Results 51 to 60 of about 427 (133)

Integrating Traditional Wisdom With Modern Science: Ginsenosides as Antiheart Failure Agents

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Heart failure (HF), as the terminal stage of various cardiovascular diseases, remains a global health challenge with persistently high morbidity and mortality rates. Although current therapies—including angiotensin receptor–neprilysin inhibitors, sodium‐glucose cotransporter‐2 inhibitors, and cardiac resynchronization therapy—have improved outcomes ...
Li Zhou, Yanhua Li, Wenjie Yin, Xi Gu, Jiana Shi, Fan Yang, Satabdi Datta Choudhury   +6 more
wiley   +1 more source

Aconitine and its derivatives: bioactivities, structure-activity relationships and preliminary molecular mechanisms [PDF]

Aconitine (AC), which is the primary bioactive diterpene alkaloid derived from Aconitum L plants, have attracted considerable interest due to its unique structural feature.
Bo Tang, Chenjuan Zeng, Funeng Geng, Funeng Geng, Jie Kang, Lin Lu, Pengyu Zhao, Xin Zhang, Xiuying Ma, Ye Tian, Yuefei Geng   +10 more
core   +1 more source

Spectrum-effect relationships between high performance liquid chromatography fingerprints and bioactivities of charred areca nut [PDF]

, 2016
Purpose: To investigate the spectrum-effect relationships between high performance liquid chromatography (HPLC) fingerprints and duodenum contractility of charred areca nut (CAN) on rats.Methods: An HPLC method was used to establish the fingerprint of ...
Hu, Meibian, Liu, Yujie, Peng, Wei, Tao, Xingbao, Wu, Chunjie, Xie, Dashuai, Yan, Dan   +6 more
core   +2 more sources

Toxicology and detoxification processing of Fuzi (Aconitum carmichaelii Debeaux lateral root): a comprehensive review integrating historical perspectives and modern research

Frontiers in Pharmacology
Fuzi, the processed lateral root of Aconitum carmichaelii Debeaux (Ranunculaceae), is a vital yet highly toxic botanical drug in traditional Chinese medicine.
Yi Zhang, Huiwen Bai, Rongyi Zhou, Mumu Wei, Jiaqi Zhang, Xiaolu Yu, Jie Zhang   +6 more
doaj   +1 more source

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

Sini Decoction Improves Adrenal Function and the Short‐Term Outcome of Septic Rats through Downregulation of Adrenal Toll‐Like Receptor 4 Expression

Evidence-Based Complementary and Alternative Medicine, Volume 2018, Issue 1, 2018., 2018
Background. Sini Decoction (SND) is composed of Aconitum carmichaelii Debeaux, Zingiber officinale Roscoe, and Glycyrrhiza uralensis Fisch, having been used in China for centuries for collapsing phrase of disease. Studies reported that SND could alleviate inflammatory response, ameliorate microcirculatory disturbances, and improve shock reversal and ...
Fang Lai, Gengbiao Zhou, Shutao Mai, Xiaolian Qin, Wenting Liu, Yan Zhang, Dongping Xie, Yanna Weng, Jiongdong Du, Yi Zheng, Jiyang Liao, Yun Han, Jairo Kennup Bastos   +12 more
wiley   +1 more source

Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction

Addiction Biology, Volume 29, Issue 11, November 2024.
Experimental flowchart: NBDC is composed of various medicinal materials such as ginseng, astragalus and polygala. UPLC‐MS is used to analyse the components of NBDC. MA addiction rats is administered with NBDC. Blood samples are subjected to metabolomic analysis.
Bin Zhang, Chen Yang, Yuxiao Zheng, Xinliang Li, Xingguo Wang, Li Yuehui   +5 more
wiley   +1 more source

Garuda 5 (khyung lnga): Ecologies of Potency and the Poison-Medicine Spectrum of Sowa Rigpa’s Renowned ‘Black Aconite’ Formula [PDF]

, 2019
This article focuses on ethnographic work conducted at the Men-Tsee-Khang (Dharamsala, India) on Garuda 5 (khyung lnga), a commonly prescribed Tibetan medical formula.
van der Valk, Jan M. A.
core   +1 more source

Bioactive polysaccharides in different plant parts of Aconitum carmichaelii

Journal of the Science of Food and Agriculture, Volume 104, Issue 2, Page 746-758, 30 January 2024.
Abstract BACKGROUND Aconitum carmichaelii is an industrially cultivated medicinal plant in China and its lateral and mother roots are used in traditional Chinese medicine due to the presence of alkaloids. However, the rootlets and aerial parts are discarded after collection of the roots, and the non‐toxic polysaccharides in this plant have attracted ...
Yu‐Ping Fu, Cen‐Yu Li, Yuan‐Feng Zou, Xi Peng, Berit Smestad Paulsen, Helle Wangensteen, Kari Tvete Inngjerdingen   +6 more
wiley   +1 more source

Metabolomics of Clinical Poisoning by Aconitum Alkaloids Using Derivatization LC-MS [PDF]

, 2019
The root of Aconitum kusnezoffii (Caowu in Chinese, CW) is not only commonly used as a traditional Chinese medicine (TCM), but also served as a tonic in China. Due to its high toxicity, clinical poisoning cases induced by CW have frequently been reported.
Haiying Wu, Jian-Lin Wu, Jing Yang, Na Li, Xiqing Bian, Yida Zhang   +5 more
core   +1 more source