Results 1 to 10 of about 17,881,864 (298)
EXPRESSION FEATURES OF TOLL-LIKE RECEPTOR 2 AND TOLL-LIKE RECEPTOR 4 IN CHILDREN WITH ASTHMA
Медицинская иммунология, 2017 Currently actively discussed the role of innate immunity receptors, in particular TLRs in the immunopathogenesis of bronchial asthma (BA).The aim of our work was to study the expression of ТLR2 and TLR4 on the nasal mucosal cells and peripheral ...
L. V. Gankovskaya +7 more
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Toll-like receptor-4 modulation for cancer immunotherapy [PDF]
Frontiers in Immunology, 2014 Toll-like receptors (TLRs) are evolutionarily conserved pattern recognition molecules. Since the discovery of the Toll pathway cascade (1, 2), our knowledge about the structure, function, and mechanics of TLRs in infectious and inflammatory conditions has increased remarkably. The role of TLR4 as a pathogen-pattern recognition receptor has been studied
Shanjana eAwasthi
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Toll-Like Receptor 4 Signaling and Drug Addiction [PDF]
Frontiers in Pharmacology, 2020 The emphasis of neuronal alterations and adaptations have long been the main focus of the studies of the mechanistic underpinnings of drug addiction. Recent studies have begun to appreciate the role of innate immune system, especially toll-like receptor ...
Ruyan Wu, Ruyan Wu, Jun-Xu Li
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Toll-Like Receptor 4 Signaling in the Trabecular Meshwork
Frontiers in Cell and Developmental Biology, 2022 Primary open-angle glaucoma is one of the leading causes of blindness worldwide. With limited therapeutics targeting the pathogenesis at the trabecular meshwork (TM), there is a great need for identifying potential new targets.
Philip Mzyk +4 more
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How Toll-like receptors influence Parkinson’s disease in the microbiome–gut–brain axis
Frontiers in Immunology, 2023 Recently, a large number of experimenters have found that the pathogenesis of Parkinson’s disease may be related to the gut microbiome and proposed the microbiome–gut–brain axis.
Ziyi Zhang +4 more
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Toll‐like receptor 4 in atherosclerosis [PDF]
Journal of Cellular and Molecular Medicine, 2007 Introduction Toll‐like receptor 4 structure and its functions TLR4 expression in atherosclerotic lesions Endothelial cells Vascular smooth muscle cells (VSMCs) Adventitial fibroblasts Dendritic cells (DCs) Macrophages Role of TLR4 in atherosclerosis TLR4 in early atherosclerotic lesion TLR4 in advanced atherosclerotic lesion TLR4 in plaque rupture ...
Li, Hongli, Sun, Baogui
openaire +2 more sources
Critical Care Explorations, 2021 OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD +5 more
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Role of Toll Like Receptor 4 in Alzheimer’s Disease
Frontiers in Immunology, 2020 Long-term evidence has confirmed the involvement of an inflammatory component in neurodegenerative disorders including Alzheimer’s disease (AD). This view is supported, in part, by data suggesting that selected non-steroidal anti-inflammatory drugs ...
Maria Calvo-Rodriguez +4 more
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Efficient of Toll‐Like Receptor 4 Knockout in Mouse Zygotes by CRISPER/Cas9
Novelty in Biomedicine, 2021 Background: Transgenic animals are genetically modified animals to create a specific trait that imitates an indication of pathogenesis in humans.
Delsuz Rezaee +3 more
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Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk. [PDF]
PLoS ONE, 2015 Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the ...
Vesa-Matti Pohjanen +11 more
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