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The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

Cell Host and Microbe, 2020
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has had devastating global impacts and will continue to have dramatic effects on public health for years to come.
J. McKechnie, C. Blish
semanticscholar   +1 more source

ADHESION OF PATHOGENIC BACTERIA TO POLYSTYRENE, SKIN AND GUT MUCUS OF GILTHEAD SEABREAM, INFECTIOUS CAPACITY AND ANTIBIOTICS SUSCEPTIBILITY

Boletim do Instituto de Pesca, 2019
Linking proprieties of adhesion, infectious capacities and antibiotic resistance of pathogen bacteria could help to treat fish diseases. Adhesions of ten fish pathogenic bacteria were tested in microtiter plates vacant, coated with skin or gut mucus ...
Said Ben Hamed, Francisco Guardiola, Patricia Morcillo, Pilarga González-Párraga, Maria José Tavares Ranzani-Paiva, María Ángeles Esteban   +5 more
doaj   +1 more source

Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]

, 2016
Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core   +1 more source

Chronic wounds alter the proteome profile in skin mucus of farmed gilthead seabream

BMC Genomics, 2017
Background Skin and its mucus are known to be the first barrier of defence against any external stressors. In fish, skin wounds frequently appear as a result of intensive culture and also some diseases have skin ulcers as external clinical signs. However,
Héctor Cordero, Monica F. Brinchmann, Alberto Cuesta, María A. Esteban   +3 more
doaj   +1 more source

Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?

Frontiers in Aging Neuroscience, 2021
Innate immune system activation and inflammation are associated with and may contribute to clinical outcomes in people with Down syndrome (DS), neurodegenerative diseases such as Alzheimer’s disease (AD), and normal aging.
Md. Mahiuddin Ahmed, Md. Mahiuddin Ahmed, Md. Mahiuddin Ahmed, Noah R. Johnson, Noah R. Johnson, Noah R. Johnson, Timothy D. Boyd, Timothy D. Boyd, Timothy D. Boyd, Christina Coughlan, Christina Coughlan, Christina Coughlan, Heidi J. Chial, Heidi J. Chial, Heidi J. Chial, Huntington Potter, Huntington Potter, Huntington Potter   +17 more
doaj   +1 more source

libtissue - implementing innate immunity [PDF]

, 2006
In a previous paper the authors argued the case for incorporating ideas from innate immunity into articficial immune systems (AISs) and presented an outline for a conceptual framework for such systems.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

Fish Granzyme A Shows a Greater Role Than Granzyme B in Fish Innate Cell-Mediated Cytotoxicity

Frontiers in Immunology, 2019
Granzymes (Gzm) are serine proteases, contained into the secretory granules of cytotoxic cells, responsible for the cell-mediated cytotoxicity (CMC) against tumor cells and intracellular pathogens such as virus and bacteria.
Elena Chaves-Pozo, Yulema Valero, Yulema Valero, Maria Teresa Lozano, Pablo Rodríguez-Cerezo, Liang Miao, Vittorio Campo, Maria Angeles Esteban, Alberto Cuesta   +8 more
doaj   +1 more source

Host Innate Immunity Against Hepatitis Viruses and Viral Immune Evasion

Frontiers in Microbiology, 2021
Hepatitis viruses are primary causative agents of hepatitis and represent a major source of public health problems in the world. The host innate immune system forms the first line of defense against hepatitis viruses.
Chonghui Xu, Chonghui Xu, Jizheng Chen, Jizheng Chen, Xinwen Chen, Xinwen Chen   +5 more
doaj   +1 more source

'Towards a Conceptual Framework for Innate Immunity' [PDF]

, 2005
Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity.
Aickelin, Uwe, Twycross, Jamie
core   +3 more sources

The Role of the Immune System in the Pathophysiology of Essential Hypertension

Journal of Preventive, Diagnostic and Treatment Strategies in Medicine, 2022
Hypertension (HTN) is a critical worldwide health issue and an imperative risk factor for the development of cardiovascular disease and kidney disease. There are many crevices in our knowledge about the pathophysiology of HTN.
Mahsa Rekabi, Zahra Daneshmandi, Elham Sadati, Mahsa Mirzendehdel, Seyed Alireza Mahdaviani, Ali Valinejadi, Ali Akbar Velayati, Parisa Honarpisheh   +7 more
doaj   +1 more source