Results 41 to 50 of about 264 (129)

Acute poisoning of aconitum: A case report and resuscitative emergency management with amiodarone

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2022
Aconitine, a plant alkaloid is a usual constituent of various over-the-counter herbal remedies and is an uncommon cause of deliberate poisoning. Herein, we describe an unusual case of poisoning in a young male due to accidental ingestion of aconitine ...
Gautam Jesrani, Amanjot Kaur, Monica Gupta, Harsheel Gupta   +3 more
doaj   +1 more source

Traditional Chinese Medicine as an Integrative Adjunct in Oncology Perioperative Practice: Analgesia, Immune Modulation, and Translational Challenges

Medicine Bulletin, Volume 2, Issue 2, Page 184-204, March 2026.
ABSTRACT Traditional Chinese medicine (TCM), including herbal analgesic adjuvants and acupuncture‐based interventions, has gained increasing attention as an integrative strategy for perioperative pain management in oncology. Bioactive phytochemicals—such as terpenoids, flavonoids, alkaloids, and polyphenols—exert multimodal pharmacological effects ...
Yuqin Tang, Zheng Luo, Xu Zhao, Yongqiang Zhang, Mingyang Sun, Jiaqiang Zhang   +5 more
wiley   +1 more source

Aconitine promotes ROS-activated P38/MAPK/Nrf2 pathway to inhibit autophagy and promote myocardial injury

Journal of Cardiothoracic Surgery
Background Aconitine has cardiotoxicity, but the mechanism of cardiotoxicity induced by aconitine is limited. The aim of this study was to investigate the mechanism of myocardial injury induced by aconitine.
Chunai Yang, Jinxiao Fu, Fenshuang Zheng, Yangshan Fu, Xueqiong Duan, Ruiling Zuo, Junbo Zhu   +6 more
doaj   +1 more source

Development of an ic-ELISA and an immunochromatographic strip assay for the detection of aconitine

Food and Agricultural Immunology, 2020
The medicinal properties and toxicity of aconitine in traditional Chinese medicine have caused widespread concern. In this study, we screened a highly specific and sensitive monoclonal antibody with an IC50 of 3.65 ng/mL generated by immunizing mice and ...
Shaozhen Li, Xiaoling Wu, Hua Kuang, Liqiang Liu   +3 more
doaj   +1 more source

Antiarrhythmic properties of N-Deacetyllappaconitine Hydrochloride

Фармакокинетика и Фармакодинамика, 2022
The aim of the investigation was the research of the N-deacetyllappaconitine hydrochloride antiarrhythmic properties. It was found that the studied substance was effective on the cardiac arrhythmias model caused by aconitine hydrochloride, but does not ...
S. A. Kryzhanovskii, M. S. Yunusov, I. B. Tsorin, V. V. Barchukov, E. I. Barchukova   +4 more
doaj   +1 more source

Krystallisirtes Aconitin [PDF]

Archiv der Pharmazie, 1871
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openaire   +2 more sources

Aconitine Induced Pulmonary Edema.

Experimental Biology and Medicine, 1962
SummaryAcute pulmonary edema is induced by bilateral injections of dilute solutions of aconitine into the preoptic area of the hypothalamus of rats. The severity of the edema is greatly reduced but not abolished by lesions of the posterior hypothalamus. Deep barbiturate anesthesia greatly reduces aconitine edema.
L D, SEAGER, C D, WOOD
openaire   +2 more sources

A retrospective study on laboratory‐confirmed acute Chinese medicine poisoning involving aconite in Hong Kong from 2008 to 2020

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 1, February 2026.
Abstract Background Territory‐wide epidemiological studies of acute Chinese medicine poisoning involving aconite after 2010 are lacking. Objectives To characterise the latest trends, presumed causes, clinical presentations, healthcare utilisation and patient outcomes of such poisoning cases in Hong Kong.
Rex Pui Kin Lam, Shuk Ching Ting, Tsz Kit Chow, Ka Kit Chua, Ping Yui Ku, Chi Keung Chan, Man Li Tse, Eric Ho Yin Lau, Jin Zhao, Timothy Hudson Rainer   +9 more
wiley   +1 more source

Ester hydrolysis differentially reduces aconitine-induced anti-hypersensitivity and acute neurotoxicity: Involvement of spinal microglial dynorphin expression and implications for Aconitum processing

Frontiers in Pharmacology, 2016
Aconitines, including bulleyaconitine A, probably the most bioactive and abundant alkaloids in Aconitum plant, are a group of diester C19-diterpenoid alkaloids with one acetylester group attached to C8 of the diterpenoid skeleton and one benzoylester ...
Teng-Fei Li, Yong-Xiang Wang, Nian Gong
doaj   +1 more source

Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos

Frontiers in Pharmacology, 2021
Aconitine (AC), one of the bioactive diterpenoid alkaloids extracted from Aconitum plants, is widely used in traditional herbal medicine to treat various diseases.
Qing Xia, Qing Xia, Qing Xia, Shuo Gao, Shuo Gao, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Samuel Rajendran Rapael Gnanamuthu, Kaiyan Zhuang, Kaiyan Zhuang, Kaiyan Zhuang, Zhenzhen Song, Zhenzhen Song, Zhenzhen Song, Yun Zhang, Yun Zhang, Yun Zhang, Xue Wang, Xue Wang, Xue Wang, Pengfei Tu, Pengfei Tu, Pengfei Tu, Jianheng Li, Kechun Liu, Kechun Liu, Kechun Liu   +26 more
doaj   +1 more source