Results 1 to 10 of about 19,249 (228)

Emicizumab in the treatment of acquired hemophilia A: A Two-Center experience [PDF]

Annals of Hematology
Emicizumab is a FVIII mimetic antibody used in the treatment of inherited hemophilia A that could potentially be used in acquired hemophilia A (AHA) to achieve hemostasis and shorten hospital stay while reducing bypass therapies. We report on 12 cases of
Malcolm Su, Sean Yates, Melissa Sanchez, Yu-Min Shen   +3 more
doaj   +2 more sources

Orthopedic manifestations of acquired hemophilia: a case report on uncontrolled bleeding and progressive swelling post-phlebotomy- should fasciotomy be considered? [PDF]

BMC Musculoskeletal Disorders
Background Acquired hemophilia A (AHA) is a rare bleeding disorder caused by autoantibodies against clotting factors, often resulting in spontaneous bleeding or bleeding after minor trauma, potentially leading to Acute Compartment Syndrome (ACS ...
Parham Talebian, Mohammad Soleimani, Mahsa Mottahedi, Elham Nazar, Parmida Shahbazi   +4 more
doaj   +2 more sources

Postpartum acquired hemophilia presenting as compartment syndrome: a diagnostic challenge in the emergency department [PDF]

International Journal of Emergency Medicine
Background Acquired hemophilia A is an uncommon but potentially life-threatening bleeding disorder caused by autoantibodies against factor VIII. It can be associated with autoimmune disease, malignancy, or pregnancy. Case report We describe a 31-year-old
Waseem Mujahed, Ahmad Nama, Joseph Kalish, Qasim Nimer, Barry Hahn, Evan Avraham Alpert   +5 more
doaj   +2 more sources

Concomitant Acquired Hemophilia A and Acquired Von Willebrand Syndrome from Distinctive Autoantibodies: Case Report [PDF]

Hematology Reports
Background and Clinical Significance: Acquired hemophilia A (AHA) and acquired von Willebrand syndrome (AVWS) are rare bleeding disorders that do not often present concurrently.
Richard Yu, Mackenzie Bowman, Arnaud Bonnefoy, Paula James, Chai W. Phua   +4 more
doaj   +2 more sources

Acquired hemophilia A: a case report and review of the literature [PDF]

Journal of Medical Case Reports
Background Acquired hemophilia A is a rare autoimmune disease characterized by inhibitory antibodies against coagulation factor VIII, leading to an increased risk of bleeding. The relevance of this case lies in its high associated morbidity and mortality,
Juan-Alfonso Perotti-Abad, Álvaro Cabezas-Corado, Luis Astolfi-Labrador, María Baus-Domínguez, Guillermo Machuca-Portillo, María-Ángeles Serrera-Figallo, Daniel Torres-Lagares   +6 more
doaj   +2 more sources

Acquired Hemophilia A Secondary to an Immune Checkpoint Inhibitor: A Case Report

JTO Clinical and Research Reports, 2022
We report a case of a patient with extensive-stage SCLC who developed acquired hemophilia A during maintenance atezolizumab therapy. The patient initially presented with asymptomatic anemia, a prolonged acquired prothrombin time, and factor VIII (FVIII ...
James Fletcher, MBBS, Robert Bird, MBBS, Andrew J.W. McLean, MBBS, Kenneth O’Byrne, MD, Wen Xu, MBBS   +4 more
doaj   +1 more source

Surgery-associated acquired hemophilia A: a report of 2 cases and review of literature

BMC Surgery, 2020
Background Acquired Hemophilia A (AHA) is a rare bleeding diathesis in patients with no previous personal or family bleeding history. The diagnosis of this disease often delays due to unfamiliarity of physicians with it, which leads to its high mortality
Umar Zeb Khan, Xiangwu Yang, Matiullah Masroor, Abdul Aziz, Hui Yi, Hai Liu   +5 more
doaj   +1 more source

A Rare Case of Acquired Hemophilia A in Adolescents and Young Adults

Clinical Pediatric Hematology-Oncology, 2022
Acquired hemophilia A (AHA) is a rare bleeding disorder, especially in adolescents and young adults (AYAs) attributable to the development of autoantibodies against coagulation factor VIII (FVIII). AHA diagnosis is difficult; patients lack any history of
Min Jeong Lee, Young Shil Park
doaj   +1 more source

Acquired hemophilia A and plasma cell neoplasms: a case report and review of the literature

Journal of Medical Case Reports, 2020
Background Acquired hemophilia A is a rare autoimmune disease with clinically often significant bleeding diathesis resulting from circulating autoantibodies inhibiting coagulation factor VIII.
Katarzyna A. Jalowiec, Martin Andres, Behrouz Mansouri Taleghani, Albulena Musa, Martina Dickenmann, Anne Angelillo-Scherrer, Alicia Rovó, Johanna A. Kremer Hovinga   +7 more
doaj   +1 more source

Acquired hemophilia A treated with rituximab in a 62-year-old female with rheumatoid arthritis: a case-based review

Reumatismo, 2023
Acquired hemophilia A (AHA) is a rare autoimmune disorder with unpredictable hemostasis that is caused by autoantibody formation against coagulation factor VIII. AHA can occur in the context of autoimmune inflammatory rheumatic disorders. Here we report
D. Mohamadzadeh, S. Assar, F. Farsad
doaj   +1 more source