Results 71 to 80 of about 271,613 (400)

Factors Influencing the Binding of HIV‐1 Protease Inhibitors: Insights from Machine Learning Models

ChemMedChem, Accepted Article.
HIV‐1 protease inhibitors are crucial for antiviral therapies targeting acquired immunodeficiency syndrome (AIDS). Hundreds of HIV‐1 protease complexes with various ligands have been resolved and deposited in the Protein Data Bank. However, binding affinity measurements for these ligands are not always available.
Yaffa Shalit, Inbal Tuvi-Arad
wiley   +1 more source

Aplastic anemia associated to systemic lupus erythematosus in an AIDS patient: a case report

Revista Brasileira de Hematologia e Hemoterapia, 2013
Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes ...
Leonardo Rodrigues de Oliveira, Thais Camargos Ferreira, Fernando de Freitas Neves, Antonio Carlos de Oliveira Meneses   +3 more
doaj   +1 more source

Pulmonary Kaposi's Sarcoma - Initial Presentation of HIV Infection  [PDF]

Folia Medica, 2019
Kaposi’s sarcoma is the most common malignancy associated with human immunodeficiency virus. It commonly affects the skin but can present with visceral involvement, including the lungs.
Radka Komitova, Krasimira Chudomirova, Tsvetana Abadjieva   +2 more
doaj   +3 more sources

Evaluation of Potential Effects of CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Fruquintinib in Healthy Subjects

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Cytochrome P450 (CYP) 3A plays a significant role in fruquintinib metabolism in vitro. This 2‐part, 2‐period fixed‐sequence study investigated the impact of CYP3A inhibition (itraconazole) and CYP3A induction (rifampin) on the pharmacokinetics (PK) of fruquintinib and M11, its main metabolite.
Martha Gonzalez, Zhao Yang, William R Schelman, Xiaofei Zhou, Neeraj Gupta, Caly Chien   +5 more
wiley   +1 more source

Disability-adjusted life years and mortality rate attributed to unsafe sex and drug use for AIDS in the Middle East and North Africa countries

Archives of Public Health, 2020
Background The Middle East and North Africa, is one of few regions where the number of new human immunodeficiency virus infections is increasing.
Farid Najafi, Fatemeh Khosravi, Mojtaba Ghalandari, Mitra Darbandi   +3 more
doaj   +1 more source

In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.

Blood, 1995
Two unique DNA fragments were recently identified in over 90% of acquired immunodeficiency syndrome (AIDS)-related Kaposi's sarcoma tissues. Sequence analysis suggests that these fragments belong to a previously unidentified human herpesvirus, Kaposi's ...
E. Cesarman, P. Moore, Pulirarthy H. Rao, G. Inghirami, D. Knowles, Yuan Chang   +5 more
semanticscholar   +1 more source

The RNA Binding Protein Bcas2 is Required for Antibody Class Switch in Activated‐B Cells

Exploration, EarlyView.
Bcas2 recruits DHX15 and SRSF7 to form a protein complex for the splicing of CSR‐related mRNA at the 5' ss and 3' ss, generating two mature mRNA isoforms, which are ultimately translated into CSR‐related proteins. These CSR‐related proteins bind to DNA associated with antibodies, affecting the DSB repair of the relevant DNA after AID induction, thereby
Yu Chen, Siyuan Sun, Chenxu Lu, Yixuan Li, Bing Fang, Xiangfeng Tang, Xuepeng Li, Weiru Yu, Yumei Lei, Longjie Sun, Ming Zhang, Jiazeng Sun, Ping Liu, Yongting Luo, Xingwang Zhao, Jing Zhan, Libing Liu, Rong Liu, Jiaqiang Huang, Ziwei Yi, Yifei Yu, Weihan Xiao, Zheng Ding, Lei Li, Dan Su, Fazheng Ren, Changchang Cao, Ran Wang, Wenbiao Shi, Juan Chen   +29 more
wiley   +1 more source

HIV/AIDS Associated Lymphoma: Review

Blood and Lymphatic Cancer: Targets and Therapy, 2022
Ayenew Berhan,1 Biruk Bayleyegn,2 Zegeye Getaneh2 1Department of Medical Laboratory Science, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia; 2Department of Hematology and Immunohematology, School of Biomedical and Laboratory ...
Berhan A, Bayleyegn B, Getaneh Z
doaj  

Human Immunodeficiency Virus – Acquired Immunodeficiency Syndrome dengan Sarkoma Kaposi

Jurnal Kesehatan Andalas, 2018
Acquired Immunodeficiency Syndrome (AIDS) adalah infeksi yang disebabkan oleh Human Immunodeficiency Virus (HIV) yang menyebabkan suatu penyakit yang menyerang sel-sel kekebalan tubuh.
Riry Febrina Ersha, Armen Ahmad
doaj   +1 more source

Papillitis as the prominent ocular sign in Acquired Immune Deficiency Syndrome (AIDS) [PDF]

, 1989
A 29-year old homosexual presented with clinical symptoms and an immunological picture of AIDS syndrome. Ocular involvement started in August 1986 with reduction of visual acuity in the right eye rapidly progressing to amaurosis.
Blagojevic, Milan, Bonnici, Mario R., Schiro, Denis, Soler, Richard   +3 more
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