Results 191 to 200 of about 186,959 (259)

Counteracting Influenza Virus Evolution Through the Full Spectrum of Broadly Protective Antibodies

open access: yesImmunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Despite the presence of licensed vaccines and therapeutics, influenza viruses remain a major public health concern, as they cause seasonal respiratory infections and pose a pandemic threat through the emergence of zoonotic strains. Although neutralizing antibodies elicited by seasonal vaccination constitute a primary defense against infection,
Yu Adachi, Yoshimasa Takahashi
wiley   +1 more source

Exosome‐Mediated Delivery of PROTACs for Targeted Protein Degradation in Cancer, Neurodegenerative, Infectious, and Inflammatory Diseases

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are heterobifunctional molecules that hijack the ubiquitin‐proteasome system to drive catalytic, sub‐stoichiometric degradation of disease‐associated proteins, offering a mechanistic advantage over occupancy‐driven inhibitors and access to ‘undruggable’ targets.
Sruti Bagchi Ghosh   +9 more
wiley   +1 more source
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Acquired Immunodeficiency Syndrome

Journal of Urology, 1986
AbstractThe acquired immunodeficiency syndrome (AIDS) was recognized as a distinct clinical entity in 1981 and was characterized by unexplained opportunistic infections and an aggressive form of Kaposi's sarcoma. High risk groups for contracting AIDS include homosexual men, parenteral drug users, hemophiliacs, recipients of blood and blood products ...
K V, Rolston, G P, Bodey
openaire   +4 more sources

The Acquired Immunodeficiency Syndrome

Emergency Medicine Clinics of North America, 1985
AIDS is an apparently new condition that first occurred in about 1979 and is manifested primarily by profound disturbances of T-cell immunity and unusual susceptibility to either opportunistic infections (mycobacterial, fungal, parasitic, or viral) or tumors such as Kaposi's sarcoma and lymphoma.
R S, Hansen, R D, AhLoy, R D, Meyer
openaire   +4 more sources

The Acquired Immunodeficiency Syndrome

Annals of Internal Medicine, 1983
Recently, a new epidemic illness, the acquired immunodeficiency syndrome, has dramatically emerged in the United States, Europe, and Haiti. The syndrome represents an unprecedented epidemic form of immunodeficiency involving prominent defects of the T-lymphocyte arm of the immune system.
M S, Gottlieb   +4 more
openaire   +4 more sources

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