Results 31 to 40 of about 19,249 (228)

A Case of Acquired Hemophilia A and Congenital Hemophilia B

Cureus, 2022
Congenital hemophilia B is a rare, inherited X-linked bleeding disorder caused by a deficiency of factor IX (FIX). Acquired hemophilia A is a rare, acquired bleeding disorder which presents as new onset bleeding in older adults due to the development of autoantibodies against factor VIII (FVIII).
Fortier, Julia C, Pang, Shiyi S, Amofa-Ho, Sam, Harris, Neil S, Zumberg, Marc   +4 more
openaire   +2 more sources

Hemophilia A yang Didapat: Suatu Tinjauan tentang Diagnosis dan Manajemen

WMJ (Warmadewa Medical Journal), 2017
Acquired hemophilia A (AHA) is a rare acquired bleeding disorder, an autoimmune disease characterized by autoantibody directed against factor VIII.
I Made Bakta
doaj   +1 more source

The history and evolution of the clinical effectiveness of haemophilia type a treatment: a systematic review. [PDF]

, 2012
First evidence of cases of haemophilia dates from ancient Egypt, but it was when Queen Victoria from England in the 19th century transmitted this illness to her descendants, when it became known as the "royal disease".
A Aleem, A Farrugia, A Miners, A Mocroft, AL Dunn, BA Konkle, BL Evatt, BM Feldman, CA Lee, CL Poel Van der, Claudia P. Casas, D Dimichele, D Dimichele, E Berntorp, E Berntorp, E Santagostino, Hector E. Castro, J Astermark, J Goudemand, J Oldenburg, J Stachnik, J Tusell, J Wight, Juan David Rueda, K Porter, L Valentino, L Valentino, LM Aledort, M Carcao, M Carcao, M Depka Von, M Franchini, M Lloyd, M Makris, María Fernanda Briceño, MD Carcao, MV Ragni, P Petrini, PM Mannucci, PM Mannucci, R Prabhu, S Royal, SA Larsson, SC Darby, SC Gouw, T Wong, TL Chorba, VS Blanchette, WK Hoots   +48 more
core   +2 more sources

Acquired hemophilia A: A concise review [PDF]

American Journal of Hematology, 2005
AbstractAcquired hemophilia A is a rare but severe autoimmune bleeding disorder. It is more frequent in the elderly and results from the presence of autoantibodies directed against clotting factor VIII. In this review, we briefly report on the present state of knowledge regarding acquired hemophilia A, analyzing its epidemiology, pathogenesis ...
Massimo, Franchini, Giorgio, Gandini, Tiziana, Di Paolantonio, Guglielmo, Mariani   +3 more
openaire   +2 more sources

Literature review and clinical observation of acquired idiopathic hemophilia with a new missense mutation in the factor VIII gene (His2026Arg) [PDF]

Терапевтический архив, 2018
The article provides review of possible mechanisms of inhibitor coagulopathies, in particular of acquired hemophilia A. This pathology is an extremely rare disease occurring in 1-2 cases in 1 million per year. In the present study we provide data for two
V I ERSHOV, I Yu GADAEV, D A BUDANOVA, F G PERINA, V L SURIN, V V SALOMASHKINA, O S PSHENICHNIKOVA, N I ZOZULYA   +7 more
doaj   +1 more source

Perinatal Gene Transfer to the Liver [PDF]

, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM, Chan, JK, Howe, SJ, McKay, TR, Rahim, AA, Waddington, SN, Ward, NJ   +6 more
core   +1 more source

Acquired hemophilia A in a patient treated by Ginkgo‐dipyridamolum

Clinical Case Reports, 2017
Key Clinical Message Acquired hemophilia A might be caused by Ginkgo‐dipyridamolum especially by Ginkgo, and it was successfully treated with hemostasis and immune‐suppression therapy including methylprednisolone and cyclophosphamide.
Jinbo Liu, Hongyu Wang, Guangyun Shang, Lichun Wang, Hongwei Zhao, Huan Liu   +5 more
doaj   +1 more source

Sex significantly influences transduction of murine liver by recombinant adeno-associated viral vectors through an androgen-dependent pathway. [PDF]

, 2003
A systematic evaluation of the influence of sex on transduction by recombinant adeno-associated viral vector (rAAV) indicated that transgene expression after liver-targeted delivery of vector particles was between 5- to 13-fold higher in male mice ...
Davidoff, AM, Nathwani, AC, Ng, CYC, Spence, Y, Zhou, J   +4 more
core   +1 more source

Spontaneous bleeding in a patient with malignant lymphoma: A case of acquired hemophilia [PDF]

, 2000
Background: Acquired hemophilia is a rare condition which can be associated with lymphoproliferative disease. Case Report: Eleven yea rs after the diagnosis of immunocytoma had been made, a 72-year-old man developed a high-titer factor VIII inhibitor. At
Brack, N., Geiersberger, U., Gesierich, Wolfgang, Hartenstein, R., Munker, Reinhold, Pohlmann, H.   +5 more
core   +1 more source

Acquired Hemophilia A [PDF]

Hematology & Transfusion International Journal, 2017
Acquired hemophilia A AHA is a rare but potentially life threatening bleeding disorder caused by the development of auto antibodies against circulating factor VIII Age distribution is bimodal with a first peak occurring among young women in postpartum period and a second major peak among elderly patients Fifty percent of cases are idiopathic ...
openaire   +1 more source