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Aconitum carmichaelii Debeaux, cultivated as a medicinal plant in western China

Genetic Resources and Crop Evolution, 2016
Large-scale cultivation of Aconitum carmichaelii Debeaux has been carried out on medicinal plant farms in western China for over 1000 years. After detoxification, the fleshy roots are officially used as aconite in herbal medicine.
Ma Yu, Jing Huang, Da-Bin Hou
exaly   +2 more sources

Ethnopharmacological use, pharmacology, toxicology, phytochemistry, and progress in Chinese crude drug processing of the lateral root of Aconitum carmichaelii Debeaux. (Fuzi): A review

Journal of Ethnopharmacology, 2023
The lateral root of Aconitum carmichaelii Debeaux. (also known as Fuzi in Chinese) is a toxic Chinese medicine but widely used in clinical practice with remarkable effects. It is specifically used to treat cardiovascular diseases, rheumatoid arthritis, and other diseases, in Korea, Japan, and India.This study aimed to summarize and discuss the effects ...
Wen-Jing Hu
exaly   +3 more sources

The highly toxic Aconitum carmichaelii Debeaux as a root vegetable in the Qinling Mountains (Shaanxi, China)

Genetic Resources and Crop Evolution, 2012
Aconitum spp. are highly toxic due to the presence of aconitine-type alkaloids. Aconitum carmichaelii Debeaux is one of the most important and most studied Chinese medicines. However the scientific literature contains only anecdotal references to the use of A. carmichaelii as a food plant. The aim of the study was to document the traditional alimentary
Łukasz Łuczaj
exaly   +2 more sources

A review on phytochemistry and pharmacological activities of the processed lateral root of Aconitum carmichaelii Debeaux

Journal of Ethnopharmacology, 2015
The processed lateral root of Aconitum carmichaelii Debeaux (Ranunculaceae), an extensively used traditional Chinese medicine, is known as Fuzi in China (Chinese: ), "bushi" in Japan, "Kyeong-Po Buja" in Korea, Chinese aconite, monkshood or Chinese wolfsbane. It has been used to treat shock resulting from acute myocardial infarction, low blood pressure,
Guohong Zhou, Liying Tang, Zhuju Wang
exaly   +3 more sources

Aqueous extract from Aconitum carmichaelii Debeaux reduces liver injury in rats via regulation of HMGB1/TLR4/NF-ΚB/caspase-3 and PCNA signaling pathways

Journal of Ethnopharmacology, 2016
Aconitum carmichaelii Debeaux is a well-known Chinese herb that has been used to treat liver diseases for many years in China. We investigated the effects of aqueous extract from Aconitum carmichaelii Debeaux (AEACD) on acute liver failure and identified the possible mechanisms of these effects.Specific pathogen-free (SPF) male Wistar rats were used to
Jian-Xing Luo
exaly   +3 more sources

Spectrum-effect relationships between UPLC fingerprints and bioactivities of crude secondary roots of Aconitum carmichaelii Debeaux (Fuzi) and its three processed products on mitochondrial growth coupled with canonical correlation analysis

Journal of Ethnopharmacology, 2014
The crude secondary roots of Aconitum carmichaelii Debeaux (Fuzi), together with its processed products, including Yanfuzi, Heishunpian and Paofupian, are commonly applied in clinic using for thousands of years, such as collapse, syncope, rheumatic fever, painful joints and various tumors.To explore the different effects of Fuzi and its processed ...
Yanling Zhao, Man Gong, Honghong Liu
exaly   +3 more sources

Analgesic C20-diterpenoid alkaloids from the lateral roots of Aconitum carmichaelii Debeaux: Natural inhibitors of NLRP3 activation

Bioorganic Chemistry
Five new C20-diterpenoid alkaloids carmaloidlines A-E (1-5) and a known C20-diterpenoid alkaloid (6) were isolated from the lateral roots of Aconitum carmichaelii Debeaux. Their structures were determined through spectrometric analysis and quantum chemical calculations. Meanwhile, the plausible biosynthetic pathways of 1-6 were also discussed.
Xue-Ge Pan, Cong-Yuan Xia
exaly   +3 more sources

New antidepressant diterpenoid alkaloids from Aconitum carmichaelii Debeaux: Potential inhibitors of NLRP3 activation

Bioorganic Chemistry
Targeting NOD-like receptor protein 3 (NLRP3) holds promise as a novel strategy for treating depression. Chemical investigation of the lateral roots of Aconitum carmichaelii Debeaux (Fuzi) led to the isolation of five new diterpenoid alkaloids acarmalines A-E (1-5).
Wei-Feng, Yin   +8 more
openaire   +2 more sources

Biocontrol Potential of Bacillus Velezensis Soil-4-2 Against Southern Blight of Aconitum Carmichaelii Debeaux

Pesticide Biochemistry and Physiology
Agroathelia rolfsii, causative agent of southern blight, is a soil-borne pathogen responsible for significant economic losses of Aconitum carmichaelii Debeaux. Biocontrol strategies based on beneficial microorganisms show broad prospects in sustainable plant disease management.
Yumei, Gou   +6 more
openaire   +2 more sources

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