Results 11 to 20 of about 196,208 (305)
Ocular surface toll like receptors in ageing
BMC Ophthalmology, 2022 Background To evaluate changes in Toll Like Receptors (TLRs) expression at the ocular surface of healthy volunteers within different age groups. Methods Fifty-one healthy volunteers were enrolled in a pilot observational study.
Antonio Di Zazzo +5 more
doaj +1 more source
Toll and Toll-like receptor signalling in development [PDF]
Development, 2018 ABSTRACT The membrane receptor Toll and the related Toll-like receptors (TLRs) are best known for their universal function in innate immunity. However, Toll/TLRs were initially discovered in a developmental context, and recent studies have revealed that Toll/TLRs carry out previously unanticipated functions in development, regulating ...
Niki Anthoney +2 more
openaire +5 more sources
Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
Journal of Hematology & Oncology, 2021 Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to current therapies and invariably recurs. Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor.
Yang Xun +3 more
doaj +1 more source
Einstein (São Paulo), 2020 Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes +5 more
doaj +2 more sources
Toll-like receptors in cardiac hypertrophy
Frontiers in Cardiovascular Medicine, 2023 Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Yanan Zhang +23 more
doaj +1 more source
Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection. [PDF]
, 2010 Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression ...
Martin Vordermeier +5 more
core +1 more source
Toll like receptors agonists-based nanomedicines as veterinary immunotherapies
Precision Nanomedicine, 2020 Many infections affecting animals enter across mucosa, needing of secretory immunity to reject the disease; protection against some pathogens must be early, fast, and specifically elicited, while from others must be wide enough to fight against ...
Federico L Parra +2 more
doaj +1 more source
Toll-like Receptors and the Eye [PDF]
Investigative Opthalmology & Visual Science, 2006 The immune response to microbial pathogens relies on both innate and adaptive components.1 The innate or immediate response is mediated in large measure by leukocytes of the blood, such as neutrophils (PMNs) and macrophages, cells that phagocytose and kill the pathogens and that concurrently coordinate additional host responses by synthesis of a wide ...
Fu-Shin X, Yu, Linda D, Hazlett
openaire +2 more sources
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
, 2005 Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Nathan W. Bartlett +24 more
core +1 more source
Toll-like Receptors in Viral Encephalitis
Viruses, 2021 Viral encephalitis is a rare but serious syndrome. In addition to DNA-encoded herpes viruses, such as herpes simplex virus and varicella zoster virus, RNA-encoded viruses from the families of Flaviviridae, Rhabdoviridae and Paramyxoviridae are important ...
Olivia Luise Gern +6 more
doaj +1 more source