed Crohn's patients under treatment ...
ÇİFÇİ, Sami +5 more
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IMPORTANCE OF ACKR2 GENE EXPRESSION IN THE EVALUATION OF MULTIPLE SCLEROSIS DISEASE
Direct interactions between cells, such as those between the cell and the extracellular matrix, are extremely important for the development and function of multicellular organisms. Since peptide hormones, neuropeptides and growth factors do not have the ability to cross the plasma membrane of their target cells like cytokines, they bind to receptors onopenaire +1 more source