Results 181 to 190 of about 1,666,656 (312)

Primary Central Nervous System Lymphoma Mimicking Progressive Multifocal Leukoencephalopathy in a Patient with Acquired Immune Deficiency Syndrome

, 2014
Tomohiro Yamakawa, Katsuya Fujimoto, Ko Ebata, Junko Iwasaki, Shojiro Takahashi, Souichi Shiratori, Junichi Sugita, Takeshi Kondo, Mitsufumi Nishio, Takanori Teshima   +9 more
openalex   +2 more sources

Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β

Advanced Biology, EarlyView.
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer, Markus Michael Kramer, Miguel Baños, Merlin Moritz Grimm, Manfred Fliegauf, Bodo Grimbacher, Gerald Radziwill, Sven Rahmann, Wilfried Weber   +8 more
wiley   +1 more source

Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4₊CD25_low and CD8₊CD25_low effector T cells. [PDF]

Front Immunol
Rajmani RS, Surolia A.
europepmc   +1 more source

Paradoxical central nervous system immune reconstitution syndrome in acquired immunodeficiency syndrome-related primary central nervous system lymphoma

, 2014
Sarah M. Kranick, Priscila Gonçalves, M Stetler-Stevenson, Karen Aleman, Mark N. Polizzotto, RF Little, Robert Yarchoan, TS Uldrick   +7 more
openalex   +2 more sources

Forskolin Enhances Urokinase Plasminogen Activator Secretion and Angiogenic Activity of Xeno‐Free Cultures of Human Adipose Tissue‐Derived Stem Cells

Advanced Biology, EarlyView.
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo, Anne Therese Lauvrud, Rebecca Wiberg, Maria Brohlin, Gustav Andersson, Paul J Kingham   +5 more
wiley   +1 more source

Integrating bioinformatics and machine learning to investigate the mechanisms by which three major respiratory infectious diseases exacerbate heart failure. [PDF]

Sci Rep
Yu Y, Han Q, Zhang J, Shi J, Yuan H, Xue Y, Li Y.   +6 more
europepmc   +1 more source

Association between total immunoglobulin E and antibody responses to naturally acquired Ascaris lumbricoides infection and polymorphisms of immune system-related LIG4, TNFSF13B and IRS2 genes [PDF]

, 2009
Nathalie Acevedo, D. Mercado, Candelaria Vergara, Jorge Sánchez, Malcolm W. Kennedy, Silvia Jiménez, Antonio Fernandez, M.C. Gutiérrez, Leonardo Puerta, Luis Caraballo   +9 more
openalex   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

Mechanistic study of the immune defense function of the CRISPR1-Cas system in <i>Enterococcus faecalis</i>. [PDF]

Virulence
Tao S, Fang Y, Zheng L, Zhang H, Xu Y, Liang W.   +5 more
europepmc   +1 more source

Double‐Stranded DNA Reduces dsRNA Degradation in the Saliva and Significantly Enhanced RNAi‐Mediated Gene Silencing in Halyomorpha halys

Advanced Biology, EarlyView.
The invasive pest Halyomorpha halys causes significant crop losses requiring innovative pest control strategies such as RNA interference (RNAi). However, oral RNAi is largely ineffective in H. halys. This study shows that double‐stranded DNA (dsDNA) stabilizes dsRNA in saliva by inhibiting a highly expressed nuclease.
Venkata Partha Sarathi Amineni, Georg Petschenka, Aline Koch   +2 more
wiley   +1 more source