On the crossroad between tolerance and posttransplant lymphoma. [PDF]
, 1997 The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core +1 more source
Rational immunotherapy in the combination treatment of community-acquired pneumonia
Медицинский совет, 2015 The article analyzes the immunomodulatory therapy as part of pathogenetic treatment of community-acquired pneumonia. Immunological monitoring of patients with severe community-acquired pneumonia demonstrated a disbalance of natural resistance factors ...
G. A. Mavzyutova +4 more
doaj +1 more source
Immunological Classification of Tumor Types and Advances in Precision Combination Immunotherapy
Frontiers in Immunology, 2022 Immunity is an important physiological function acquired throughout evolution as a defense system against the invasion of pathogenic microorganisms. The immune system also eliminates senescent cells and maintains homeostasis, monitoring cell mutations ...
Xiufang Ren +5 more
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Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]
, 2018 Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico +11 more
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Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. [PDF]
, 2019 The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization.
Amir, El-Ad D +13 more
core +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Rag1-/- mutant zebrafish demonstrate specific protection following bacterial re-exposure.
PLoS ONE, 2012 BackgroundRecombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non ...
Claudia Hohn, Lora Petrie-Hanson
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Virus-Encoded Complement Regulators: Current Status
Viruses, 2021 Viruses require a host for replication and survival and hence are subjected to host immunological pressures. The complement system, a crucial first response of the host immune system, is effective in targeting viruses and virus-infected cells, and ...
Anwesha Sinha +4 more
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The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Fertility treatment in couples with seropositivity for human immunodeficiency virus: Ethics opinion
Journal of Human Reproductive Sciences, 2018 Human immunodeficiency virus results in acquired immunodeficiency syndrome which alters the immune system. The virus can be transmitted through contact with infected semen, vaginal fluids, or blood.
Duru Shah, Madhuri Patil
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