Results 61 to 70 of about 1,654,904 (325)

Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System [PDF]

open access: yes, 2013
Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows the host to recognize and incorporate short foreign DNA or RNA sequences,
Barrick, Jeffrey E.   +3 more
core   +1 more source

HGF/MET and the Immune System: Relevance for Cancer Immunotherapy

open access: yesInternational Journal of Molecular Sciences, 2018
An overactivation of hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (MET) axis promotes tumorigenesis and tumor progression in various cancer types. Research data recently evidenced that HGF/MET signaling is also involved also in
Federica Papaccio   +7 more
semanticscholar   +1 more source

Rational immunotherapy in the combination treatment of community-acquired pneumonia

open access: yesМедицинский совет, 2015
The article analyzes the immunomodulatory therapy as part of pathogenetic treatment of community-acquired pneumonia. Immunological monitoring of patients with severe community-acquired pneumonia demonstrated a disbalance of natural resistance factors ...
G. A. Mavzyutova   +4 more
doaj   +1 more source

Virus-Encoded Complement Regulators: Current Status

open access: yesViruses, 2021
Viruses require a host for replication and survival and hence are subjected to host immunological pressures. The complement system, a crucial first response of the host immune system, is effective in targeting viruses and virus-infected cells, and ...
Anwesha Sinha   +4 more
doaj   +1 more source

Wise Blood: The Principle of Overcoming in Disease and Immunity (Part 1) [PDF]

open access: yes, 2020
The immune system is an intelligently made system designed for interaction with microbes even in a perfect world; it is more than a defense. However, in a post-fall world, it is primarily a body’s defense system.
Gillen, Alan L., Huy, Keoprommony
core   +1 more source

Immunotronics - novel finite-state-machine architectures with built-in self-test using self-nonself differentiation [PDF]

open access: yes, 2002
A novel approach to hardware fault tolerance is demonstrated that takes inspiration from the human immune system as a method of fault detection. The human immune system is a remarkable system of interacting cells and organs that protect the body from ...
Bradley, D.W., Tyrrell, A.M.
core   +2 more sources

Effects of Graphene Oxide Nanoparticles on the Immune System Biomarkers Produced by RAW 264.7 and Human Whole Blood Cell Cultures

open access: yesNanomaterials, 2018
Graphene oxide nanoparticles (GONPs) have attracted a lot of attention due to their many applications. These applications include batteries, super capacitors, drug delivery and biosensing.
K. Lategan   +4 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Rag1-/- mutant zebrafish demonstrate specific protection following bacterial re-exposure.

open access: yesPLoS ONE, 2012
BackgroundRecombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non ...
Claudia Hohn, Lora Petrie-Hanson
doaj   +1 more source

Acquired Coagulopathy With Immune Checkpoint Inhibitors: An Underrecognized Association Between Inflammation and Coagulation

open access: yesJTO Clinical and Research Reports, 2020
Introduction: Immune-related adverse events affecting virtually every organ system have been described in individuals receiving immune checkpoint inhibitors.
Jacinth J. Joseph, MD   +4 more
doaj   +1 more source

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