Results 71 to 80 of about 24,710 (219)

Synthesis of Poly(Itaconate)s With High Monomer Conversion Applying Emulsion Polymerization

Journal of Polymer Science, Volume 63, Issue 6, Page 1284-1296, 15 March 2025.
Itaconic acid and its derivatives are a promising and bio‐based substitute for oil‐based polymers such as acrylates. In this study, the optimization of polymerization of itaconic acid esters is described by applying emulsion polymerization leading to high reaction conversions and low residual monomer contents. ABSTRACT Itaconic acid and its derivatives
S. Charlotte Fischer von Mollard, Nico Ueberschaar, Martin Schreiber, Frank Kamphuis, Stefan Zechel, Martin D. Hager   +5 more
wiley   +1 more source

Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis.

PLoS ONE, 2021
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 1% of the world population. RA is associated with the presence of autoantibodies, of which anti-citrullinated protein antibodies (ACPA) are most prominent.
Linda M Slot, Rochelle D Vergroesen, Priscilla F Kerkman, Ellen Staudinger, Sanne Reijm, Hugo J van Dooren, Ellen I H van der Voort, Tom W J Huizinga, René E M Toes, Hans U Scherer   +9 more
doaj   +1 more source

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis [PDF]

, 2016
MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with ...
Alivernini, Stefano, Benvenuto, Roberta, Canestri, Silvia, Di Mario, Clara, Elmesmari, Aziza, Fedele, Anna Laura, Ferraccioli, Gianfranco, Gigante, Maria Rita, Gremese, Elisa, Kurowska-Stolarska, Mariola, Mangoni, Antonella, McInnes, Iain B., Petricca, Luca, Tolusso, Barbara   +13 more
core   +2 more sources

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Evaluation of the immune feature of ACPA-negative rheumatoid arthritis and the clinical value of matrix metalloproteinase-3

Frontiers in Immunology, 2022
Anti-citrullinated protein antibodies (ACPAs) are highly specific for the diagnosis of rheumatoid arthritis (RA). However, about one-third of RA patients are negative for ACPAs, which presents a challenge to the early diagnosis of RA. The purpose of this
Zhaojun Liang, Zhaojun Liang, Nan Wang, Nan Wang, Lili Shang, Lili Shang, Yanlin Wang, Yanlin Wang, Min Feng, Min Feng, Guangying Liu, Chong Gao, Jing Luo, Jing Luo   +13 more
doaj   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Anti-carbamylated protein antibodies as a new biomarker of erosive joint damage in systemic lupus erythematosus [PDF]

, 2018
Background: The application of more sensitive imaging techniques, such as ultrasonography (US), changed the concept of non-erosive arthritis in systemic lupus erythematosus (SLE), underlining the need for biomarkers to identify patients developing the ...
Alessandri, Cristiano, Ceccarelli, Fulvia, Cipriano, Enrica, Colasanti, Tania, Conti, Fabrizio, Mancini, Riccardo, Massaro, Laura, Natalucci, Francesco, Pendolino, Monica, Perricone, Carlo, Spinelli, Francesca Romana, Valesini, Guido   +11 more
core   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Prevalence of anti-citrullinated protein antibodies (ACPA) in patients with diffuse large B-cell lymphoma (DLBCL): a case-control study. [PDF]

PLoS ONE, 2014
BACKGROUND: Antibodies against citrullinated proteins (ACPA) have been recognised as the most specific serum marker for rheumatoid arthritis. However, serum autoantibodies such as anti-nuclear antibodies have also been detected in the sera of different ...
Gunter Assmann, Klara Shihadeh, Viola Poeschel, Niels Murawski, Jutta Conigliarou, Mei Fang Ong, Michael Pfreundschuh   +6 more
doaj   +1 more source

Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case–control study [PDF]

, 2013
Introduction: The aim of this study was to characterize anti-citrullinated peptide antibody (ACPA) serostatus in pre-clinical rheumatoid arthritis (RA) with and without Human Leukocyte Antigen-Shared Epitope (HLA-SE) alleles.
Arkema, Elizabeth V, Costenbader, Karen H, Goldstein, Barbara L, Grodstein, Francine, Karlson, Elizabeth W, Malspeis, Susan, Robinson, William, Rosner, Bernard, Sokolove, Jeremy, Wagner, Catriona A   +9 more
core   +2 more sources