Results 11 to 20 of about 233,084 (265)
Role of Toll Like Receptor 4 in Alzheimer’s Disease
Frontiers in Immunology, 2020 Long-term evidence has confirmed the involvement of an inflammatory component in neurodegenerative disorders including Alzheimer’s disease (AD). This view is supported, in part, by data suggesting that selected non-steroidal anti-inflammatory drugs ...
Maria Calvo-Rodriguez +4 more
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Toll-like Receptors and the Eye [PDF]
Investigative Opthalmology & Visual Science, 2006 The immune response to microbial pathogens relies on both innate and adaptive components.1 The innate or immediate response is mediated in large measure by leukocytes of the blood, such as neutrophils (PMNs) and macrophages, cells that phagocytose and kill the pathogens and that concurrently coordinate additional host responses by synthesis of a wide ...
Fu-Shin X, Yu, Linda D, Hazlett
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Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice.
PLoS ONE, 2013 Systemic lupus erythematosus is an autoimmune disease with a high morbidity and nephritis is a common manifestation. Previous studies in murine lupus models have suggest a role for Toll-like receptor 2 and 4.
Simon J Freeley +5 more
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Role of toll like receptor 9 in developing systemic lupus erythematosus [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2023 Systemic lupus erythematosus (SLE) is a systemic autoimmune illness caused by the collapse of immunological tolerance systems. It is a multisystemic autoimmune disease.
Fatma Mostafa +2 more
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The phosphoproteome of toll‐like receptor‐activated macrophages
Molecular Systems Biology, 2010 Recognition of microbial danger signals by toll‐like receptors (TLR) causes re‐programming of macrophages. To investigate kinase cascades triggered by the TLR4 ligand lipopolysaccharide (LPS) on systems level, we performed a global, quantitative and ...
Gabriele Weintz +10 more
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Toll-like receptor signaling pathways
Frontiers in Immunology, 2014 Toll-like receptors (TLRs) play crucial roles in the innate immune system by recognizing pathogen-associated molecular patterns derived from various microbes. TLRs signal through the recruitment of specific adaptor molecules, leading to activation of the
Taro eKawai, Takumi eKawasaki
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Medical Journal of Babylon, 2023 Background and Objectives: This study aimed to examine the levels of the toll-like receptors TLR4 and TLR2 in the blood and saliva of patients with coronavirus disease-2019 (COVID-19) receiving orthodontic care in Babylon Province. Materials and Methods:
Basma Abdel Khaleq Eidan +2 more
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Toll-like receptors in COPD [PDF]
European Respiratory Journal, 2017 TLR4 and NODs could be potential therapeutic targets in chronic obstructive pulmonary diseasehttp://ow.ly ...
Hansbro, Philip M. +3 more
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Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer
Tumor Biology, 2018 Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Mira A Lanki +6 more
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Toll-Like Receptors in Angiogenesis [PDF]
The Scientific World JOURNAL, 2011 Toll-like receptors (TLRs) are known as pattern-recognition receptors related to the Toll protein ofDrosophila. After recognition of pathogen-associated molecular patterns of microbial origin, the TLRs alert the immune system, and initiate innate and adaptive immune responses.
Karsten Grote +2 more
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