Results 11 to 20 of about 427 (133)

Shenhuang Granules for patients with sepsis: study protocol of a multicenter, randomized, double-blind, placebo-controlled clinical trial [PDF]

Frontiers in Medicine
BackgroundSepsis is a life-threatening condition characterized by organ dysfunction due to a dysregulated host response to infection, with a persistently high mortality rate.
Meng-Yuan Shen, Ze-Jiong Li, Dan-Dan Feng, Dong-Dong Yang, Shan Liu, Yi-Heng Fu, Bang-Jiang Fang, Jian-Nong Wu   +7 more
doaj   +2 more sources

Effects of Active Components of Fuzi and Gancao Compatibility on Bax, Bcl-2, and Caspase-3 in Chronic Heart Failure Rats [PDF]

Evidence-Based Complementary and Alternative Medicine, Volume 2017, Issue 1, 2017., 2016
Hypaconitine (HA) and glycyrrhetinic acid (GA) are active components of Fuzi (Aconitum carmichaelii) and Gancao (Glycyrrhiza uralensis Fisch); they have been used in compatibility for chronic heart failure (CHF) from ancient times.
Haitong Wan, Huifen Zhou, Jiehong Yang, Li Yu, Liqin Wang, Yu He, Yuyan Zhang   +6 more
core   +6 more sources

Aconitum carmichaelii Debeaux: A systematic review on traditional use, and the chemical structures and pharmacological properties of polysaccharides and phenolic compounds in the roots

Journal of Ethnopharmacology, 2022
Aconitum carmichaelii, belonging to the Ranunculaceae family, is a widely used traditional herbal plant in Asian countries, especially in China. The lateral ("Fuzi") and mother ("Chuanwu") roots are the two main plant parts used in Traditional Chinese Medicine (TCM), where they are used in the treatment of acute myocardial infarction, heart failure ...
Yu-Ping Fu, Yuan-Feng Zou, Feiyi Lei
exaly   +3 more sources

Comparative clinical-related outcomes of Chinese patent medicines for cardiac hypertrophy: A systematic review and network meta-analysis of randomized clinical trials. [PDF]

Front Pharmacol, 2023
Background: Persistent pathological cardiac hypertrophy has been associated with increased risk of heart failure and even sudden death. Multiple Chinese patent medicines (CPMs) have gained attention as alternative and complementary remedies due to their ...
Zhang T, Xu H, Zhen D, Fu D, Zhao M, Wei C, Bai X.   +6 more
europepmc   +3 more sources

Pharmacokinetics, safety, and efficacy of Fuqi Guben Gao in the treatment of kidney-yang deficiency syndrome: a randomized, double-blind phase I trial [PDF]

Frontiers in Pharmacology
Introduction: Fuqi Guben Gao (FQGBG) is a botanical drug formulation composed of FuZi (FZ; Aconitum carmichaelii Debeaux [Ranunculaceae; Aconiti radix cocta]), Wolfberry (Lycium barbarum L. [Solanaceae; Lycii fructus]), and Cinnamon (Neolitsea cassia (L.)
Wei-Yi Cao, Wei-Yi Cao, Jun-Yu Liu, Jun-Yu Liu, Min Sun, Min Sun, Jing-Kun Wang, Jing-Kun Wang, Fang Lu, Fang Lu, Qiao-Ning Yang, Qiao-Ning Yang, Wan-Tong Zhang, Wan-Tong Zhang, Ming-Jie Zi, Ming-Jie Zi, Bai-E Zhang, Bai-E Zhang, Hong-Bin Liu, Hong-Bin Liu, Shu-Ge Wang, Shu-Ge Wang, Yi Wu, Yi Wu, Rong-Zu Wu, Wen-Di Wu, Rui Li, Rui Li, Zhao-Yun Zhu, Zhao-Yun Zhu, Rui Gao, Rui Gao   +31 more
doaj   +2 more sources

Detoxification and benefits on acute heart failure in mice- of fuziline using glycyrrhetinic acid: an integrated biochemical analysis [PDF]

Frontiers in Pharmacology
IntroductionAconiti Lateralis Radix Praeparata (lateral roots of Aconitum carmichaelii Debeaux, Fuzi), is commonly used to treat various cardiovascular diseases, particularly heart failure.
Nianwei Chang, Chunyu Hou, Yue Zhai, Wenying Zhang, Zengmei Hu, Xiaoying Wang   +5 more
doaj   +2 more sources

Inhalable songorine-integrated lipid nanomedicine for targeted ARDS therapy via repairing endothelial barrier and inactivating NLRP3 inflammasome [PDF]

Acta Pharmaceutica Sinica B
Acute respiratory distress syndrome (ARDS) is a life-threatening disease. In the clinical management of ARDS, current treatments such as glucocorticoids and protease inhibitors encounter significant challenges due to their high toxicity, limited ...
Haiyan Wang, Zhi-Chao Sun, Chunlei Dai, Ran Liao, Ran Lin, Liying Wang, Wenjun Fu, Ruhe Zhang, Danwen Zheng, Zhongde Zhang, Jun Wu, Yuntao Liu   +11 more
doaj   +2 more sources

Benzoylaconine Protects Skeletal Muscle Against Ischemia-Reperfusion Injury Through Activation of IF1-Dependent AMPK/Nrf2 Axis. [PDF]

Drug Des Devel Ther
Yidong Cui,1 Qingming Liu,2 Qiqiang Zhang,3 Xuemei Di,3 Hai Zhang3 1Department of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, 250014, People’s Republic of China;
Cui Y, Liu Q, Zhang Q, Di X, Zhang H.
europepmc   +3 more sources

Efficacy and safety of Chinese herbal medicine for multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Front Pharmacol
BackgroundMultiple sclerosis (MS) is an incurable, chronic, disabling disease that primarily affects young adults. Chinese herbal medicine (CHM) is increasingly recognized as a major form of complementary and alternative medicine; however, there is a ...
Guan X, Wu Y, Jia Q, Zheng Y, Zou M, Liu J, Sugimoto K, Gao Y.   +7 more
europepmc   +3 more sources

Shenfu injection improves isoproterenol-induced heart failure in rats by modulating co-metabolism and regulating the trimethylamine-N-oxide - inflammation axis. [PDF]

Front Pharmacol
Heart failure (HF) is a chronic condition that progressively worsens and continues to be a major financial burden and public health concern. The “gut-heart” axis provides an innovative perspective and therapeutic strategy for preventing and treating ...
Li L, Ye J, Zhao Z, Hu S, Liang H, Ouyang J, Hu Z.   +6 more
europepmc   +3 more sources