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Prospects for the development of adaptive medical immunology
Медицинская иммунология, 2023 The processes of adaptation of the human immune system to negative internal and external influences, including stress, infectious, environmental factors, are controlled by the neuroimmunoendocrine complex (NIEC). The normal functioning of the NIEC is the
I. V. Nesterova, N. S. Tataurschikova
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The role of HLA genotypes in understanding the pathogenesis of severe COVID-19
Egyptian Journal of Medical Human Genetics, 2023 The coronavirus disease 2019 (COVID-19) pandemic has caused human tragedy through the global spread of the viral pathogen SARS-CoV-2. Although the underlying factors for the severity of COVID-19 in different people are still unknown, several gene ...
Fatemeh Arab +4 more
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Study on hypoxia-inducible factor and its roles in immune system
Immunological Medicine, 2021 The Hypoxia-Inducible Factor-1 (HIF-1) is a dimeric protein complex that plays a significant role in responding to low oxygen or hypoxia concentrations.
Ali Asghar Kiani +5 more
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INFECTION-ACQUIRED VERSUS VACCINE-INDUCED IMMUNITY AGAINST COVID-19
Central Asian Journal of Medical Hypotheses and Ethics, 2021 The course of COVID-19 depends on a dynamic interplay between SARS-CoV-2 and the host's immune system. Although it is an emerging global health issue, little is known about the specificity, safety, and duration of the immunity elicited by the virus. This
Tsvetelina Velikova
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Role of NPR1 in Systemic Acquired Stomatal Immunity
Plants, 2023 Stomatal immunity is the primary gate of the plant pathogen defense system. Non-expressor of Pathogenesis Related 1 (NPR1) is the salicylic acid (SA) receptor, which is critical for stomatal defense. SA induces stomatal closure, but the specific role of NPR1 in guard cells and its contribution to systemic acquired resistance (SAR) remain largely ...
Qijie Guan +7 more
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Intracellular infection and immune system cues rewire adipocytes to acquire immune function
Cell Metabolism, 2022 Adipose tissue (AT) plays a central role in systemic metabolic homeostasis, but its function during bacterial infection remains unclear. Following subcutaneous bacterial infection, adipocytes surrounding draining lymph nodes initiated a transcriptional response indicative of stimulation with IFN-γ and a shift away from lipid metabolism toward an ...
Caputa, George +24 more
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Paleo-immunology: evidence consistent with insertion of a primordial herpes virus-like element in the origins of acquired immunity. [PDF]
PLoS ONE, 2009 BACKGROUND:The RAG encoded proteins, RAG-1 and RAG-2 regulate site-specific recombination events in somatic immune B- and T-lymphocytes to generate the acquired immune repertoire.
David H Dreyfus
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Vaccines, 2021 Vaccination is the easiest way to stimulate the immune system to confer protection from disease. However, the inefficacy of vaccination in the elderly, especially those under nutritional control such as individuals receiving artificial nutrition after ...
Hiroyasu Akatsu
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Effect of Nicotine on Immune System Function [PDF]
Advanced Pharmaceutical Bulletin, 2023 As a parasympathetic alkaloid and the main substance in cigarette smoke, nicotine modulates the immune system, inhibits innate and acquired immunity and is used in treating many autoimmune diseases.
leila Mahmoudzadeh +3 more
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Biomolecules, 2023 Although anti-programmed death-1 (PD-1) antibody therapy improves the prognosis in patients with head and neck squamous cell carcinoma (HNSCC), some patients exhibit disease progression even after showing a good response to the treatment initially ...
Yoh-ichiro Iwasa +6 more
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