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Innate immune system and preeclampsia [PDF]
Frontiers in Immunology, 2014 Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda +3 more
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The innate immune system in transplantation [PDF]
Seminars in Immunology, 2011 The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Oberbarnscheidt, Martin H. +2 more
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CNS remyelination and the innate immune system [PDF]
Frontiers in Cell and Developmental Biology, 2016 A misguided inflammatory response is frequently implicated in myelin damage. Particularly prominent among myelin diseases, multiple sclerosis (MS) is an autoimmune condition, with immune–mediated damage central to its aetiology.
Christopher E McMurran +3 more
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The Innate Immune System in Alzheimer’s Disease [PDF]
International Journal of Cell Biology, 2013 Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloid β (Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (
Allal Boutajangout, Thomas Wisniewski
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Control of adaptive immunity by the innate immune system [PDF]
Nature Immunology, 2015 Microbial infections are recognized by the innate immune system both to elicit immediate defense and to generate long-lasting adaptive immunity. To detect and respond to vastly different groups of pathogens, the innate immune system uses several recognition systems that rely on sensing common structural and functional features associated with different
Akiko, Iwasaki, Ruslan, Medzhitov
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The interaction of innate immune and adaptive immune system
MedCommThe innate immune system serves as the body's first line of defense, utilizing pattern recognition receptors like Toll‐like receptors to detect pathogens and initiate rapid response mechanisms.
Ruyuan Wang +12 more
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Microorganisms, 2021 Vibrosis is one of the major threats in aquaculture farming, and due to the increasing antimicrobial resistance of different Vibrio species, there is an urgent need to replace conventional treatments with more sustainable solutions.
Barbara Rossi +6 more
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Innate immune sensors for detecting nucleic acids during infection
Journal of Laboratory Medicine, 2022 Innate immune receptors detect nucleic acids, such as viruses, and initiate an immune response by secreting interferon (IFN) and regulating IFN-stimulated genes (ISG).
Ghoreshi Zohreh-alsadat +4 more
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Innate Immune Responses to Influenza Virus Infections in the Upper Respiratory Tract
Viruses, 2021 The innate immune system is the host’s first line of immune defence against any invading pathogen. To establish an infection in a human host the influenza virus must replicate in epithelial cells of the upper respiratory tract. However, there are several
Edin J. Mifsud, Miku Kuba, Ian G. Barr
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Evolution of innate immune systems* [PDF]
Biochemistry and Molecular Biology Education, 2005 AbstractInnate immunity is the oldest form of defense and is found to some degree in all species. It predates the adaptive immune system, consisting of antibodies, B cells, T cells, and the major histocompatibility antigens. These are found only in higher vertebrates and have been the focus of the majority of immunological research, particularly in ...
Jakob, Suckale +2 more
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