Results 121 to 130 of about 3,156,736 (262)

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Training on the quadriceps of individuals with rheumatoid arthritis: A systematic review and meta‐analysis

Rheumatology &Autoimmunity, EarlyView.
Physical training significantly improves quadriceps strength in patients with rheumatoid arthritis. No serious adverse events were reported. Abstract Background Rheumatoid arthritis is a chronic, systemic disease in which patients can benefit from physical exercise.
Mariana Laís Boaretto, Diego Francis Saraiva Rodriguez, Dartel Ferrari de Lima, Cristiane Buzanello Donin, Alberito Rodrigo de Carvalho, Márcia Rosângela Buzanello, Gladson Ricardo Flor Bertolini   +6 more
wiley   +1 more source

Assessing physiological, behavioral and movement responses to Suprelorin implant delivery methods in free‐ranging eastern grey kangaroos Macropus giganteus

Wildlife Biology, EarlyView.
Overabundant populations of eastern grey kangaroos Macropus giganteus in peri‐urban areas pose ecological and social challenges. Current management strategies are often hindered by animal welfare and logistical concerns. This study aimed to assess stress responses of kangaroos to two contraceptive delivery methods.
Fabiola R. O. Silva, Sebastien Comte, Tamara Keeley, Maquel Brandimarti, Catherine A. Herbert   +4 more
wiley   +1 more source

Cortisol concentrations in hair are biomarkers of health status and seasonal change, but not urbanisation, in wolves

Wildlife Biology, EarlyView.
Wolves have reclaimed much of their former range in Europe, including areas with a high human footprint, yet the physiological impacts of human‐associated stressors remain poorly understood. We first examined methodological factors affecting hair cortisol concentrations (HCC) in wolves by using a ‘shave/re‐shave' design to assess hair growth rate and ...
Gwendolyn Wirobski, Carmela Musto, Rudy Brogi, Martina Lazzaroni, Rupert Palme, Yasmina Wukovich, Fanni Kertész, Ágnes Szabó, Chiara Garbarino, Marco Gobbi, Lorella Barca, Mauro Delogu, The Wolf Network, Friederike Range, Marco Apollonio, Sarah Marshall‐Pescini   +15 more
wiley   +1 more source

Fecal Glucocorticoid and Androgen Metabolites in Eastern Grey Kangaroos (Macropus giganteus) Following Environmental Relocation

Zoo Biology, EarlyView.
Fecal glucocorticoid (GCM) and androgen metabolite (AM) concentrations were monitored for 3 months following the relocation of three eastern gray kangaroos (Macropus giganteus) between zoological facilities. Both metabolites showed high concentrations during the early postrelocation period, followed by a rapid decline and stabilization, suggesting ...
Laura Menchetti, Rupert Palme, Livio Galosi, Giacomo Rossi, Elena Fraticelli, Gaia Andrea Bevinetto, Gioia Gaiot, Renato Piccinini, Raffaello Gambi, Matteo Cerquetella   +9 more
wiley   +1 more source

From allostasis to addiction: Cortisol dysregulation, daily stress and relations with 9‐year alcohol and substance use disorder severity in community adults

Addiction, EarlyView.
Abstract Background and aims Diurnal cortisol dysregulation and daily stressor severity may jointly forecast long‐term alcohol use disorder (AUD) and substance use disorder (SUD) severity, yet most evidence is cross‐sectional and relies on single cortisol indices.
Nur Hani Zainal, Natalia Van Doren
wiley   +1 more source

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.

Blood, 2015
Courtney L. Jones, Christy M. Gearheart, S. Fosmire, C. Delgado-Martín, Nikki A. Evensen, Karen L. Bride, A. Waanders, Faye M Pais, Jinhua Wang, T. Bhatla, D. Bitterman, Simone R. de Rijk, Wallace Bourgeois, Smita Dandekar, E. Park, T. Burleson, P. P. Madhusoodhan, D. Teachey, E. Raetz, M. Hermiston, M. Müschen, M. Loh, S. Hunger, Jing-Hui Zhang, M. Garabedian, C. Porter, W. Carroll   +26 more
semanticscholar   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source