Results 31 to 40 of about 2,497 (169)

Insecticidal effect of aconitine on the rice brown planthoppers.

open access: yesPLoS ONE, 2019
The brown planthopper, Nilaparvata lugens (Stål), severely damages rice production and develops high level resistance to several classes of insecticides. To find potential insecticidal resources is always important.
Shuqin Wei   +4 more
doaj   +1 more source

An Effective Phytoconstituent Aconitine: A Realistic Approach for the Treatment of Trigeminal Neuralgia

open access: yesMediators of Inflammation, 2021
Trigeminal neuralgia pain remains a challenge to treat. Natural compounds may be promising options for relieving pain. This study was aimed at investigating the effects of aconitine in a rat model of trigeminal neuralgia pain.
Dilek Çankal   +4 more
doaj   +1 more source

Compatibility of Fuzi and Ginseng Significantly Increase the Exposure of Aconitines

open access: yesFrontiers in Pharmacology, 2022
The herb-pair ginseng-Fuzi (the root of Aconitum carmichaelii) is the material basis of Shenfu prescriptions and is popular in traditional Chinese medicine for the treatment of heart failure, and even shock with severe-stage of COVID-19.
Ze-Yan Chen   +14 more
doaj   +1 more source

Arctigenin, a Potential Anti-Arrhythmic Agent, Inhibits Aconitine-Induced Arrhythmia by Regulating Multi-Ion Channels

open access: yesCellular Physiology and Biochemistry, 2013
Background/Aims: Arctigenin possesses biological activities, but its underlying mechanisms at the cellular and ion channel levels are not completely understood.
Zhenying Zhao   +6 more
doaj   +1 more source

Adsorption and Inhibition Analysis of Aconitine and Tubocurarine Alkaloids as Eco-friendly Inhibitors of Pitting Corrosion in ASTM – A47 Low Carbon Steel in HCl Acid Environment

open access: yesIndonesian Journal of Chemistry, 2022
Corrosion is an enormous challenge in all sectors of the economy, especially to those working with metals. The research on the adsorption and inhibition analysis of aconitine alkaloid (ACA) and tubocurarine alkaloid (TBA) as eco-friendly inhibitors of ...
Benedict Ushaka Ugi   +7 more
doaj   +1 more source

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano   +5 more
wiley   +2 more sources

Aconitine: A potential novel treatment for systemic lupus erythematosus

open access: yesJournal of Pharmacological Sciences, 2017
Background: Aconitum plants have been widely used in China for thousands of years. Recent evidences indicate that aconitine, the main active ingredient of Aconitum, has immunomodulatory properties that might be useful for treating autoimmune diseases ...
Xiaodong Li   +4 more
doaj   +1 more source

Recurrent malignant ventricular arrhythmias and paresthesia—a mystery revealed as aconitine poisoning: a case report

open access: yesJournal of Medical Case Reports, 2023
Background We report a case of a clinical challenge lasting for 12 months, with severe and unresolved clinical features involving several medical disciplines.
Ole Christian Mjølstad   +8 more
doaj   +1 more source

A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity

open access: yesDrug Design, Development and Therapy, 2021
Jinxia Wei,* Simiao Fan,* Hongxin Yu,* Lexin Shu, Yubo Li School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China*These authors contributed equally to this ...
Wei J, Fan S, Yu H, Shu L, Li Y
doaj  

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