Modeling Nosocomial Disease Outbreaks using a Combined Differential Equations and Agent Based-Modeling Approach [PDF]
A nosocomial infection is an infection that a patient develops while in a hospital or healthcare related setting, also known as a hospital acquired infection (HAI).This project has two foci: firstly to model a HAI within an individual, then secondly to ...
FitzGerald, Cody Eion
core +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Modulation of Plant Defense System in Response to Microbial Interactions
At different stages throughout their life cycle, plants often encounter several pathogenic microbes that challenge plant growth and development. The sophisticated innate plant immune system prevents the growth of harmful microbes via two interconnected ...
Resna Nishad+4 more
doaj +1 more source
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke+2 more
wiley +1 more source
The Emerging Role of Pattern Recognition Receptors in the Pathogenesis of Malaria
Despite a global effort to develop an effective vaccine, malaria is still a significant health problem. Much of the pathology of malaria is immune mediated. This suggests that host immune responses have to be finely regulated.
Parisa Kalantari
doaj +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The association between the immune system and malignancy : a brief review [PDF]
The immune system has evolved to protect the host from a universe of pathogenic microbes and eliminate toxic substances from the body. It is an interactive network of lymphoid organs, cells, humoral factors, and cytokines.
Abrahamse, H., Ayuk, S.M
core
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang+2 more
wiley +1 more source
A comparative study of multimodal magnetic resonance in the differential diagnosis of acquired immune deficiency syndrome related primary central nervous system lymphoma and infection [PDF]
Jing Li+5 more
openalex +2 more sources
Imbalance of Peripheral Lymphocyte Subsets in Patients With Ankylosing Spondylitis: A Meta-Analysis
Ankylosing spondylitis is a complicated consequence of genetic predisposition and environmental factors. Enthesitis is believed to be the hallmark of ankylosing spondylitis, and the chronic inflammatory state of this disease is perpetuated by the ...
Dong Liu+3 more
doaj +1 more source