Probiotics and probiotic-based vaccines: A novel approach for improving vaccine efficacy [PDF]
Frontiers in Medicine, 2022 Vaccination is defined as the stimulation and development of the adaptive immune system by administering specific antigens. Vaccines' efficacy, in inducing immunity, varies in different societies due to economic, social, and biological conditions. One of
Nesa Kazemifard +3 more
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Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity [PDF]
Nature Immunology, 2021 Controlled human infections provide opportunities to study the interaction between the immune system and malaria parasites, which is essential for vaccine development. Here, we compared immune signatures of malaria-naive Europeans and of Africans with lifelong malaria exposure using mass cytometry, RNA sequencing and data integration, before and 5 and ...
De Jong +26 more
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Introduction to immunology and immune disorders [PDF]
Allergy, Asthma & Clinical ImmunologyThe body has a collection of physical barriers to prevent infection, but once these are overcome, we rely on our immune systems to protect us against a wide variety of infections. The complex mechanisms through which this is achieved are grouped into two
Jean S. Marshall +5 more
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Structural aspects of molecular recognition in the immune system. Part I: Acquired immunity (IUPAC Technical Report) [PDF]
Pure and Applied Chemistry, 2014 Abstract Humoral immunity allows the body to mount a defense against pathogens and foreign substances, and to respond with memory to subsequent exposures. The molecular participants may also recognize self-structures, leading to attack on the body and autoimmune disease. The main players in humoral immunity are antibody-producing B lymphocytes, and
Douglas M. Templeton, Kerstin Moehle
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New Aspect of Immune System: Innate Immunity and Acquired Immunity
Journal of the Japanese Association for Infectious Diseases, 2006 Recently, it has been turned out that our internal defense system is composed of two distinct components; innate/natural immune system and acquired/adaptive immune system. The former innate immunity is principally located at the surface area such as skin and mucosal compartment, while the latter acquired immunity is observed mainly in the circulating ...
Hidemi Takahashi
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The specialized iNKT cell system recognizes glycolipid antigens and bridges the innate and acquired immune systems with potential applications for cancer therapy [PDF]
International Immunology, 2009 Invariant NKT (iNKT) cells bridge innate and acquired immunity and play an important role in both protective and regulatory responses. The nature of the response is dictated by the initial cytokine environment: interaction with IL-10-producing cells ...
M. Taniguchi +4 more
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Probiotics and Paraprobiotics in Viral Infection: Clinical Application and Effects on the Innate and Acquired Immune Systems [PDF]
Current pharmaceutical design, 2018 Recently, the risk of viral infection has dramatically increased owing to changes in human ecology such as global warming and an increased geographical movement of people and goods.
Osamu Kanauchi +3 more
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Parasites & Vectors, 2009 Insects are exposed to a wide range of microorganisms (bacteria, fungi, parasites and viruses) and have interconnected powerful immune reactions. Although insects lack an acquired immune system they have well-developed innate immune defences that allow a
Azambuja Patrícia +4 more
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The Dynamics of Dendritic Cell—Mediated Innate Immune Regulation [PDF]
Allergology International, 2007 After taking up pathogen-derived antigens, dendritic cells (DCs) leave peripheral organs and migrate into sentinel lymph nodes via afferent lymphatic vessels. During this process, they undergo maturation and produce proinflammatory cytokines, which leads
Toshiaki Ohteki
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Journal of Experimental Medicine, 1991 The multifunctional cytokine, transforming growth factor beta (TGF- beta), was identified by immunocytochemistry in the brain tissues of four patients with acquired immune deficiency syndrome (AIDS), but not in control brain tissue. The TGF-beta staining
Sharon M. Wahl +8 more
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