Results 1 to 10 of about 371,093 (352)

Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway [PDF]

, 2022
Kiran Shabir, Seley Gharanei, Sophie Orton, Vanlata Patel, Parbata Chauhan, Emmanouíl Karteris, Harpal Randeva, James Brown, Ioannis Kyrou   +8 more
openalex   +1 more source

High mobility group box 1/toll-like receptor 4/myeloid differentiation factor 88 signaling promotes progression of gastric cancer

Tumor Biology, 2017
High mobility group box 1 and toll-like receptor 4/myeloid differentiation factor 88 signaling pathway have been indicated to have oncogenic effects in many cancers.
Yanqiu Yue, Tao Zhou, Yanjing Gao, Zongli Zhang, Li Li, Lin Liu, Wenna Shi, Lihui Su, Baoquan Cheng   +8 more
doaj   +1 more source

Reversion of anergy signatures in clonal CD21low B cells of mixed cryoglobulinemia after clearance of HCV viremia. [PDF]

, 2017
Hepatitis C virus (HCV) causes mixed cryoglobulinemia (MC) by driving clonal expansion of IgM+CD27+ B cells. These cells display both the features of anergy induced by continual engagement of the B cell receptor (BCR), such as high expression of ...
Casato, Milvia, Colantuono, Stefania, DEL PADRE, Martina, Fiorilli, Massimo, Marrapodi, Ramona, Mitrevski, Milica, Todi, Laura, Visentini, Marcella   +7 more
core   +1 more source

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4 [PDF]

, 2014
Ingestion of wheat, barley, or rye triggers small intestinal inflammation in patients with celiac disease. Specifically, the storage proteins of these cereals (gluten) elicit an adaptive Th1-mediated immune response in individuals carrying HLA-DQ2 or HLA-
Barisani, Donatella, Dillon, Simon, Freitag, Tobias L., Junker, Yvonne, Kelly, Ciaran P., Kim, Seong-Jun, Leffler, Daniel A., Libermann, Towia A., Schuppan, Detlef, Wieser, Herbert, Zeissig, Sebastian, Zevallos, Victor   +11 more
core   +1 more source

Modeling the interactions of bacteria and Toll-like receptor-mediated inflammation in necrotizing enterocolitis [PDF]

, 2013
Necrotizing enterocolitis (NEC) is a severe disease of the gastrointestinal tract in premature infants, characterized by a disrupted intestinal epithelium and an exaggerated pro-inflammatory response.
Afrazi, Amin, Arciero, Julia, Bard Ermentrout, G., Hackam, David, Rubin, Jonathan, Siggers, Richard, Vodovotz, Yoram   +6 more
core   +1 more source

TOLL LIKE RECEPTOR 4 (TLR4) AND DEMYELINATION

IBRO Neuroscience Reports, 2023
Estefanía Sánchez-Jiménez, Beatriz Fernández-Gómez, Esther Magan, Emma Muñoz-Sáez, Alba Macias, María Martín, David Piñeiro, Macarena Hernández-Jiménez, Alfonso Lagares, Luis Ley, Celia Oreja-Guevara, Fernando De Castro, Miguel Marchena   +12 more
doaj   +1 more source

The expression of TLR2 and TLR4 in the kidneys and heart of mice infected with Acanthamoeba spp.

Parasites & Vectors, 2020
Background Acanthamoeba spp. are cosmopolitan protozoans that cause infections in the brain, as well as extracerebral infections in the cornea, lungs and skin.
Karolina Kot, Danuta Kosik-Bogacka, Agnieszka Wojtkowiak-Giera, Agnieszka Kolasa-Wołosiuk, Natalia Łanocha-Arendarczyk   +4 more
doaj   +1 more source

Toll-like receptor 4 in experimental kidney transplantation: early mediator of endogenous danger signals [PDF]

, 2012
The role of toll-like receptors (TLRs) has been described in the pathogenesis of renal ischemia/reperfusion injury, but data on the expression and function of TLR4 during renal allograft damage are still scarce.
Banas, Bernhard, Banas, Miriam C., Bergler, Elisabeth, Bergler, Tobias, Hoffmann, Ute, Jung, Bettina, Krämer, Bernhard K., Reinhold, Stephan W.   +7 more
core   +1 more source

Lipopolysaccharide acting via toll-like receptor 4 transactivates the TGF-β receptor in vascular smooth muscle cells [PDF]

, 2022
Rizwana Afroz, Hirushi Kumarapperuma, Quang V. N. Nguyen, Raafat Mohamed, Peter J. Little, Danielle Kamato   +5 more
openalex   +1 more source

Serum soluble toll-like receptor 4 and risk for clinical severity in COVID-19 patients

Pneumonia
Toll-like receptor 4 (TLR4) signaling mediates sustained systemic inflammation in(COVID)-19 patients. We aimed to assess the serum levels of sTLR4 and sCD14 as negative regulators of Toll like receptor signaling and their association with laboratory ...
Maha E. Houssen, Marwa O. Elmaria, Dina Badr, Rasha El-Mahdy, Mayada A. Ghannam, Shaimaa El-Ashwah, May Denewer, Metwaly Ibrahim Mortada   +7 more
doaj   +1 more source