Results 41 to 50 of about 4,322 (208)

Aconitine: A potential novel treatment for systemic lupus erythematosus

open access: yesJournal of Pharmacological Sciences, 2017
Background: Aconitum plants have been widely used in China for thousands of years. Recent evidences indicate that aconitine, the main active ingredient of Aconitum, has immunomodulatory properties that might be useful for treating autoimmune diseases ...
Xiaodong Li   +4 more
doaj   +1 more source

Recurrent malignant ventricular arrhythmias and paresthesia—a mystery revealed as aconitine poisoning: a case report

open access: yesJournal of Medical Case Reports, 2023
Background We report a case of a clinical challenge lasting for 12 months, with severe and unresolved clinical features involving several medical disciplines.
Ole Christian Mjølstad   +8 more
doaj   +1 more source

A New Strategy for the Rapid Identification and Validation of the Direct Targets of Aconitine-Induced Cardiotoxicity

open access: yesDrug Design, Development and Therapy, 2021
Jinxia Wei,* Simiao Fan,* Hongxin Yu,* Lexin Shu, Yubo Li School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of China*These authors contributed equally to this ...
Wei J, Fan S, Yu H, Shu L, Li Y
doaj  

Construction of a Stable Expression Cell Line of Human Phospholamban

open access: yesFayixue Zazhi, 2021
ObjectiveTo construct a cell line that can stably express human phospholamban(PLN) and initially explore its application in the study of myocardial toxicity mechanism.MethodsFastCloning method was used to insert the open reading frame sequence of target ...
CHEN Lan-qing   +7 more
doaj   +1 more source

Poison, plants and Palaeolithic hunters. An analytical method to investigate the presence of plant poison on archaeological artefacts [PDF]

open access: yes, 2015
In this paper we present the development of a method for the detection of toxic substances on ancient arrow points. The aim is to go back in time until the Palaeolithic period in order to determine if poisonous substances were used to enhance the hunting
Christian C. Yde (1583899)   +5 more
core   +3 more sources

Hematological and Histopathological Effects of Subacute Aconitine Poisoning in Mouse

open access: yesFrontiers in Veterinary Science, 2022
Aconitine is the principal toxic ingredient of Aconitum, which can cause systemic poisoning involving multiple organs and systems after animal ingestion.
Hao Lu   +7 more
doaj   +1 more source

Pyrethroids and Nectar Toxins Have Subtle Effects on the Motor Function, Grooming and Wing Fanning Behaviour of Honeybees (Apis mellifera) [PDF]

open access: yes, 2015
Sodium channels, found ubiquitously in animal muscle cells and neurons, are one of the main target sites of many naturally-occurring, insecticidal plant compounds and agricultural pesticides.
A Choudhary   +47 more
core   +4 more sources

Analytical Aspects of Diterpene Alkaloid Poisoning with Monkshood

open access: yesNatural Product Communications, 2009
A sensitive and specific method for aconitine extraction from biological samples was developed. Aconitine, the main toxic alkaloid from plants belonging to Aconitum species (family Ranunculaceae), was determined in plant material by an external standard ...
Maria Laura Colombo   +5 more
doaj   +1 more source

On mechanism of antiarrhythmic action of some dimethylphenylacetamide derivatives [PDF]

open access: yes, 2018
The study aim was to identify essential elements of the antiarrhythmic action mechanism of tertiary and quaternary derivatives of Dimethylphenylacetamide.
Blinova, E. V.   +4 more
core   +2 more sources

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