Results 21 to 30 of about 994 (172)

Immunohistochemical Expression of Haptoglobin in Skin Lesions of Hidradenitis Suppurativa

Life
Background: Meta-inflammation is a hallmark of hidradenitis suppurativa (HS). Research on meta-inflammation in HS is growing, but there is still no research on haptoglobin as an inflammatory protein in lesional HS skin.
Nessr Abu Rached, Hanna Telkemeyer, Marina Skrygan, Martin Doerler, Yannik Haven, Lennart Ocker, Daniel Myszkowski, Thomas Meyer, Markus Stücker, Eggert Stockfleth, Falk G. Bechara   +10 more
doaj   +1 more source

Hidradenitis Suppurativa: Higher Tobacco Pack-Years in Patients with Metabolic Comorbidities

Life
Background: Hidradenitis suppurativa (HS) is a chronic, relapsing inflammatory dermatosis with substantial quality-of-life impact. HS frequently co-exists with obesity and metabolic comorbidities. Cigarette smoking is highly prevalent and has been linked
Yannik Haven, Nessr Abu Rached, Charlotte Michel, Daniel Myszkowski, Lennart Ocker, Ioannis A. Zeglis, Eggert Stockfleth, Falk G. Bechara   +7 more
doaj   +1 more source

The Impact of Surgery on Quality of Life in Hidradenitis Suppurativa: Results from a Prospective Single-Center Study

Life
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs quality of life. Treatment typically involves a patient-oriented combination of medical therapies, surgery, and lifestyle modifications.
Lennart Ocker, Nessr Abu Rached, Anna Koller, Carolin Frost, Riina Käpynen, Falk G. Bechara   +5 more
doaj   +1 more source

Reproductive Potential and Outcomes in Patients with Hidradenitis Suppurativa: Clinical Profile and Therapeutic Implications

Life, 2021
There are scarce data available regarding the impact of hidradenitis suppurativa (HS) on fertility, course and outcome of pregnancy and risk associated with treatments.
Trinidad Montero-Vilchez, Luis Salvador-Rodriguez, Andrea Rodriguez-Tejero, Manuel Sanchez-Diaz, Salvador Arias-Santiago, Alejandro Molina-Leyva   +5 more
doaj   +1 more source

A state-of-the-art systematic review of cancer in hidradenitis suppurativa

Annals of Medicine
Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory disease associated with an increased risk of malignancy. The aim of this systematic review was to investigate the prevalence of different malignancies in HS.Methods This review meets the ...
Nessr Abu Rached, Jonas Rüth, Thilo Gambichler, Lennart Ocker, Falk G. Bechara   +4 more
doaj   +1 more source

Epidemiology of hidradenitis suppurativa in Poland in relation to international data

Przegląd Dermatologiczny, 2017
Hidradenitis suppurativa (acne inversa) is a chronic, inflammatory, recurrent, debilitating disease of hair follicles manifested by painful, deepseated, inflamed lesions localized in intertriginous areas.
Łukasz Matusiak, Andrzej Kaszuba, Dorota Krasowska, Waldemar Placek, Jacek Szepietowski   +4 more
doaj   +1 more source

Immunohistochemical Characterisation of the Interstitial Inflammatory Environment: T-Cell- and B-Cell-Dominant Subtypes of Hidradenitis Suppurativa

Dermatopathology
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a complex immune response. Given the considerable heterogeneity of the clinical phenotype of HS, this study aimed to analyse the immunohistochemical pattern of interstitial ...
Nessr Abu Rached, Stefanie Bruckmüller, Martin Doerler, Hanna Telkemeyer, Lennart Ocker, Yannik Haven, Daniel Myszkowski, Markus Stücker, Eggert Stockfleth, Falk G. Bechara   +9 more
doaj   +1 more source

Efficacy of Biologics for Hidradenitis Suppurativa: A Network Meta Analysis and Meta Regression for Baseline Disease Severity

Australasian Journal of Dermatology, EarlyView.
ABSTRACT Hidradenitis Suppurativa is a challenging, heterogeneous inflammatory skin disease, with three approved biologic therapies. No head‐to‐head studies exist comparing these therapeutic modalities, and previous work has identified the influence of baseline disease severity upon clinical response.
James Pham, Tara Sholji, Marra Aghajani, Ericka Maye, Kate Burrell, Cindy Kok, John W. Frew   +6 more
wiley   +1 more source

Economic burden of hidradenitis suppurativa based on healthcare resource utilization: German claims data analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease affecting approximately 0.1% of the German population. Patients with HS require substantial healthcare resource utilization. This study aimed to assess the economic burden associated with HS in Germany.
Falk G. Bechara, Tanja Tran, Sandeep Kiri, Romy Bley, Kathrin Schlüter, Claudia Grellmann, Sima Melnik, Sylke Schneider‐Burrus   +7 more
wiley   +1 more source

Towards the development of upgrade criteria for the treatment of hidradenitis suppurativa with biologics

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Forty‐three HS specialists from 22 European countries reported adherence to HS guidelines and use of antibiotics before biologics despite limited efficacy and rapid relapse (49% within 1–3 months). Seventy‐nine per cent supported short‐term biologics for severe Hurley I disease.
Georgios Nikolakis, Erkan Alpsoy, Monika Arenbergerova, Falk G. Bechara, Farida Benhadou, Joana Cabete, Raffaele Dante Caposiena Caro, Giovanni Damiani, Maia Delage Toriel, Veronique Del Marmol, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Evgeniya Hristakieva, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Niamh Kearney, Brian Kirby, Natalia Kirsten, Piotr K. Krajewski, Vesta Kucinskiene, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Francesca Prignano, Tadas Raudonis, Hans Christian Ring, Marco Romanelli, Samed Şahin, Ditte M. L. Saunte, Linnea Thorlacius, Thrasyvoulos Tzellos, Hessel H. Van Der Zee, Kelsey Van Straalen, Christos C. Zouboulis   +41 more
wiley   +1 more source