Results 21 to 30 of about 2,497 (169)

Sweroside Alleviated Aconitine-Induced Cardiac Toxicity in H9c2 Cardiomyoblast Cell Line

open access: yesFrontiers in Pharmacology, 2018
Aconitine is the main bioactive ingredient of Aconitum plants, which are well-known botanical herbs in China. Aconitine is also notorious for its high cardiotoxicity, as it can induce life-threatening ventricular arrhythmias. Unfortunately, there are few
Li-Qun Ma   +8 more
doaj   +1 more source

Termination of Aconitine-Induced Atrial Fibrillation by the KACh-Channel Blocker Tertiapin: Underlying Electrophysiological Mechanism

open access: yesJournal of Pharmacological Sciences, 2014
.: The acetylcholine receptor–operated K+ (KACh) channel may be a novel target for atrial-specific antiarrhythmic therapy. Recently it has been demonstrated that tertiapin, a selective blocker of KACh channel, suppressed aconitine-induced atrial ...
Kazumasa Suzuki   +5 more
doaj   +1 more source

XXV.—The oxidation of aconitine [PDF]

open access: yesJ. Chem. Soc., Trans., 1915
n ...
Barger, George, Field, Ellen
openaire   +1 more source

Research Progress on the Molecular Mechanisms of Toxicology of Ethanol-Aconitine Induced Arrhythmia [PDF]

open access: yesFayixue Zazhi, 2020
Aconitum is one of the most widely used Chinese herbal medicines, and aconitine is the major toxic component in it. Aconitine can induce a variety of arrhythmias, resulting in death. Acute ethanol consumption causes arrhythmia as well.
PAN Mei-chen, ZHOU Xiao-wei, LIU Yan,et al.
doaj   +1 more source

Metabolic Behaviors of Aconitum Alkaloids in Different Concentrations of Aconiti Lateralis Radix Praeparata and Effects of Aconitine in Healthy Human and Long QT Syndrome Cardiomyocytes

open access: yesMolecules, 2022
Aconiti Lateralis Radix Praeparata (Fu Zi) is the processed lateral root of Aconitum carmichaelii Debx, which is widely used in emergency clinics. Poisoning incidents and adverse reactions occur with the improper intake of Fu Zi.
Liang Yang   +9 more
doaj   +1 more source

Observation on facilitation and attenuation effect of electroacupuncture combined with aconitine for treatment of heart failure in rats

open access: yes针刺研究, 2021
Objective To observe the influence of electroacupuncture(EA) combined with aconitine on the hemodyna-mics, echocardiogram, and arrhythmias in heart failure rats, so as to explore the facilitation and attenuation effects of EA combined with aconitine ...
LIU Qun   +7 more
doaj  

Aconitine in Neuralgia [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1885
n ...
openaire   +2 more sources

Pseud‐Aconitin [PDF]

open access: yesArchiv der Pharmazie, 1871
n ...
openaire   +1 more source

Improved Biosafety and Transdermal Delivery of Aconitine via Diethylene Glycol Monoethyl Ether-Mediated Microemulsion Assisted with Microneedles

open access: yesPharmaceutics, 2020
In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang   +6 more
doaj   +1 more source

A Comprehensive In Silico Method to Study the QSTR of the Aconitine Alkaloids for Designing Novel Drugs

open access: yesMolecules, 2018
A combined in silico method was developed to predict potential protein targets that are involved in cardiotoxicity induced by aconitine alkaloids and to study the quantitative structure–toxicity relationship (QSTR) of these compounds.
Ming-Yang Wang   +5 more
doaj   +1 more source

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