Results 51 to 60 of about 2,497 (169)

Development of an ic-ELISA and an immunochromatographic strip assay for the detection of aconitine

open access: yesFood and Agricultural Immunology, 2020
The medicinal properties and toxicity of aconitine in traditional Chinese medicine have caused widespread concern. In this study, we screened a highly specific and sensitive monoclonal antibody with an IC50 of 3.65 ng/mL generated by immunizing mice and ...
Shaozhen Li   +3 more
doaj   +1 more source

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

open access: yesFrontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia   +26 more
doaj   +1 more source

A retrospective study on laboratory‐confirmed acute Chinese medicine poisoning involving aconite in Hong Kong from 2008 to 2020

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Territory‐wide epidemiological studies of acute Chinese medicine poisoning involving aconite after 2010 are lacking. Objectives To characterise the latest trends, presumed causes, clinical presentations, healthcare utilisation and patient outcomes of such poisoning cases in Hong Kong.
Rex Pui Kin Lam   +9 more
wiley   +1 more source

Ester hydrolysis differentially reduces aconitine-induced anti-hypersensitivity and acute neurotoxicity: Involvement of spinal microglial dynorphin expression and implications for Aconitum processing

open access: yesFrontiers in Pharmacology, 2016
Aconitines, including bulleyaconitine A, probably the most bioactive and abundant alkaloids in Aconitum plant, are a group of diester C19-diterpenoid alkaloids with one acetylester group attached to C8 of the diterpenoid skeleton and one benzoylester ...
Teng-Fei Li, Yong-Xiang Wang, Nian Gong
doaj   +1 more source

Krystallisirtes Aconitin [PDF]

open access: yesArchiv der Pharmazie, 1871
n ...
openaire   +2 more sources

Aconitine Induced Pulmonary Edema.

open access: yesExperimental Biology and Medicine, 1962
SummaryAcute pulmonary edema is induced by bilateral injections of dilute solutions of aconitine into the preoptic area of the hypothalamus of rats. The severity of the edema is greatly reduced but not abolished by lesions of the posterior hypothalamus. Deep barbiturate anesthesia greatly reduces aconitine edema.
L D, SEAGER, C D, WOOD
openaire   +2 more sources

Traditional Chinese Medicine Modernization in Diagnosis and Treatment: Utilizing Artificial Intelligence and Nanotechnology

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu   +7 more
wiley   +1 more source

Understanding Atrial Fibrillation Complexity Through the Lens of Turbulence Dynamics: Implications for Treatment Strategies

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 2, Page 400-412, February 2026.
ABSTRACT Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. Its incidence increases significantly with age and has become a major global public health issue. Although research into the mechanisms of AF has spanned over a century‐ranging from the reentry theory to the rotor hypothesis‐none of these
Xin Chu   +4 more
wiley   +1 more source

Identification of Hub Genes in Protective Effect of Astragaloside IV on Aconitine-Induced Cardiac Damage in Zebrafish Based on Bioinformatics Analysis

open access: yesFrontiers in Pharmacology, 2020
Accumulating evidence suggests that Astragaloside IV (AS-IV) improves cardiac function and protects the cardiovascular system. However, the molecular targets involved remain ambiguous. In this work, we report research suggesting that AS-IV can antagonize
Mingzhu Wang   +6 more
doaj   +1 more source

Integrating Traditional Wisdom With Modern Science: Ginsenosides as Antiheart Failure Agents

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Heart failure (HF), as the terminal stage of various cardiovascular diseases, remains a global health challenge with persistently high morbidity and mortality rates. Although current therapies—including angiotensin receptor–neprilysin inhibitors, sodium‐glucose cotransporter‐2 inhibitors, and cardiac resynchronization therapy—have improved outcomes ...
Li Zhou   +6 more
wiley   +1 more source

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