Results 31 to 40 of about 9,561 (186)

Life-threatening hemorrhage from acquired hemophilia A as a presenting manifestation of prostate cancer [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
Acquired factor VIII deficiency (acquired hemophilia A) is a rare condition characterized by the acquisition of autoantibodies that affect the clotting activity of factor VIII (fVIII).
Chirag Sheth, Amandeep Gill, Sumeet Sekhon   +2 more
doaj   +1 more source

Coexistence of Acquired Hemophilia and Antiphospholipid Serology in Monoclonal Gammopathy Patient

International Medical Case Reports Journal, 2021
Nabil Belfeki, Sarra Hamrouni, Alessio Strazzulla, Sylvain Diamantis Department of Internal Medicine, Groupe Hospitalier Sud-Ile de France, Melun, 77000, FranceCorrespondence: Nabil BelfekiDepartment of Internal Medicine, Groupe Hospitalier Sud Ile de ...
Belfeki N, Hamrouni S, Strazzulla A, Diamantis S   +3 more
doaj  

Acquired hemophilia A

Hematology, 2006
Acquired hemophilia A is a rare but severe autoimmune bleeding disorder, resulting from the presence of autoantibodies directed against clotting factor VIII. The etiology of the disorder remains obscure, although approximately half of all cases are associated with other underlying conditions.
openaire   +2 more sources

Microfluidic Platform for Multiparametric Profiling of Fibrin Permeability, Fibrinolysis, and Cell Invasion

Advanced Functional Materials, EarlyView.
This paper introduces a single‐channel H‐junction microfluidic assay that profiles fibrin's evolving function in repair and thrombosis by measuring, in one ∼3 µL gel, permeability, fibrinolysis kinetics, fibroblast invasion, and clot extension in real time.
Halston Deal, Elizabeth M. Byrnes, Sanika Pandit, Halle J. Cantor, Muskan Aslam, Stacy Ban, Megan Palmisano, Rosemary Bayless, Ashley C. Brown, Michael Daniele   +9 more
wiley   +1 more source

Surgery-associated acquired hemophilia A: a report of 2 cases and review of literature

BMC Surgery, 2020
Background Acquired Hemophilia A (AHA) is a rare bleeding diathesis in patients with no previous personal or family bleeding history. The diagnosis of this disease often delays due to unfamiliarity of physicians with it, which leads to its high mortality
Umar Zeb Khan, Xiangwu Yang, Matiullah Masroor, Abdul Aziz, Hui Yi, Hai Liu   +5 more
doaj   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications

Advanced Science, EarlyView.
Classical transfection and transduction are inefficient, particularly with confluent cells and organoids, and lack cell type‐specific programmability. This study presents calcium shock (CaSh), a method that dramatically improves particle delivery into single cells, colonies, and organoids.
Nicole Vo, Lorena de Oñate, Maximillian Frank, Xian Hu, Sophie M. Blackburn, Dana V. Foss, Jasmine Villegas, Kunica Asija, Dirk Hockemeyer, Hongxia Fu, Raymond J. Monnat, Ross C. Wilson, Benjamin S. Freedman   +12 more
wiley   +1 more source

Acquired Hemophilia A Presenting as Intramuscular Hematoma

Journal of Investigative Medicine High Impact Case Reports, 2018
Acquired hemophilia A poses a clinical and diagnostic challenge. Although rare, it is still the most common acquired factor deficiency. We present a case of acquired hemophilia A diagnosed in a 71-year-old female who presented with a right thigh hematoma
Ghassan Al-Shbool MD, Anusha Vakiti MD
doaj   +1 more source

Acute Atraumatic Compartment Syndrome of the Hand Due to Acquired Hemophilia A

Journal of Hand Surgery Global Online, 2019
Acquired hemophilia A (factor VIII inhibitor) is a rare idiopathic disease with a high rate of morbidity and mortality. We report the case of an 83-year-old woman who presented with atraumatic compartment syndrome of the right hand resulting from ...
Daniel Walder, MD, Thuan Ly, MD, Claudia Meuli-Simmen, MD, Mario Bargetzi, MD, Flavien Mauler, MD   +4 more
doaj   +1 more source

The problem of acquired hemophilia [PDF]

Blood, 2015
In this issue of Blood , Andreas Tiede et al report the results of a German, Austrian, and Swiss registry (GTH-AH study) of acquired hemophilia and identify prognostic factors that may guide the choice of immunosuppressive treatment (IST) to eradicate the autoantibody contributing to the outcome ...
Francesco Baudo, Francesco de Cataldo
openaire   +2 more sources