BackgroundCD14+ monocytes present antigens to adaptive immune cells via monocytic human leukocyte antigen receptor (mHLA-DR), which is described as an immunological synapse.
Clemens Grimm+8 more
doaj +1 more source
Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]
Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette+8 more
core +1 more source
Probiotics and probiotic-based vaccines: A novel approach for improving vaccine efficacy
Vaccination is defined as the stimulation and development of the adaptive immune system by administering specific antigens. Vaccines' efficacy, in inducing immunity, varies in different societies due to economic, social, and biological conditions. One of
Nesa Kazemifard+3 more
doaj +1 more source
Post-translational modifications of proteins in tumor immunotherapy and their potential as immunotherapeutic targets [PDF]
Protein is an important component of life. Protein modification after translation enriches the diversity of protein, regulates the structure and function of a protein, and participates in more life processes.
Yang Yang+2 more
doaj +1 more source
Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T+4 more
core +2 more sources
Getting on in Old Age: How the Gut Microbiota Interferes With Brain Innate Immunity
The immune system is crucial for defending against various invaders, such as pathogens, cancer cells or misfolded proteins. With increasing age, the diminishing immune response, known as immunosenescence, becomes evident.
Omar Mossad, Omar Mossad, Thomas Blank
doaj +1 more source
Physical activities, exercises, and their effects to the immune system
Every systems in human body correlate to maintain homeostasis. One of those systems which contribute to maintain homeostasis is the immune system. The immune system defends physiological functions against foreign substances and cancer cells through a ...
Titis Nurmasitoh
doaj +1 more source
The evolution of resistance through costly acquired immunity [PDF]
We examine the evolutionary dynamics of resistance to parasites through acquired immunity. Resistance can be achieved through the innate mechanisms of avoidance of infection and reduced pathogenicity once infected, through recovery from infection and ...
Boots M., Michael Boots, Roger G. Bowers
core +2 more sources
Early Interferon-γ Production in Human Lymphocyte Subsets in Response to Nontyphoidal Salmonella Demonstrates Inherent Capacity in Innate Cells [PDF]
Background Nontyphoidal Salmonellae frequently cause life-threatening bacteremia in sub-Saharan Africa. Young children and HIV-infected adults are particularly susceptible.
Anna E. Seeley+5 more
core +3 more sources