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Toll-Like Receptors

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2012
Toll-like receptors (TLR) are a class of proteins that play a key role during the first step of interaction between the pathogens and innate immune system.
Aycan Kundakcı, Arash Pirat
doaj   +1 more source

Toll like receptors agonists-based nanomedicines as veterinary immunotherapies

open access: yesPrecision Nanomedicine, 2020
Many infections affecting animals enter across mucosa, needing of secretory immunity to reject the disease; protection against some pathogens must be early, fast, and specifically elicited, while from others must be wide enough to fight against ...
Federico L Parra   +2 more
doaj   +1 more source

Toll-like receptors in cardiac hypertrophy

open access: yesFrontiers in Cardiovascular Medicine, 2023
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Yanan Zhang   +23 more
doaj   +1 more source

Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation [PDF]

open access: yes, 2014
Diabetic cardiomyopathy is defined as a ventricular dysfunction initiated by alterations in cardiac energy substrates in the absence of coronary artery disease and hypertension.
Egido, Jesús   +4 more
core   +4 more sources

Toll-like Receptors in Viral Encephalitis

open access: yesViruses, 2021
Viral encephalitis is a rare but serious syndrome. In addition to DNA-encoded herpes viruses, such as herpes simplex virus and varicella zoster virus, RNA-encoded viruses from the families of Flaviviridae, Rhabdoviridae and Paramyxoviridae are important ...
Olivia Luise Gern   +6 more
doaj   +1 more source

Transcriptome Modifications in Porcine Adipocytes via Toll-Like Receptors Activation [PDF]

open access: yes, 2019
Adipocytes are the most important cell type in adipose tissue playing key roles in immunometabolism. We previously reported that nine members of the Toll-like receptor (TLR) family are expressed in an originally established porcine intramuscular pre ...
Albarracín, Leonardo Miguel   +13 more
core   +1 more source

Toll-like receptors in cerebral ischemic inflammatory injury [PDF]

open access: yes, 2011
Cerebral ischemia triggers acute inflammation, which has been associated with an increase in brain damage. The mechanisms that regulate the inflammatory response after cerebral ischemia are multifaceted.
Yan-Chun Wang, Sen Lin, Qing-Wu Yang
core   +1 more source

Emerging role of endosomal toll-like receptors in rheumatoid arthritis [PDF]

open access: yes, 2014
Toll-like receptors (TLRs) and their downstream signaling pathways have been comprehensively characterized in innate immunity. In addition to this function, these receptors have also been suggested to be involved in the pathogenesis of many autoimmune ...
Chamberlain, Giselle   +2 more
core   +2 more sources

Central pathways causing fatigue in neuro-inflammatory and autoimmune illnesses [PDF]

open access: yes, 2015
The genesis of severe fatigue and disability in people following acute pathogen invasion involves the activation of Toll-like receptors followed by the upregulation of proinflammatory cytokines and the activation of microglia and astrocytes.
Berk, Michael   +3 more
core   +2 more sources

Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma. [PDF]

open access: yes, 2017
Bruton tyrosine kinase (BTK) links the B-cell antigen receptor (BCR) and Toll-like receptors with NF-κB. The role of BTK in primary central nervous system (CNS) lymphoma (PCNSL) is unknown.
Brennan, Cameron W.   +41 more
core   +2 more sources

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