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Why has immune "checkpoint" therapy failed in most clinical trials? [PDF]
J Immunother CancerYang X, Chen L.
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Research note: Phosphoproteomic analysis of macrophage immunity stimulated by egg white glycopeptide. [PDF]
Poult SciHe H +11 more
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Reported Cases and Deaths of National Notifiable Infectious Diseases - China, February 2025. [PDF]
China CDC Wklyeuropepmc +1 more source
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Regulation of Acquired Immune System by Notch Signaling
International Journal of Hematology, 2005T- and B-cells are generated from hematopoietic stem cells through lymphoid intermediates. The interplay of intrinsic and extrinsic signals determines cell fate at the branch point for T- and B-cell lineages and at the post-commitment stage of lymphogenesis.
Y. Minato, K. Yasutomo
semanticscholar +4 more sources
Why did the acquired immune system of vertebrates evolve?
Developmental & Comparative Immunology, 2007Rapidly expanding genomic information offers important insights into the mechanisms of acquired immunity and has fostered progress in comparative immunology. However, the question of why the acquired immune system, a trait restricted to jawed vertebrates, evolved has rarely been addressed.
J. Rolff
semanticscholar +4 more sources
Do all creatures possess an acquired immune system of some sort?
BioEssays, 2014Recent findings have provided evidence for the existence of non‐vertebrate acquired immunity. We survey these findings and propose that all living organisms must express both innate and acquired immunity. This is opposed to the paradigm that only vertebrates manifest the two forms of immune mechanism; other species are thought to use innate immunity ...
Jacob Rimer, I. Cohen, N. Friedman
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Cytomegalovirus in the nervous system of patients with the acquired immune deficiency syndrome.
Brain, 1989Clinicopathological features of infection of the nervous system by cytomegalovirus (CMV) in 31 patients with the acquired immune deficiency syndrome (AIDS) are reviewed. Neuropathology was variable, ranging from rare isolated CMV inclusions in brain without associated inflammation or necrosis, to severe necrotizing ependymitis and meningoencephalitis ...
H. Vinters +6 more
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