Results 61 to 70 of about 1,254 (143)
Clinical and Translational Medicine, Volume 15, Issue 4, April 2025.Single‐cell analysis identifies transitional CXCL14+ myofibroblastic cancer‐associated fibroblasts (myCAFs) predominantly exist in the advanced‐stage lung adenocarcinoma (LUAD). Transitional CXCL14+ myCAFs fuel metastasis by promoting epithelial–mesenchymal transition (EMT) and angiogenesis on the spatial level.
Weijiao Xu +16 more
wiley +1 more source
Transcriptomic and Histological Characterization of Telocytes in the Human Dorsal Root Ganglion
Journal of Comparative Neurology, Volume 533, Issue 3, March 2025.Schematic summary of the presence and characteristics of putative telocytes in human dorsal root ganglia (DRG). In‐depth in silico analysis of sequencing data suggests the presence of nine distinct telocyte subtypes in human DRG and defined more than 3000 predicted receptor–ligand interactions between neurons and telocytes.
Rainer V. Haberberger +4 more
wiley +1 more source
A Novel ACKR2-Dependent Role of Fibroblast-Derived CXCL14 in Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer [PDF]
Clinical Cancer Research, 2019 Abstract Purpose: Fibroblasts expressing the orphan chemokine CXCL14 have been previously shown to associate with poor breast cancer prognosis and promote cancer growth. This study explores the mechanism underlying the poor survival associations of stromal CXCL14.
Elin Sjöberg +12 more
openaire +2 more sources
Beeinflussung der diabetischen Nephropathie durch den atypischen Chemokinrezeptor 2 [PDF]
, 2023 Die diabetische Nephropathie gehört zu den bedeutendsten Pathologien der Nephrologie mit hoher klinischer Relevanz. Inflammatorische Prozesse mit leukozytärer Infiltration in das renale Gewebe spielen eine wichtige pathophysiologische Rolle, tragen zur ...
Mertsch, Manuela
core
Cancer Communications, Volume 45, Issue 12, Page 1760-1766, December 2025.
Carine Ngo +30 more
wiley +1 more source
Tertiary Lymphoid Structure in Dental Pulp: The Role in Combating Bacterial Infections
Advanced Science, Volume 12, Issue 1, January 9, 2025.TLS is involved in the immune responses to cancer and other chronic inflammatory conditions, often associated with favorable clinical outcomes. In this context, dental pulp serves as an ideal model for chronic infection, and is used here to elucidate the specific contributions of TLS to the immune response and to identify the drivers of its formation ...
Ruiqi Li +12 more
wiley +1 more source
Effect of neutrophils on tumor immunity and immunotherapy resistance with underlying mechanisms
Cancer Communications, Volume 45, Issue 1, Page 15-42, January 2025.Abstract Neutrophils are key mediators of the immune response and play essential roles in the development of tumors and immune evasion. Emerging studies indicate that neutrophils also play a critical role in the immunotherapy resistance in cancer. In this review, firstly, we summarize the novel classification and phenotypes of neutrophils and describe ...
Jiali Yao +3 more
wiley +1 more source
Role of placental inflammatory mediators and growth factors in patients with rheumatic diseases with a focus on systemic sclerosis [PDF]
, 2020 Objectives: Pregnancy in SSc is burdened with an increased risk of obstetric complications. Little is known about the underlying placental alterations.
Beneventi, Fausta +10 more
core +1 more source
American Journal of Reproductive Immunology, Volume 93, Issue 1, January 2025.ABSTRACT Problem Although it is still uncertain whether Severe Acute Respiratory Coronavirus (SARS‐CoV‐2) placental infection and vertical transmission occur, inflammation during early pregnancy can have devastating consequences for gestation itself and the growing fetus.
Humblenoble Stembridge Ayuk +5 more
wiley +1 more source
Cancer Science, Volume 116, Issue 1, Page 44-55, January 2025.We found that DILI promotes liver metastasis of colorectal cancer in a classic DILI mouse model. Further analysis using high‐throughput transcriptome sequencing and proteomics identified ORM2 as a key gene that promotes liver metastasis. ORM2 upregulation enhances tumor cell migration by promoting EMT of tumor cells and increasing the expression of ...
Xundong Wei +5 more
wiley +1 more source