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Sweroside Alleviated Aconitine-Induced Cardiac Toxicity in H9c2 Cardiomyoblast Cell Line
Frontiers in Pharmacology, 2018 Aconitine is the main bioactive ingredient of Aconitum plants, which are well-known botanical herbs in China. Aconitine is also notorious for its high cardiotoxicity, as it can induce life-threatening ventricular arrhythmias. Unfortunately, there are few
Li-Qun Ma +8 more
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Journal of Pharmacological Sciences, 2014 .: The acetylcholine receptor–operated K+ (KACh) channel may be a novel target for atrial-specific antiarrhythmic therapy. Recently it has been demonstrated that tertiapin, a selective blocker of KACh channel, suppressed aconitine-induced atrial ...
Kazumasa Suzuki +5 more
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Network-analysis-guided synthesis of weisaconitine D and liljestrandinine. [PDF]
, 2015 General strategies for the chemical synthesis of organic compounds, especially of architecturally complex natural products, are not easily identified. Here we present a method to establish a strategy for such syntheses, which uses network analysis.
Gallego, GM +8 more
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Research Progress on the Molecular Mechanisms of Toxicology of Ethanol-Aconitine Induced Arrhythmia [PDF]
Fayixue Zazhi, 2020 Aconitum is one of the most widely used Chinese herbal medicines, and aconitine is the major toxic component in it. Aconitine can induce a variety of arrhythmias, resulting in death. Acute ethanol consumption causes arrhythmia as well.
PAN Mei-chen, ZHOU Xiao-wei, LIU Yan,et al.
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Herbal Combination of <i>Angelica gigas</i>, <i>Zingiber officinale</i>, and <i>Aconitum carmichaeli</i> Alleviates High Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice Through NRF2-Mediated Regulation of Adipogenesis and Non-Shivering Thermogenesis. [PDF]
Food Sci NutrThe multi‐herbal formula JI017, consisting of Angelica gigas, Zingiber officinale , and Aconitum carmichaeli, alleviates high‐fat diet‐induced non‐alcoholic fatty liver disease by activating the NRF2 antioxidant pathway. This central mechanism suppresses adipogenesis in the liver and white adipose tissues while simultaneously enhancing thermogenesis in
Kim H +16 more
europepmc +2 more sources
XXV.—The oxidation of aconitine [PDF]
J. Chem. Soc., Trans., 1915 n ...
Barger, George, Field, Ellen
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Molecules, 2022 Aconiti Lateralis Radix Praeparata (Fu Zi) is the processed lateral root of Aconitum carmichaelii Debx, which is widely used in emergency clinics. Poisoning incidents and adverse reactions occur with the improper intake of Fu Zi.
Liang Yang +9 more
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Arrhythmogenic Risk Assessment Following Four-Week Pretreatment With Nicotine and Black Tea in Rat [PDF]
, 2015 Background: There is the controversy concerning the main component of tobacco, which is responsible for its arrhythmogenesis. In addition, there is the lack of adequate information about the influence of combination of black tea and nicotine on heart ...
Ghasemipoor Afshar, Elham +4 more
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