Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System [PDF]
Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows the host to recognize and incorporate short foreign DNA or RNA sequences,
Barrick, Jeffrey E. +3 more
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B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Rag1-/- mutant zebrafish demonstrate specific protection following bacterial re-exposure.
BackgroundRecombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non ...
Claudia Hohn, Lora Petrie-Hanson
doaj +1 more source
Introduction: Immune-related adverse events affecting virtually every organ system have been described in individuals receiving immune checkpoint inhibitors.
Jacinth J. Joseph, MD +4 more
doaj +1 more source
Central nervous system involvement in patients with acquired immune deficiency syndrome (AIDS)
Central nervous system involvement occurred in 28 of 121 patients with acquired immune deficiency syndrome (AIDS). The major risk factor in this AIDS population was intravenous drug abuse (64%). A neurologic symptom or disability was the principal reason for hospitalization in 16 cases (57%).
Barbara S. Koppel +5 more
openalex +4 more sources
Modeling Nosocomial Disease Outbreaks using a Combined Differential Equations and Agent Based-Modeling Approach [PDF]
A nosocomial infection is an infection that a patient develops while in a hospital or healthcare related setting, also known as a hospital acquired infection (HAI).This project has two foci: firstly to model a HAI within an individual, then secondly to ...
FitzGerald, Cody Eion
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Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Fertility treatment in couples with seropositivity for human immunodeficiency virus: Ethics opinion
Human immunodeficiency virus results in acquired immunodeficiency syndrome which alters the immune system. The virus can be transmitted through contact with infected semen, vaginal fluids, or blood.
Duru Shah, Madhuri Patil
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Can Electromagnetic Fields Modulate Inflammation and Cell Death by Acting on the Immune System?
Programmed cell death constitutes a fundamental part of the immune response to viral infection. This process forms part of the host defence mechanism and also enables establishment of biomarkers of disease severity.
Maria Elena Lopez-Martin +4 more
doaj +1 more source
Wise Blood: The Principle of Overcoming in Disease and Immunity (Part 1) [PDF]
The immune system is an intelligently made system designed for interaction with microbes even in a perfect world; it is more than a defense. However, in a post-fall world, it is primarily a body’s defense system.
Gillen, Alan L., Huy, Keoprommony
core +1 more source

