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Background Acquired hemophilia A (AHA) is a rare disease characterized by a prolonged activated partial thromboplastin time (aPTT) and the production of coagulation factor VIII inhibitors.
Hidemasa Kubo +8 more
doaj +1 more source
Acquired Hemophilia ‘A’ – An Uncommon Condition Presented with Common Manifestations
Hemophilia A is usually a congenital bleeding disorder, which manifest in males due to its X linked recessive pattern of inheritance. It commonly presents with bruises, uncontrolled bleeding post minor trauma or post circumcision, knee swelling etc ...
Deepak S. Laddhad +4 more
doaj +1 more source
Postpartum Acquired Hemophilia A. [PDF]
Acquired hemophilia A (AHA) is a bleeding disorder that occurs from aberrant production of autoantibodies that target factor VIII. The underlying cause of AHA is unclear but can present postpartum. Very few cases have reported instances of AHA coexisting with other hematological disorders, such as sickle cell trait (SCT).
Omar KO, Sebastian W, Kemper S.
europepmc +3 more sources
Immunotherapy of acquired hemophilia A. [PDF]
Abstract Acquired hemophilia A (AHA) is an autoimmune disorder characterized by the formation of autoantibodies that neutralize the function of coagulation factor VIII. Immunosuppressive therapy (IST) with glucocorticoids, cyclophosphamide, rituximab, or combinations thereof is the standard of care to suppress autoantibody formation and ...
Tiede A.
europepmc +3 more sources
WHOLE GENOME SEQUENCE OF SARS-COV-2 FROM COVID-19 ACQUIRED HEMOPHILIA PATIENT
Intro: Acquired hemophilia is an atypical pathology of SARS-CoV-2 infection, which could be variant associated. Here, we share a sequence of the SARS-CoV-2 genome from patient with COVID-19 acquired haemophilia.
U.A. Zainulabid +6 more
doaj +1 more source
Acquired hemophilia A following COVID-19 vaccine: a case report
Background In the literature, reported cases of Acquired hemophilia A (AHA) induced by COVID-19 vaccination occurred after Adenoviral Vector Deoxyribonucleic Acid (DNA)- and SARS-CoV-2 Messenger Ribonucleic acid (mRNA)-Based vaccines.
Bouselama Emna +8 more
doaj +1 more source
A case of acquired hemophilia A and bullous pemphigoid following SARS-CoV-2 mRNA vaccination
Acquired hemophilia is a rare disease resulting from autoantibodies against endogenous factor VIII (FVIII), which associates with bleeding and a high mortality rate. The pathophysiology is still unclear.
Pei-An Fu +5 more
doaj +1 more source
Inhibitors in Patients with Congenital Bleeding Disorders Other Than Hemophilia [PDF]
The most worrying complication of replacement therapy for severe hemophilia A and B is currently the occurrence of inhibitory alloantibodies against infused factor VIII and factor IX, respectively.
Franchini, Massimo +6 more
core +1 more source
Acquired hemophilia A: case report [PDF]
Case report of a 74-year-old male with acquired hemophilia A, whose etiology was not found, confirmed by hemocoagulation examinations, with clinical manifestation of protracted macroscopic hematuria, spontaneous skin and intramuscular bleedings. Treatment comprised conservative therapy administration of hemostyptics, red blood cells transfusions ...
Štefan, Sotak, Miriam, Mitníková
openaire +2 more sources
A single-center retrospective clinical study of 7 cases of acquired hemophilia A [PDF]
Objective This study aims to explore the etiology, clinical manifestations, diagnosis and treatment, and prognosis of acquired hemophilia A (AHA), and to improve the clinical understanding, diagnosis, and treatment of AHA.
QIAN Lingling, PEI Xiaoping, SUN Aihong, HEI Bin, SUN Mei
doaj +1 more source

