Results 81 to 90 of about 271,613 (400)

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J.   +2 more
core   +3 more sources

Bioactive Polysaccharides Targeting Gut Microbiota to Modulate Host Health: A Gear Effect Theory

Food Frontiers, EarlyView.
The “Gear Effect” mechanism of bioactive polysaccharides driving gut microbiota to modulate host health. ABSTRACT Bioactive polysaccharides are macromolecular polymers with broad biological activities. Recent evidence has highlighted their role in modulating host health primarily through interactions with gut microbiota.
Yonggan Sun, Shanshan Zhang, Junyi Yin, Shaoping Nie   +3 more
wiley   +1 more source

HIV-1 Evolutionary Patterns Associated with Metastatic Kaposi's Sarcoma during AIDS. [PDF]

, 2016
Kaposi's sarcoma (KS) in HIV-infected individuals can have a wide range of clinical outcomes, from indolent skin tumors to a life-threatening visceral cancer. KS tumors contain endothelial-related cells and inflammatory cells that may be HIV-infected. In
Barbier, Andrew E, Fogel, Gary B, Lamers, Susanna L, McGrath, Michael S, Nolan, David J, Rose, Rebecca, Salemi, Marco   +6 more
core   +4 more sources

Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency

Head &Neck, EarlyView.
ABSTRACT Background GATA2 deficiency is a rare genetic disorder associated with hematologic, infectious, and neoplastic complications. We report a case of a patient with GATA2 deficiency who developed aggressive squamous cell carcinoma (SCC) of the head and neck, an atypical manifestation of this condition.
Brejjette Aljabi, James A. Stewart, Kirk Withrow, Carissa M. Thomas   +3 more
wiley   +1 more source

Cholesterol efflux responds to viral load and CD4 counts in HIV+ patients and is dampened in HIV exposed

Journal of Lipid Research, 2018
Cholesterol efflux (CE) capacity has been inversely associated with atherosclerosis and may provide an insight on inflammation occurring in human immunodeficiency virus (HIV) individuals. We address this by studying CE in HIV patients at different stages
Olivia Tort, Tuixent Escribà, Lander Egaña-Gorroño, Elisa de Lazzari, Montserrat Cofan, Emma Fernandez, José Maria Gatell, Esteban Martinez, Felipe Garcia, Mireia Arnedo   +9 more
doaj  

Possible transmission of human immunodeficiency virus-1 infection from an elite controller to a patient who progressed to acquired immunodeficiency syndrome: a case report

Journal of Medical Case Reports, 2012
Introduction Most individuals infected with human immunodeficiency virus-1, in the absence of antiretroviral therapy, exhibit persistent virus replication and declining CD4+ cell numbers, and progress to acquired immunodeficiency syndrome within 10 years
Killian Michael, Vyas Girish N, Mehta Rochak, Young Karen, Ebrahim Osman   +4 more
doaj   +1 more source

Investigating the role of SARM1 in central nervous system

Ibrain, EarlyView.
Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang, Yuhang Shi, Jinglei Tian, Liming Tang, Fang Cao   +4 more
wiley   +1 more source

Toxoplasmic encephalitis: role of Human Leucocyte Antigens/alleles associated with rapid progression to Acquired Immunodeficiency Syndrome

Brazilian Journal of Infectious Diseases, 2016
Background/aims: The frequency of Human Leucocyte Antigens/alleles associated with rapid progression from Human Immunodeficiency Virus infection to Acquired Immunodeficiency Syndrome was evaluated in Brazilian patients with Acquired Immunodeficiency ...
Maria de Lourdes Rodrigues, Neifi Hassam Deghaide, José Fernando Figueiredo, Marcelo Bezerra de Menezes, Ana Lúcia Demarco, Eduardo Donadi, Ana Paula Fernandes   +6 more
doaj  

Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India [PDF]

, 2012
Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a
Banerjee, A, Bhattacharyya, M, Ghosh, A, Ghosh, B, Pain, S, Pande, A, Saha, S   +6 more
core   +1 more source

Challenges if HIV Treatment in Resource-Poor Countries: A Review [PDF]

, 2010
Background: The human immunodeficiency virus/acquired immunodeficiency syndrome pandemic have posed a significant public health challenge to the global community.
Muktar, HM, Obiako, OR
core   +2 more sources