Results 31 to 40 of about 5,866,745 (304)

Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response

open access: yesFrontiers in Physiology, 2018
Innate immune signaling is essential to mount a fast and specific immune response to pathogens. Monocytes and macrophages are essential cells in the early response in their capacity as ubiquitous phagocytic cells.
Korbinian Bösl   +9 more
doaj   +1 more source

Modulation of Toll-like receptor activity by leukocyte Ig-like receptors and their effects during bacterial infection. [PDF]

open access: yes, 2010
Toll-like receptors (TLRs) are a potent trigger for inflammatory immune responses. Without tight regulation their activation could lead to pathology, so it is imperative to extend our understanding of the regulatory mechanisms that govern TLR expression ...
Martin Vordermeier   +5 more
core   +1 more source

Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors

open access: yesEinstein (São Paulo), 2020
Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes   +5 more
doaj   +2 more sources

Toll-like Receptors and the Eye [PDF]

open access: yesInvestigative Opthalmology & Visual Science, 2006
The immune response to microbial pathogens relies on both innate and adaptive components.1 The innate or immediate response is mediated in large measure by leukocytes of the blood, such as neutrophils (PMNs) and macrophages, cells that phagocytose and kill the pathogens and that concurrently coordinate additional host responses by synthesis of a wide ...
Fu-Shin X, Yu, Linda D, Hazlett
openaire   +2 more sources

Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate. [PDF]

open access: yesPLoS ONE, 2015
Toll-like receptor 4 and proinflammatory cytokines play a central role in the progression of nonalcoholic fatty liver disease. We investigated IL-1, IL-6 and TNFα production and toll-like receptor 4 in both--obese and lean patients with non-alcoholic ...
Agnieszka Zwolak   +4 more
doaj   +1 more source

Toll-like receptor

open access: yesJapanese Journal of Clinical Immunology, 2005
Toll-like receptors (TLRs) have been revealed to recognize specific patterns of microbial components. Recognition of microbial components by TLRs initiates signal transduction pathways, triggering expression of genes, which products control innate immune responses and further instruct development of antigen-specific acquired immunity.
openaire   +3 more sources

TOLL-LIKE RECEPTORS (TLR) 2 AND 4 EXPRESSION OF KERATINOCYTES FROM PATIENTS WITH LOCALIZED AND DISSEMINATED DERMATOPHYTOSIS

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2015
There are few studies on the role of innate immune response in dermatophytosis. An investigation was conducted to define the involvement of Toll-Like Receptors (TLRs) 2 and 4 in localized (LD) and
Cristiane Beatriz de Oliveira   +8 more
doaj   +1 more source

Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines

open access: yesFEBS Open Bio, 2023
Chronic lymphocytic leukemia (CLL) is a prototypic neoplasia in which malignant cells strongly depend on microenvironmental stimulations in the lymphoid tissues where they accumulate; leukemic cells are exposed to interaction with bystander and accessory
Miriam Meloni   +4 more
doaj   +1 more source

Toll-like receptors and hypertension

open access: yesAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2014
Hypertension and associated inflammatory processes that accelerate cardiovascular damage are regulated by the innate immune system. Toll-like receptors (TLR) are major components of the innate immune system that recognize endogenous damage-associated molecular patterns to activate prominent inflammatory signaling including activation of nuclear factor-
Madhu V, Singh, François M, Abboud
openaire   +3 more sources

EXPRESSION FEATURES OF TOLL-LIKE RECEPTOR 2 AND TOLL-LIKE RECEPTOR 4 IN CHILDREN WITH ASTHMA

open access: yesМедицинская иммунология, 2017
Currently actively  discussed  the  role  of innate immunity receptors, in particular TLRs  in the immunopathogenesis of bronchial asthma (BA).The aim of our work was to study the expression of ТLR2 and TLR4 on the nasal mucosal cells and peripheral ...
L. V. Gankovskaya   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy