Results 31 to 40 of about 88,792,421 (301)
Iranian Journal of Allergy, Asthma and Immunology, 2019 Studies have shown that toll-like receptors (TLRs) play some important roles in reproductive processes such as ovulation, spermatogenesis, sperm capacitation, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the ...
Nasrin Sereshki +5 more
doaj +1 more source
CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo [PDF]
, 2007 Background Bacterial DNA containing motifs of unmethylated CpG dinucleotides (CpG-ODN) initiate an innate immune response mediated by the pattern recognition receptor Toll-like receptor 9 (TLR9).
Schwederski Markus +21 more
core +1 more source
Paclitaxel Induces Acute Pain via Directly Activating Toll like Receptor 4
Molecular Pain, 2015 Paclitaxel, a powerful anti-neoplastic drug, often causes pathological pain, which significantly reduces the quality of life in patients. Paclitaxel-induced pain includes pain that occurs immediately after paclitaxel treatment (paclitaxel-associated ...
Xisheng Yan +6 more
doaj +1 more source
, 2005 Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders, Hans-Joachim, H-J Anders
core +1 more source
The role of Toll-like receptor 4 (TLR-4) in wine-induced cardioprotection [PDF]
, 2012 Includes abstract.Includes bibliographical references.Moderate and chronic consumption of red wine confers cardioprotection. Melatonin, present in wine, may contribute to this cardioprotective effect. Melatonin confers cardioprotection via the activation
Albertyn, Zulfah
core +1 more source
Frontiers in Immunology, 2018 Responsiveness to invasive pathogens, clearance via the inflammatory response, and activation of appropriate acquired responses are all coordinated by innate host defenses.
Nathalie Guriec +6 more
doaj +1 more source
Homology Modeling of Toll-Like Receptor Ligand-Binding Domains [PDF]
, 2010 Toll-like receptors (TLRs) are in the front-line during the initiation of an innate immune response against invading pathogens. TLRs are type I transmembrane proteins that are expressed on the surface of immune system cells.
Wei, Tiandi
core +1 more source
Investigation of Toll-like Receptor-2, -3 and -4 Gene Expressions in Larynx Squamous Cell Carcinoma [PDF]
, 2022 Objective:Despite all the recent advancements, larynx cancer has shown no improvement in survival rates. The aim of this study was to investigate the expressions of toll-like receptor (TLR)-2, -3, and -4 genes, and determine any relationships with the ...
Çağlar Eker +10 more
core +1 more source
Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages [PDF]
, 2002 During bacterial infections, the balance between resolution of infection and development of sepsis is dependent upon the macrophage response to bacterial products.
Sweet, Matthew J +15 more
core +1 more source
Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer
Tumor Biology, 2018 Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...
Mira A Lanki +6 more
doaj +1 more source