Results 21 to 30 of about 5,209,524 (289)
Chicken Toll-like Receptor 3 Recognizes Its Cognate Ligand When Ectopically Expressed in Human Cells [PDF]
, 2007 Recognition of pathogens by toll-like receptors (TLRs) causes activation of signaling cascades that trigger cytokine secretion and, ultimately, innate immunity.
Kothlow, Sonja +8 more
core +1 more source
A study of the modulation of Toll-like receptor signalling in macrophages by Annexin-1 [PDF]
, 2011 PhDAnnexin-A1 (AnxA1) is an endogenous anti-inflammatory protein that has been shown to exert a protective role against the lethal effects induced by the Toll-like receptor (TLR) 4 agonist lipopolysaccharide (LPS).
Polycarpou, Anastasia
core +4 more sources
Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. [PDF]
, 2011 Innate immune activation via IL-1R or Toll-like receptors (TLR) contibutes to acute kidney injury but its role in tissue remodeling during chronic kidney disease is unclear.
Skuginna Veronika +41 more
core +1 more source
Toll-like receptors in COPD [PDF]
European Respiratory Journal, 2017 TLR4 and NODs could be potential therapeutic targets in chronic obstructive pulmonary diseasehttp://ow.ly ...
Hansbro, Philip M. +3 more
openaire +2 more sources
Toll-like receptors as adjuvant receptors
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2002 The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate immunity. At present, ligands for several of the TLRs, such as TLR2, TLR3, TLR4, TLR5, TLR6, and TLR9, have been identified.
Kaisho, Tsuneyasu, Akira, Shizuo
openaire +2 more sources
, 2005 Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders, Hans-Joachim, H-J Anders
core +1 more source
The Role of Toll Like Receptors in Hematopoietic Malignancies
Frontiers in Immunology, 2016 Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that shape the innate immune system by identifying pathogen-associated molecular patterns (PAMPS) and host-derived damage associated molecular patterns (DAMPS).
Darlene Monlish +2 more
doaj +1 more source
The role of Toll-like receptors in skin diseases [PDF]
, 2014 The innate immune system has the ability to recognize pathogens through Toll-like receptors (TLRs), which are transmembrane glycoproteins on the cell surface.
Joanna Bacharewicz +2 more
core +1 more source
The Role of Toll Like Receptors in Pregnancy [PDF]
International Journal of Fertility and Sterility, 2013 For many years, the innate immunity was of less interest than the adaptive immunity because it was perceived to have secondary importance in the functionality of the immune system.
Elham Amirchaghmaghi +5 more
doaj
Critical Care Explorations, 2021 OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD +5 more
doaj +1 more source