Results 11 to 20 of about 17,602,436 (258)
Toll-like receptor 2 and Toll-like receptor 4 predict favorable prognosis in local pancreatic cancer [PDF]
Tumor Biology, 2018 Toll-like receptors play an essential role in our innate immune system and are a focus of interest in contemporary cancer research. Thus far, Toll-like receptors have shown promising prognostic value in carcinomas of the oral cavity, colon, and ovaries ...Mira A Lanki, Hanna E Seppänen, Harri K Mustonen, Camilla Böckelman, Anne T Juuti, Jaana K Hagström, Caj H Haglund +6 moredoaj +2 more sourcesAlternate transcription of the Toll-like receptor signaling cascade [PDF]
, 2006 Alternate splicing of key signaling molecules in the Toll-like receptor (Tlr) cascade has been shown to dramatically alter the signaling capacity of inflammatory cells, but it is not known how common this mechanism is. We provide transcriptional evidence Kai, Chikatoshi, Forrest, A, Schroder, K, Forrest, Alistair, Kawai, J, Kawaji, H, Wells, Christine A, Faulkner, G, Carninci, P, Hume, DA, Carninci, Piero, Grimmond, SM, Himes, SR, Lo, Sandra, Hume, David, Schroder, Kate, Taylor, D, Grimmond, Sean M, Faulkner, Geoffrey, Chalk, Alistair, Kasukawa, T, Himes, S Roy, Grimmond, Sean, Kawai, Jun, Waddell, Nic, Lo, Yu-Lan Sandra, Hayashizaki, Yoshihide, Kasukawa, Takeya, Wells, Christine, Katayama, S, Hayashizaki, Y, Chalk, Alistair M, Katayama, Shintaro, Hume, David A, Chalk, AM, Taylor, Darrin, Kawaji, Hideya, Wells, CA, Waddell, N, Lo, S, Kai, C +40 morecore +1 more sourceVaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
, 2005 Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.Nathan W. Bartlett, Geoffrey L. Smith, Haga, Ismar R, Geraldine Maloney, Bowie, Andrew G., Bartlett, Nathan W., Martina Schröder, Ismar R. Haga, Haga, Ismar R., Patrick C. Reading, Andrew G. Bowie, Fitzgerald, Katherine A, Smith, Geoffrey L, Schroeder, Martina, Reading, Patrick C, Smith, Geoffrey L., Katherine A. Fitzgerald, Bartlett, Nathan W, Julianne Stack, Maloney, Geraldine, Bowie, Andrew G, Schröder, Martina, Reading, Patrick C., Stack, Julianne, Fitzgerald, Katherine A. +24 morecore +1 more sourceFibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor [PDF]
, 2011 Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen.Saralili Dipa Robertson, Sofat, N, Nidhi Sofat, Wait, R, Robertson, SD, Wait, Robin, Robin Wait +6 morecore +1 more sourceMicroglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation. [PDF]
, 2015 Inflammatory response induced by microglia plays a critical role in the demise of neuronal populations in neuroinflammatory diseases. Although the role of toll-like receptor 4 (TLR4) in microglia's inflammatory response is fully acknowledged, little is ...Martina Svensson, Osman, AM, Salomonsson, E, Oliva Martín, María José, Annette Persson, Burguillos García, Miguel Ángel, Garcia-Quintanilla, Albert, Nikenza Viceconte, Englund, Elisabet,, Schulte, Tim, Elisabet Englund, Schulte, Tim,, Albert Garcia-Quintanilla, Kavanagh, Edel, Ahmed Mohamed Osman, Santiago, M, Joseph, Bertrand, García-Quintanilla, Alberto, Amar, Lahouari, Deierborg, Tomas,, Persson, A, Venero, Jose Luis, Blomgren, Klas, Englund, E, Leffler, H, Jose Luis Venero, Boza Serrano, Antonio, Burguillos, MA, García Quintanilla, Alberto, Martiniano Santiago, Antonio Boza-Serrano, Hakon Leffler, Joseph, B, Deierborg, Tomas, Englund, Elisabet, Persson, Annette,, Amar, L, Edel Kavanagh, Kavanagh, E, Lund University., Leffler, Hakon,, Emma Salomonsson, Venero, JL, Boza Serrano, Antonio,, Santiago, Martiniano, Venero Recio, José Luis, Amar, Lahouari,, Kavanagh, Edel T., Oliva-Martín, María J., Blomgren, K, Svensson, Martina,, Miguel Angel Burguillos, Viceconte, Nikenza, Bertrand Joseph, Salomonsson, Emma,, Oliva-Martin, Maria Jose, Svensson, Martina, Tim Schulte, Maria Jose Oliva-Martin, Osman, Ahmed Mohamed, Oliva-Martin, MJ, Boza-Serrano, A, Salomonsson, Emma, Persson, Annette, Achour, A, Garcia-Quintanilla, A, Adnane Achour, Achour, Adnane, Burguillos Garcia, Miguel, Viceconte, N, Burguillos Garcia, Miguel,, Santiago Pavón, Martiniano, Schulte, T, Tomas Deierborg, Svensson, M, Venero, José L., Klas Blomgren, Lahouari Amar, Deierborg, T, Burguillos, Miguel Angel, Leffler, Hakon, Boza-Serrano, Antonio +81 morecore +1 more sourceExtracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
Nature Communications, 2019 The enzyme nicotinate phosphoribosyltransferase (NAPRT) mediates the rate-limiting step in NAD salvage pathway starting from nicotinic acid. Here the authors show that NAPRT can be detected extracellularly, binds to Toll like receptor 4, and activates NF-Antonella Managò, Valentina Audrito, Francesca Mazzola, Leonardo Sorci, Federica Gaudino, Katiuscia Gizzi, Nicoletta Vitale, Danny Incarnato, Gabriele Minazzato, Alice Ianniello, Antonio Varriale, Sabato D’Auria, Giulio Mengozzi, Gianfranco Politano, Salvatore Oliviero, Nadia Raffaelli, Silvia Deaglio +16 moredoaj +1 more sourceDecreased Toll-like Receptor (TLR) 2 and 4 Expression in Spermatozoa in Couples with Unexplained Recurrent Spontaneous Abortion (URSA)
Iranian Journal of Allergy, Asthma and Immunology, 2019 Studies have shown that toll-like receptors (TLRs) play some important roles in reproductive processes such as ovulation, spermatogenesis, sperm capacitation, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the ...Nasrin Sereshki, Alireza Andalib, Ataollah Ghahiri, Ferdos Mehrabian, Roya Sherkat, Abbas Rezaei +5 moredoaj +1 more sourceGenetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis. [PDF]
, 2008 Despite high rates of exposure, only 5-10% of people infected with Mycobacterium tuberculosis will develop active tuberculosis (TB) disease, suggesting a significant role for genetic variation in the human immune response to this infection.Crevel, R. van, Carine Bonnard, Hazel E E Wong, Sahiratmadja Edhyana, Wong, Hazel EE, Ottenhoff, THM, Nejentsev, S., van de Vosse, Esther, Bonnard, C, Ottenhoff, T.H., Martin L Hibberd, Jeffrey S Szeszko, Ottenhoff Tom H. M., Reinout van Crevel, Balabanova, Yanina, van Crevel Reinout, Nejentsev Sergey, Seielstad, M., Ottenhoff, Tom HM, Tom H M Ottenhoff, van Crevel, Reinout, Sahiratmadja, Edhyana, Wong, H.E., Yanina Balabanova, Szeszko Jeffrey S., Hari Dass, Ranjeeta, Alisjahbana Bachti, Szeszko, Jeffrey S, Edhyana Sahiratmadja, Bonnard, Carine, Bachti Alisjahbana, Szeszko, J.S., Francis Drobniewski, Davila, Sonia, Alisjahbana, B., Hibberd, M.L., Hari Dass, R., Balabanova, Y., Alisjahbana, Bachti, van de Vosse, E, Alisjahbana, B, Bonnard Carine, Hari Dass Ranjeeta, Sonia Davila, Ranjeeta Hari Dass, Nejentsev, S, Szeszko, JS, Nejentsev, Sergey, Davila, S, Sergey Nejentsev, Seielstad Mark, Dass, Ranjeeta Hari, van Crevel, R, Bonnard, C., Dass, RH, Hibberd Martin L., Balabanova Yanina, van de Vosse Esther, Vosse, E. van de, Mark Seielstad, Seielstad, M, Hibberd, ML, Balabanova, Y, Davila, S., Drobniewski, F, Sahiratmadja, E., Davila Sonia, Drobniewski, Francis, Seielstad, Mark, Drobniewski, F., Wong, HEE, Hibberd, Martin L, Sahiratmadja, E, Esther van de Vosse, Wong Hazel E. E., Drobniewski Francis +75 morecore +3 more sources
