Results 21 to 30 of about 233,084 (265)
Toll-like receptors as adjuvant receptors
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2002 The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate immunity. At present, ligands for several of the TLRs, such as TLR2, TLR3, TLR4, TLR5, TLR6, and TLR9, have been identified.
Kaisho, Tsuneyasu, Akira, Shizuo
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Toll-Like Receptors in Atherosclerosis [PDF]
International Journal of Molecular Sciences, 2013 Atherosclerosis, the leading cause of cardiovascular disease (CVD), is driven by inflammation. Increasing evidence suggests that toll-like receptors (TLRs) are key orchestrators of the atherosclerotic disease process. Interestingly, a distinct picture is being revealed for individual receptors in atherosclerosis.
Falck-Hansen, M +2 more
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Frontiers in Physiology, 2018 Innate immune signaling is essential to mount a fast and specific immune response to pathogens. Monocytes and macrophages are essential cells in the early response in their capacity as ubiquitous phagocytic cells.
Korbinian Bösl +9 more
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Einstein (São Paulo), 2020 Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes +5 more
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Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate. [PDF]
PLoS ONE, 2015 Toll-like receptor 4 and proinflammatory cytokines play a central role in the progression of nonalcoholic fatty liver disease. We investigated IL-1, IL-6 and TNFα production and toll-like receptor 4 in both--obese and lean patients with non-alcoholic ...
Agnieszka Zwolak +4 more
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Japanese Journal of Clinical Immunology, 2005 Toll-like receptors (TLRs) have been revealed to recognize specific patterns of microbial components. Recognition of microbial components by TLRs initiates signal transduction pathways, triggering expression of genes, which products control innate immune responses and further instruct development of antigen-specific acquired immunity.
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Revista do Instituto de Medicina Tropical de São Paulo, 2015 There are few studies on the role of innate immune response in dermatophytosis. An investigation was conducted to define the involvement of Toll-Like Receptors (TLRs) 2 and 4 in localized (LD) and
Cristiane Beatriz de Oliveira +8 more
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Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines
FEBS Open Bio, 2023 Chronic lymphocytic leukemia (CLL) is a prototypic neoplasia in which malignant cells strongly depend on microenvironmental stimulations in the lymphoid tissues where they accumulate; leukemic cells are exposed to interaction with bystander and accessory
Miriam Meloni +4 more
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EXPRESSION FEATURES OF TOLL-LIKE RECEPTOR 2 AND TOLL-LIKE RECEPTOR 4 IN CHILDREN WITH ASTHMA
Медицинская иммунология, 2017 Currently actively discussed the role of innate immunity receptors, in particular TLRs in the immunopathogenesis of bronchial asthma (BA).The aim of our work was to study the expression of ТLR2 and TLR4 on the nasal mucosal cells and peripheral ...
L. V. Gankovskaya +7 more
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Frontiers in Immunology, 2018 Responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses.
Nathalie Guriec +6 more
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