Results 171 to 180 of about 3,341,876 (297)

Inter-related mechanisms of engagement in adaptive yoga for acquired brain injury: a qualitative implementation mapping study. [PDF]

Front Health Serv
Weaver JA, Bombino-Elliott J, Pisegna J, Grove AM, Stephens JA, Schmid AA.   +5 more
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

A central-peripheral approach to gait rehabilitation in chronic acquired brain injury: robotic training and motor imagery. [PDF]

Front Rehabil Sci
Arnaudo A, Scaliti E, Damosso F, Lovera F, Rebaudengo R, Sacco K, Zettin M, Cavallo A.   +7 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Traumatic brain injury among older adults: urgent need for implementation of specific rehabilitation needs and tailored to low-middle-context

Frontiers in Human Neuroscience
Franklin Chu Buh, Franklin Chu Buh, Harry Mee, Harry Mee, Harry Mee, Fahim Anwar, Gilbert Mua Akwa, Ignatius Esene, Peter J. A. Hutchinson, Peter J. A. Hutchinson   +9 more
doaj   +1 more source

Occupational performance priorities and outcomes in long-term transitional rehabilitation for young adults with acquired brain injury. [PDF]

J Rehabil Med
Heurlin C, Schult ML, Barfai A, Rosén A, Ekholm J, Löfgren M.   +5 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Eye-Tracking Technologies for Cognitive Assessment After Acquired Brain Injury: Systematic Review. [PDF]

JMIR Rehabil Assist Technol
Calderone A, De Luca R, Corallo F, Calapai R, Mirabile A, Quartarone A, De Nunzio AM, Casella C, Calabrò RS.   +8 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Functional recovery and mortality after intensive inpatient rehabilitation for severe acquired brain injury in older adults: a retrospective cohort study. [PDF]

Front Rehabil Sci
Pingue V, Pavese C, Descalzi JI, Fiorina L, Gabba V, Bellaviti G, Nardone A.   +6 more
europepmc   +1 more source