Results 161 to 170 of about 5,357,823 (357)
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
XL. Report, read before the conference of mines, on the specific gravity of the coals of several mines of France; and on the difference in the increase of volume which they acquire by humectation [PDF]
C. Blavier
openalex +1 more source
ARTHRODESIS OF SOME OF THE SMALLER JOINTS IN THE TREATMENT OF PARALYTIC AND ACQUIRED DEFORMITIES [PDF]
, 1912 ROBERT E. SOULE
openalex +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
An investigation into the role of human capital competences and their pay-off [PDF]
Learning is possible both in school and later on when working. The learning process is thereby dependent on the context wherein it takes place. This implies that in particular three groups of competences can be distinguished.
Heijke,Hans +2 more
core +1 more source
ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
Molecular Oncology, EarlyView.In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Is Autism Inborn And Lifelong For Everyone?
Neuropsychiatric Disease and Treatment, 2019 Paul Whiteley, Kevin Carr, Paul Shattock ESPA Research, Sunderland, UKCorrespondence: Paul WhiteleyThe Robert Luff Laboratory, Unit 133i Business Innovation Centre (BIC), ESPA Research, Wearfield, Sunderland SR5 2TA, UKTel +44 191 516 6366Email paul ...
Whiteley P, Carr K, Shattock P
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