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A series of adaptive models inspired by the acquired immune system
The acquired immune system is capable of specialising a defence of an organism in response to the its antigenic environment. This complex biological system possess interesting information processing features such as learning, memory, and the ability to generalize.
Jason Brownlee
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Role of NPR1 in Systemic Acquired Stomatal Immunity
Plants, 2023 Stomatal immunity is the primary gate of the plant pathogen defense system. Non-expressor of Pathogenesis Related 1 (NPR1) is the salicylic acid (SA) receptor, which is critical for stomatal defense. SA induces stomatal closure, but the specific role of NPR1 in guard cells and its contribution to systemic acquired resistance (SAR) remain largely ...
Qijie Guan +7 more
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The role of the acquired immune response in systemic sclerosis [PDF]
Seminars in Immunopathology, 2015 Profound alterations characterize the adaptive immune response in systemic sclerosis, and several layers of evidence support a prominent role exerted by immune cellular effectors and humoral mediators in the pathogenesis of this disease. These include (i) the presence of oligoclonal T cells in tissues undergoing fibrosis consistent with (auto)antigen ...
Chizzolini, Carlo, Boin, Francesco
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Paleo-immunology: evidence consistent with insertion of a primordial herpes virus-like element in the origins of acquired immunity. [PDF]
PLoS ONE, 2009 BACKGROUND:The RAG encoded proteins, RAG-1 and RAG-2 regulate site-specific recombination events in somatic immune B- and T-lymphocytes to generate the acquired immune repertoire.
David H Dreyfus
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Biomolecules, 2023 Although anti-programmed death-1 (PD-1) antibody therapy improves the prognosis in patients with head and neck squamous cell carcinoma (HNSCC), some patients exhibit disease progression even after showing a good response to the treatment initially ...
Yoh-ichiro Iwasa +6 more
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Effect of Nicotine on Immune System Function [PDF]
Advanced Pharmaceutical Bulletin, 2023 As a parasympathetic alkaloid and the main substance in cigarette smoke, nicotine modulates the immune system, inhibits innate and acquired immunity and is used in treating many autoimmune diseases.
leila Mahmoudzadeh +3 more
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Vaccines, 2021 Vaccination is the easiest way to stimulate the immune system to confer protection from disease. However, the inefficacy of vaccination in the elderly, especially those under nutritional control such as individuals receiving artificial nutrition after ...
Hiroyasu Akatsu
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Infections with extracellular trypanosomes require control by efficient innate immune mechanisms and can result in the destruction of the mammalian humoral immune system [PDF]
, 2020 Salivarian trypanosomes are extracellular parasites that affect humans, livestock, and game animals around the world. Through co-evolution with the mammalian immune system, trypanosomes have developed defense mechanisms that allow them to thrive in blood,
Magez, Stefan +3 more
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Evolutionary trade-off between innate and acquired immune defences in birds
Frontiers in Zoology, 2023 Background The development, maintenance, and use of immune defences are costly. Therefore, animals face trade-offs in terms of resource allocation within their immune system and between their immune system and other physiological processes.
Piotr Minias +2 more
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Intracellular infection and immune system cues rewire adipocytes to acquire immune function
Cell Metabolism, 2022 Adipose tissue (AT) plays a central role in systemic metabolic homeostasis, but its function during bacterial infection remains unclear. Following subcutaneous bacterial infection, adipocytes surrounding draining lymph nodes initiated a transcriptional response indicative of stimulation with IFN-γ and a shift away from lipid metabolism toward an ...
Caputa, George +24 more
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