Results 311 to 320 of about 197,747 (335)
Purine Metabolism and Dystonia: Perspectives of a Long‐Promised Relationship
Annals of Neurology, Volume 97, Issue 5, Page 809-825, May 2025.Purine pool imbalance in purine metabolism disorders, such as Lesch–Nyhan disease, intersects with dystonia pathogenesis. The recent discovery of gain‐of‐function IMPDH2 pathogenic variants in patients with prominent dystonic manifestations provides new insights into the link between dystonia and purinergic system defects.Ugo Sorrentino, Audrey G. O'Neill, Justin M. Kollman, Hyder A. Jinnah, Michael Zech +4 morewiley +1 more sourceCharacterization of Genetic Landscape and Novel Inflammatory Biomarkers in Patients With Adult‐Onset Still's Disease
Arthritis &Rheumatology, Volume 77, Issue 5, Page 582-595, May 2025.Objective
Adult‐onset Still disease (AOSD) is a systemic autoinflammatory disorder (AID) of unknown etiology. Genetic studies have been limited. Here, we conducted detailed genetic and inflammatory biomarker analysis of a large cohort with AOSD to investigate the underlying pathology and identify novel targets for potential treatment.Joanne Topping, Leon Chang, Fatima Nadat, James A. Poulter, Alice Ibbotson, Samuel Lara‐Reyna, Christopher M. Watson, Clive Carter, Linda P. Pournara, Jan Zernicke, Rebecca L. Ross, Catherine Cargo, Paul A. Lyons, Kenneth G. C. Smith, Francesco Del Galdo, Jürgen Rech, Bruno Fautrel, Eugen Feist, Michael F. McDermott, Sinisa Savic, on behalf of the ImmunAID Consortium +20 morewiley +1 more sourceA Multicenter, Randomized, Controlled, Clinical Trial Evaluating a Lyopreserved Amniotic Membrane in the Treatment of Venous Leg Ulcers
Health Science Reports, Volume 8, Issue 5, May 2025.ABSTRACT Background
Standard of Care (SoC) with multilayer compression therapy along with proper wound management, may not be sufficient to close all venous ulcers and needs advanced therapies. Methods
In this multicenter, prospective, randomized, controlled, open‐label trial, 351 patients were screened, 200 were eligible and enrolled and were ...Yadwinder Dhillon, Lena Levine, Gregory Tovmassian, Alexander Reyzelman, Francisco Perez‐Clavijo, Francis Wodie, Shawn Cazzell, Allan Grossman, Lesly Robinson, Felix Sigal, Robert S Kirsner, Mher Vartivarian, Molly Saunders, Jaideep Banerjee +13 morewiley +1 more sourceOxidative Stress in People Living With HIV: Are Diverse Supplement Sources the Solution?
Health Science Reports, Volume 8, Issue 5, May 2025.ABSTRACT Background and Aim
Antiretroviral therapy (ART) has reduced human immunodeficiency virus (HIV)/AIDS to a manageable chronic condition even though no cure exists. Despite ART control, latent HIV infection results in failed memory CD4 T‐cell responses, immune overactivation, inflammation, oxidative stress, genomic instability, deoxyribonucleic ...Esimebia Adjovi Amegashie, Ruth Oyawole Sikeola, Emmanuel Ayitey Tagoe, Elijah Paintsil, Kwasi Torpey, Osbourne Quaye +5 morewiley +1 more sourceMachine‐learning analysis identifies “elite” viral controllers with increased survival and homeostatic responses in critical COVID‐19
Clinical and Translational Medicine, Volume 15, Issue 5, May 2025.Nadia García‐Mateo, Alejandro Álvaro‐Meca, Tamara Postigo, Alicia Ortega, Amanda de la de la Fuente, Raquel Almansa, Noelia Jorge, Laura González‐González, Lara Sánchez Recio, Isidoro Martínez, María Martín‐Vicente, María José Muñoz‐Gómez, Vicente Más, Mónica Vázquez, Olga Cano, Daniel Vélez‐Serrano, Luis Tamayo, José Ángel Berezo, Rubén Herrán‐Monge, Jesús Blanco, Pedro Enríquez, Pablo Ryan‐Murua, Amalia de la Martínez de la Gándara, Covadonga Rodríguez, Gloria Andrade, Elena Bustamante‐Munguira, Gloria Renedo Sánchez‐Girón, Ramón Cicuendez Ávila, Juan Bustamante‐Munguira, Wysali Trapiello, Elena Gallego Curto, Alejandro Úbeda‐Iglesias, María Salgado‐Villén, Enrique Berruguilla‐Pérez, María del Carmen del de la Torre, Estel Güell, Fernando Casadiego, Ángel Estella, María Recuerda Núñez, Juan Manuel Sánchez Calvo, Sandra Campos‐Fernández, Yhivian Peñasco‐Martín, María Teresa García Unzueta, Ignacio Martínez Varela, María Teresa Bouza Vieiro, Felipe Pérez‐García, Ana Moreno‐Romero, Lorenzo Socias, Juan López Messa, Leire Pérez Bastida, Pablo Vidal‐Cortés, Lorena del del Río‐Carbajo, Jorge del Nieto del Olmo, Estefanía Prol‐Silva, Víctor Sagredo Meneses, Noelia Albalá Martínez, Milagros González‐Rivera, José Manuel Gómez, Nieves Carbonell, María Luisa Blasco, David de de Gonzalo‐Calvo, Jessica González, Jesús Caballero, Carme Barberá, María Cruz Martín Delgado, Luis Jorge Valdivia, Caridad Martín‐López, María Teresa Nieto, Ruth Noemí Jorge García, Emilio Maseda, Ana Loza‐Vázquez, José María Eiros, Anna Motos, Laia Fernández‐Barat, Joan Casenco‐Ribas, Adrián Ceccato, Ferrán Barbé, David J. Kelvin, Jesús F. Bermejo‐Martin, Ana P. Tedim, Salvador Resino, Antoni Torres +81 morewiley +1 more sourceSome of the next articles are maybe not open access.Related searches:
