Results 21 to 30 of about 2,228,702 (296)

Nodular pulmonary deposition disease in a patient with the acquired immunodeficiency syndrome: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Pulmonary nodules are a common cause for concern in patients with human immunodeficiency virus and acquired immunodeficiency syndrome. Most commonly, they are the result of an infection, given the patients’ immunocompromised state; however, in
Jessica N. Mezzanotte   +4 more
doaj   +1 more source

Epidemiologic and clinical characteristics of Mycobacterium tuberculosis infection in Guangxi, China, 2018-2023: a retrospective study

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundTuberculosis, caused by Mycobacterium tuberculosis, continues to be one of the leading causes of death globally. We performed a retrospective cohort study in which individuals with suspected tuberculosis were evaluated the differences between ...
Dewu Bi   +49 more
doaj   +1 more source

Rational design 2.0: transitioning from static structural biology to computational prioritization and iterative vaccine optimization for RSV

open access: yesFrontiers in Immunology
Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract disease (LRTD) in infants and older adults worldwide. Although vaccines based on the fusion (F) protein have shown progress, their efficacy remains limited by antigenic ...
Xiulong Wei   +5 more
doaj   +1 more source

Cholesterol efflux responds to viral load and CD4 counts in HIV+ patients and is dampened in HIV exposed

open access: yesJournal of Lipid Research, 2018
Cholesterol efflux (CE) capacity has been inversely associated with atherosclerosis and may provide an insight on inflammation occurring in human immunodeficiency virus (HIV) individuals. We address this by studying CE in HIV patients at different stages
Olivia Tort   +9 more
doaj   +1 more source

Application of the Chinese Version of the Pittsburgh Sleep Quality Index in People Living With HIV: Preliminary Reliability and Validity

open access: yesFrontiers in Psychiatry, 2021
Background: The Pittsburgh Sleep Quality Index (PSQI) has been a widely used instrument measuring sleep quality among people living with HIV (PLWH) in China while its psychometric properties have yet to be examined in this population.
Dong-Qin Yan   +6 more
doaj   +1 more source

Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific [PDF]

open access: yes, 1992
Krämer A, Biggar RJ, Hampl H, et al. Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. American Journal of Epidemiology.
Biggar, Robert J.   +6 more
core  

Interaction of human immunodeficiency and papilloma viruses: association with anal epithelial abnormality in homosexual men [PDF]

open access: yes, 1990
Caussy D, Goedert JJ, Palefsky J, et al. Interaction of human immunodeficiency and papilloma viruses: association with anal epithelial abnormality in homosexual men. International Journal of Cancer.
Colclough, Ginga   +12 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

open access: yesAngewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster   +13 more
wiley   +2 more sources

Genetic diversity of Brazilian isolates of feline immunodeficiency virus [PDF]

open access: yes, 2010
We isolated Feline immunodeficiency virus (FIV) from three adult domestic cats, originating from two open shelters in Brazil. Viruses were isolated from PBMC following co-cultivation with the feline T-lymphoblastoid cell line MYA-1.
HAGIWARA, M. K.   +15 more
core   +1 more source

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