Results 81 to 90 of about 1,654,904 (325)
Approach to Hospital-Acquired and Methicillin-Resistant Staphylococcus aureus Meningitis [PDF]
Mediterranean Journal of Infection, Microbes and Antimicrobials, 2013 Among the hospital infections, hospital-acquired central nervous system infections are quite important due to the high mortality. The pathogens that cause hospital-acquired meningitis differ according to the immune system and underlying diseases.
Selin BARDAK ÖZCEM +1 more
doaj
Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. [PDF]
, 2019 The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization.
Amir, El-Ad D +13 more
core +3 more sources
Dystonia: sparse synapses for D2 receptors in striatum of a DYT1 knock-out mouse model [PDF]
, 2020 Dystonia pathophysiology has been partly linked to downregulation and dysfunction of dopamine D2 receptors in striatum. We aimed to investigate the possible morpho-structural correlates of D2 receptor downregulation in the striatum of a DYT1 Tor1a mouse ...
Biagioni, S. +8 more
core +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Modulation of Plant Defense System in Response to Microbial Interactions
Frontiers in Microbiology, 2020 At different stages throughout their life cycle, plants often encounter several pathogenic microbes that challenge plant growth and development. The sophisticated innate plant immune system prevents the growth of harmful microbes via two interconnected ...
Resna Nishad +4 more
doaj +1 more source
The association between the immune system and malignancy : a brief review [PDF]
, 2012 The immune system has evolved to protect the host from a universe of pathogenic microbes and eliminate toxic substances from the body. It is an interactive network of lymphoid organs, cells, humoral factors, and cytokines.
Abrahamse, H., Ayuk, S.M
core
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Estudy the Effect of Breast Cancer on Tlr2 Expression in Nb4 Cell [PDF]
, 2016 Background: Breast cancer is the most common neoplasm in women and the most frequent cause of death in those between 35 and 55 years of age. All multicellular organisms have an innate immune system, whereas the adaptive or 'acquired' immune system is ...
Amirfakhri, S, Fern�ndez, N, Salimi, A
core +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source