Results 1 to 10 of about 396,801 (209)
Toll-like receptor 5 on monocyte as a biomarker of mortality risk in patients with sepsis [PDF]
BMC Infectious DiseasesObjective To evaluate the expression of Toll-like receptor 5 on monocyte at ICU admission as a potentially novel early screening biomarker to predict the mortality risk of sepsis.
Hong Tan +4 more
doaj +2 more sources
TLR9: A Double-Dealing Toll-Like Receptor [PDF]
ImmunoTargets and TherapyMegan Nielsen,1 Daisuke Nishizaki,2,* Shumei Kato,2,* Razelle Kurzrock1 1Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA; 2Moores Cancer Center, University of California San Diego, La Jolla, CA, USA*These ...
Nielsen M +3 more
doaj +2 more sources
How Toll-like receptors influence Parkinson’s disease in the microbiome–gut–brain axis
Frontiers in Immunology, 2023 Recently, a large number of experimenters have found that the pathogenesis of Parkinson’s disease may be related to the gut microbiome and proposed the microbiome–gut–brain axis.
Ziyi Zhang +4 more
doaj +1 more source
Accelerated Calvarial Healing in Mice Lacking Toll-Like Receptor 4 [PDF]
, 2012 The bone and immune systems are closely interconnected. The immediate inflammatory response after fracture is known to trigger a healing cascade which plays an important role in bone repair.
Adam A. Kubala +7 more
core +11 more sources
Critical Care Explorations, 2021 OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD +5 more
doaj +1 more source
Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
Journal of Hematology & Oncology, 2021 Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to current therapies and invariably recurs. Despite some advancements in anti-glioma therapies, patients’ prognosis remains poor.
Yang Xun +3 more
doaj +1 more source
TLR7 Ligation Inhibits TLR8 Responsiveness in IL-27-Primed Human THP-1 Monocytes and Macrophages
Journal of Innate Immunity, 2021 Regulation of proinflammatory cytokine expression is critical in the face of single-stranded RNA (ssRNA) virus infections. Many viruses, including coronavirus and influenza virus, wreak havoc on the control of cytokine expression, leading to the ...
Natalya Odoardi +4 more
doaj +1 more source
Molecules, 2022 Toll-interleukin receptor (TIR) domains have emerged as critical players involved in innate immune signaling in humans but are also expressed as potential virulence factors within multiple pathogenic bacteria.
Eunjeong Lee +8 more
doaj +1 more source
Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk. [PDF]
PLoS ONE, 2015 Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the ...
Vesa-Matti Pohjanen +11 more
doaj +1 more source
The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor. [PDF]
, 2008 Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids; however, these responses come at the cost of potential autoimmunity owing to inappropriate recognition of self nucleic acids.
Barton, Gregory M +6 more
core +5 more sources