Results 51 to 60 of about 3,862 (225)

Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease [PDF]

, 2018
BackgroundIn humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality.
A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Colao, A Mestron, A Piovesan, AC Dirtu, AM Pereira, B Posch, BJ Maron, BPP Meij, BR Bond, C Paige, C-Y Liu, CJL Little, CR Lamb, David B. Church, David J. Connolly, DJ Connolly, F Fracassi, G Jacobs, G Lombardi, G Lombardi, J Dal, J Gilbert, JA Myers, JK Sangster, JM Fletcher, JR Payne, JT Lie, Kieran Borgeat, LJ Wilkie, Lois Wilkie, M Galderisi, M Lesser, M Maxie Grant, M Nishiki, M Rosca, M-LL Jaffrain-Rea, MD Kittleson, ME Peterson, ME Peterson, NJ Pereira, Norelene Harrington, NS Moise, NS Moise, O Kershaw, OM Dekkers, P Menaut, PR Fox, PR Fox, PR Fox, PR Fox, PR Fox, R Baldelli, R Gostelow, R Pivonello, RC Weichselbaum, S Brown, S Fazio, S Fazio, S Fazio, S Fieffe, S Murarka, S Niessen, SJM Niessen, SJM Niessen, SJM Niessen, SK Liu, SK Liu, Stijn J. M. Niessen, SV Keyte, T Wagner, T. Rosol, Vincenzo Lionetti, Virginia Luis Fuentes, WL McGuffin   +80 more
core   +2 more sources

Luteinizing hormone receptor knockout mouse: What has it taught us?

Andrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

Diabetes Melito e Acromegalia: Interações entre Hormônio de Crescimento e Insulina

Clinical and Biomedical Research, 2011
Introdução: o hormônio de crescimento humano (GH) possui um importante papel na fisiologia do metabolismo glicêmico, lipídico e protéico. O excesso deste hormônio, como encontrado na acromegalia, induz a um estado de resistência insulínica que pode ...
Fabiola Costenaro, Ticiana da Costa Rodrigues, Daniela Fedrizzi, Marcelle Dietrich Oliveira, Mauro Antonio Czepielewski   +4 more
doaj  

In the land of giants: the legacy of José Dantas de Souza Leite

Arquivos de Neuro-Psiquiatria, 2015
The authors describe the extraordinary contribution to science made by José Dantas de Souza Leite, who graduated from the Bahia School of Medicine and trained in Prof.
Hélio A. G. Teive, Plínio M. Lima, Francisco M.B. Germiniani, César L. Boguszewski   +3 more
doaj   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Acromegalia e adenomas hipofisários: Diagnóstico e tratamento

Brazilian Neurosurgery, 2004
Acromegalia é entidade clínica resultante do aumento da produção do hormônio de crescimento (GH) em virtude da existência de um tumor hipofisário secretor deste hormônio, ou de tumores de localização extra-hipofisária com influência nas células ...
José Nazareno Pearce de Oliveira Brito, Flávio Vasconcelos Melo, Paulo Rodrigues Nunes Neto, Emerson Brandão Sousa   +3 more
doaj   +1 more source

Proteína moduladora de la actividad del receptor de aril hidrocarburos (AIP): genética, bioquímica e impacto clínico

Repertorio de Medicina y Cirugía, 2021
El gen AIP (proteína moduladora de la actividad del receptor de aril hidrocarburos) se localiza en la región 11q13.2 y codifica para una proteína de 330 aminoácidos que interactúa con el factor de transcripción AhR (receptor para aril hidrocarburos). Las
Andres Florez Romero , William Rojas , Carlos Reverend L. , Lilian Torres , Gloria Quintero   +4 more
doaj   +1 more source

Tratamiento del síndrome de sufrimiento del mediano en el tunel carpiano [PDF]

, 1958
En 3 de los 8 casos se llevó a cabo la intervención quirúrgica: la carnicera, una costurera y el lechero acromegálico (en ambos dedos). Exponemos con detalle la técnica empleada.
Barraquer-Bordas, L. (L.), Cañadell, J.M. (J. M.)   +1 more
core  

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno, Nancy Muriel Herrera Leaño, María Juliana Soto Chávez, Darío Parra Prieto, Alejandro Mariño Correa   +4 more
wiley   +1 more source

Perda auditiva sensorioneural em pacientes com acromegalia em tratamento Sensorineural hearing loss in acromegalic patients under treatment

Brazilian Journal of Otorhinolaryngology, 2012
Acromegalia é uma doença endócrina rara. Poucos estudos avaliaram sua associação com deficiência auditiva (DA) e os resultados são conflitantes. OBJETIVOS: Avaliar a prevalência e características da DA em um grupo de pacientes com acromegalia em ...
Marcelo Alexandre Carvalho, Renan Magalhães Montenegro Júnior, Marcos Rabelo de Freitas, Lúcio Vilar, Alessandra Teixeira Bezerra de Mendonça, Renan Magalhães Montenegro   +5 more
doaj   +1 more source