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Toll-like receptors (TLR) are a class of proteins that play a key role during the first step of interaction between the pathogens and innate immune system.
Aycan Kundakcı, Arash Pirat
doaj +1 more source
Toll like receptors agonists-based nanomedicines as veterinary immunotherapies
Many infections affecting animals enter across mucosa, needing of secretory immunity to reject the disease; protection against some pathogens must be early, fast, and specifically elicited, while from others must be wide enough to fight against ...
Federico L Parra +2 more
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Toll-like receptors in cardiac hypertrophy
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Yanan Zhang +23 more
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Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation [PDF]
Diabetic cardiomyopathy is defined as a ventricular dysfunction initiated by alterations in cardiac energy substrates in the absence of coronary artery disease and hypertension.
Egido, Jesús +4 more
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Toll-like Receptors in Viral Encephalitis
Viral encephalitis is a rare but serious syndrome. In addition to DNA-encoded herpes viruses, such as herpes simplex virus and varicella zoster virus, RNA-encoded viruses from the families of Flaviviridae, Rhabdoviridae and Paramyxoviridae are important ...
Olivia Luise Gern +6 more
doaj +1 more source
Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation [PDF]
Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Albarracín, Leonardo Miguel +13 more
core +1 more source
Toll-like receptors in cerebral ischemic inflammatory injury [PDF]
Cerebral ischemia triggers acute inflammation, which has been associated with an increase in brain damage. The mechanisms that regulate the inflammatory response after cerebral ischemia are multifaceted.
Yan-Chun Wang, Sen Lin, Qing-Wu Yang
core +1 more source
Emerging role of endosomal toll-like receptors in rheumatoid arthritis [PDF]
Toll-like receptors (TLRs) and their downstream signaling pathways have been comprehensively characterized in innate immunity. In addition to this function, these receptors have also been suggested to be involved in the pathogenesis of many autoimmune ...
Chamberlain, Giselle +2 more
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Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]
The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael +3 more
core +2 more sources
Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. [PDF]
Bruton tyrosine kinase (BTK) links the B-cell antigen receptor (BCR) and Toll-like receptors with NF-κB. The role of BTK in primary central nervous system (CNS) lymphoma (PCNSL) is unknown.
Brennan, Cameron W. +41 more
core +2 more sources

