Results 1 to 10 of about 225,120 (120)
How Toll-like receptors influence Parkinson’s disease in the microbiome–gut–brain axis
Frontiers in Immunology, 2023 Recently, a large number of experimenters have found that the pathogenesis of Parkinson’s disease may be related to the gut microbiome and proposed the microbiome–gut–brain axis.
Ziyi Zhang +4 more
doaj +1 more source
Critical Care Explorations, 2021 OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD +5 more
doaj +1 more source
Role of Toll Like Receptor 4 in Alzheimer’s Disease
Frontiers in Immunology, 2020 Long-term evidence has confirmed the involvement of an inflammatory component in neurodegenerative disorders including Alzheimer’s disease (AD). This view is supported, in part, by data suggesting that selected non-steroidal anti-inflammatory drugs ...
Maria Calvo-Rodriguez +4 more
doaj +1 more source
Efficient of Toll‐Like Receptor 4 Knockout in Mouse Zygotes by CRISPER/Cas9
Novelty in Biomedicine, 2021 Background: Transgenic animals are genetically modified animals to create a specific trait that imitates an indication of pathogenesis in humans.
Delsuz Rezaee +3 more
doaj +1 more source
Toll-Like Receptor 4 Wild Type Homozygozity of Polymorphisms +896 and +1196 Is Associated with High Gastrin Serum Levels and Peptic Ulcer Risk. [PDF]
PLoS ONE, 2015 Toll-like receptor 4 is a part of the innate immune system and recognizes Helicobacter pylori lipopolysaccharide. The goal of this study was to analyze the role of Toll-like receptor 4 polymorphisms +896 (rs4986790) and +1196 (rs4986791) in the ...
Vesa-Matti Pohjanen +11 more
doaj +1 more source
Medical Journal of Babylon, 2023 Background and Objectives: This study aimed to examine the levels of the toll-like receptors TLR4 and TLR2 in the blood and saliva of patients with coronavirus disease-2019 (COVID-19) receiving orthodontic care in Babylon Province. Materials and Methods:
Basma Abdel Khaleq Eidan +2 more
doaj +1 more source
Sequence variants of toll like receptor 4 and late-onset Alzheimer's disease.
PLoS ONE, 2012 BackgroundToll like receptor 4 (TLR4) has been related to inflammation and beta-amyloid deposition in Alzheimer's disease (AD) brain. No study has explored the association between haplotype-tagging single nucleotide polymorphisms (htSNPs) of TLR4 and AD ...
Yen-Ching Chen +6 more
doaj +1 more source
Toll-like receptor 2 or toll-like receptor 4 deficiency does not modify lupus in MRLlpr mice.
PLoS ONE, 2013 Systemic lupus erythematosus is an autoimmune disease with a high morbidity and nephritis is a common manifestation. Previous studies in murine lupus models have suggest a role for Toll-like receptor 2 and 4.
Simon J Freeley +5 more
doaj +1 more source
Gut Microbes, 2023 Intestinal contents comprise the largest repository of immunogenic ligands of microbial origin. We undertook this study to assess the predominant microbe-associated molecular patterns (MAMPs) present therein and the receptors) that mediate the innate ...
Matam Vijay-Kumar +6 more
doaj +1 more source
Toll‐like receptor 4 polymorphisms in Saudi population with cardiovascular diseases
Molecular Genetics & Genomic Medicine, 2019 Background Toll‐like receptors play a substantial role in innate immunity and the effects of TLR4 genetic variants on cardiovascular diseases are still largely unknown.
Abdelhabib Semlali +11 more
doaj +1 more source