Results 1 to 10 of about 196,208 (305)

Toll-Like Receptors in Neurodegeneration [PDF]

Brain Research Reviews, 2009
Innate pattern recognition receptors are implicated in first-line defense against pathogens but also participate in maintenance of tissue homeostasis and response to injury. This chapter reviews the role of Toll-like receptors (TLRs) in neuronal and glial responses that are associated with neurodegeneration.
Okun, Eitan, Griffioen, Kathleen J., Lathia, Justin D., Tang, Sung-Chun, Mattson, Mark P., Arumugam, Thiruma V.   +5 more
core   +8 more sources

Toll-Like Receptors [PDF]

Türk Yoğun Bakim Derneği Dergisi, 2012
Toll-like receptors (TLR) are a class of proteins that play a key role during the first step of interaction between the pathogens and innate immune system.
Aycan Kundakcı, Arash Pirat
doaj   +2 more sources

Toll‐like receptors in mammalian sperm [PDF]

Reproductive Medicine and Biology
Background Toll‐like receptors (TLRs) are critical components of the innate immune system and are expressed in various cells, including the reproductive system. Although their roles in female reproductive tissues such as the ovaries and uterus, including
Takashi Umehara, Takahiro Yamanaka, Masayuki Shimada   +2 more
doaj   +2 more sources

Toll-Like Receptors in Angiogenesis [PDF]

The Scientific World Journal, 2011
Toll-like receptors (TLRs) are known as pattern-recognition receptors related to the Toll protein of Drosophila. After recognition of pathogen-associated molecular patterns of microbial origin, the TLRs alert the immune system, and initiate innate and ...
Karsten Grote, Harald Schütt, Bernhard Schieffer   +2 more
doaj   +3 more sources

Toll-like receptors: versatile players in tumor [PDF]

Frontiers in Immunology
Toll-like receptors (TLRs) are a class of pattern-recognition receptors first identified for their role in detecting microbial pathogens and initiating innate immune responses.
Yang Yang, Yang Yang, Ruyu Pi
doaj   +2 more sources

Toll‐like receptors in health and disease [PDF]

MedComm
Toll‐like receptors (TLRs) are inflammatory triggers and belong to a family of pattern recognition receptors (PRRs) that are central to the regulation of host protective adaptive immune responses. Activation of TLRs in innate immune myeloid cells directs
Kunyu Wang, Hanyao Huang, Qi Zhan, Haoran Ding, Yi Li   +4 more
doaj   +2 more sources

Toll-like receptors and integrins crosstalk [PDF]

Frontiers in Immunology
Immune system recognizes invading microbes at both pathogen and antigen levels. Toll-like receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions of TLRs include cytokine and chemokine production.
Fahd Alhamdan, Fahd Alhamdan, Fahd Alhamdan, Ganchimeg Bayarsaikhan, Ganchimeg Bayarsaikhan, Ganchimeg Bayarsaikhan, Koichi Yuki, Koichi Yuki, Koichi Yuki   +8 more
doaj   +2 more sources

Toll-Like Receptors, Their Ligands, and Atherosclerosis [PDF]

The Scientific World Journal, 2011
Atherosclerosis is a disease characterized by inflammation in the arterial wall. Atherogenesis is dependent on the innate immune response involving activation of Toll-like receptors (TLRs) and the expression of inflammatory proteins.
Conrad P. Hodgkinson, Shu Ye
doaj   +2 more sources

Immunomodulatory responses of toll like receptors against 2019nCoV

Russian Open Medical Journal, 2021
The present review discusses the immune signals via toll like receptors (TLRs) against 2019nCoV. We researched using different database, up to June 18th, 2020. All the included articles were published in English language. The outcome of this review, that
Amany Sayed Maghraby
doaj   +1 more source

Toll-like receptors [PDF]

Current Biology, 2011
SummaryBeginning with the physical barrier presented by the epithelium, infectious agents such as viruses and bacteria encounter an array of cellular and molecular countermeasures that evolved within the host to resist them. Host immune responses are of two types, termed innate and adaptive.
Moresco, Eva Marie Y., LaVine, Diantha, Beutler, Bruce   +2 more
openaire   +2 more sources