Results 31 to 40 of about 264 (129)
Journal of Medical Case Reports, 2023 Background We report a case of a clinical challenge lasting for 12 months, with severe and unresolved clinical features involving several medical disciplines.
Ole Christian Mjølstad +8 more
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Construction of a Stable Expression Cell Line of Human Phospholamban
Fayixue Zazhi, 2021 ObjectiveTo construct a cell line that can stably express human phospholamban（PLN） and initially explore its application in the study of myocardial toxicity mechanism.MethodsFastCloning method was used to insert the open reading frame sequence of target ...
CHEN Lan-qing +7 more
doaj +1 more source
Hematological and Histopathological Effects of Subacute Aconitine Poisoning in Mouse
Frontiers in Veterinary Science, 2022 Aconitine is the principal toxic ingredient of Aconitum, which can cause systemic poisoning involving multiple organs and systems after animal ingestion.
Hao Lu +7 more
doaj +1 more source
The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
MedComm, Volume 7, Issue 6, June 2026.Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Analytical Aspects of Diterpene Alkaloid Poisoning with Monkshood
Natural Product Communications, 2009 A sensitive and specific method for aconitine extraction from biological samples was developed. Aconitine, the main toxic alkaloid from plants belonging to Aconitum species (family Ranunculaceae), was determined in plant material by an external standard ...
Maria Laura Colombo +5 more
doaj +1 more source
Cancer Science, Volume 117, Issue 6, Page 1651-1666, June 2026.Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee +4 more
wiley +1 more source
Advanced Science, Volume 13, Issue 22, 17 April 2026.A cold‐lamination strategy is introduced to fabricate ultrathin, nanomesh‐reinforced hydrogel bioelectronics with controlled thickness, tunable mechanics, and reversible adhesion. By mechanically interlocking a TPU nanomesh within a temperature‐responsive hydrogel, the platform enables robust epidermal and implantable cardiac interfaces, supporting ...
Hui Chen +10 more
wiley +1 more source
The Turkish Journal of GastroenterologyBackground/Aims: The incidence of colorectal cancer (CRC) has been increasing in recent years worldwide. Aconitine is a diester diterpenoid alkaloid that exhibits an antitumor role in several cancers.
Xuehui Li +4 more
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Gut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley +1 more source
Effect of processing on the alkaloids in Aconitum tubers by HPLC-TOF/MS
Journal of Pharmaceutical Analysis, 2017 According to the Chinese Pharmacopoeia 2015, only processed Aconitum tubers can be clinically applied, and the effect of processing is unclear. This research aimed to explore the effect of processing on cardiac efficacy of alkaloids in Aconitum tubers ...
Min Liu +6 more
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