Results 61 to 70 of about 762 (186)

Luteinizing hormone receptor knockout mouse: What has it taught us?

open access: yesAndrology, Volume 14, Issue 4, Page 1017-1028, May 2026.
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley   +1 more source

A CASE OF ACROMEGALIA ASSOCIATED WITH BRAIN TUMOR [PDF]

open access: yesArchives of Neurology And Psychiatry, 1921
INTRODUCTION The principal interest in this case is the relation between the cerebral tumor and the acromegalic symptoms. To prove which of these was primary or causative is impossible, but we will endeavor to show that the entire picture can be explained on the assumption that the tumor was the original lesion and the polyglandular symptoms were ...
openaire   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1779-1813, May 2026.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos   +16 more
wiley   +1 more source

ACROMEGALIA (MALADIE DE P. MARIE) [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1892
n ...
openaire   +2 more sources

A Case of Heart Failure With Reduced Ejection Fraction Secondary to Dilated Cardiomyopathy due to Long‐Standing Untreated Acromegaly: A Case Report and Focused Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
Echocardiographic findings in dilated cardiomyopathy secondary to untreated acromegaly. (A) Apical four‐chamber view showing biventricular and biatrial dilation. (B‐C) Colour Doppler demonstrating mitral, aortic, and tricuspid regurgitation. (D) Reduced global longitudinal strain (GLS: −6.5%), consistent with severe systolic dysfunction.
Cristian Orlando Porras Bueno   +4 more
wiley   +1 more source

Acromegalia: aspectos diagnósticos e terapêuticos: análise de 18 casos Acromegaly: diagnostic and therapeutic aspects. analysis of 18 cases

open access: yesArquivos de Neuro-Psiquiatria, 1997
Os autores fizeram estudo retrospectivo de 18 pacientes com acromegalia, que foram diagnosticados, tratados e acompanhados pelos Serviços de Endocrinologia e Neurocirurgia do Hospital Universitário Clementino Fraga Filho da Universidade Federal do Rio de
Flávio Freinkel Rodrigues   +3 more
doaj   +1 more source

Hypertensive Urgency and Pulmonary Infiltrates: A Report of Three Cases

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Hypertensive urgency is commonly attributed to medication nonadherence, progression of essential hypertension, or secondary causes. However, in some patients, no clear precipitating factor is identified, despite repeated evaluations and the absence of target organ damage. Subclinical inflammatory conditions have been hypothesized as potential,
Mónica Contreras‐Moreira
wiley   +1 more source

Pycnodysostosis With Papilledema and Isolated Low Parathyroid Hormone Levels in an Eight‐Year‐Old Girl: A Genetically Confirmed Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Pycnodysostosis is a rare autosomal recessive skeletal dysplasia resulting from pathogenic variants in the CTSK gene, which encodes cathepsin K, a lysosomal cysteine protease expressed in osteoclasts. Deficiency of this enzyme leads to defective bone resorption and generalized osteosclerosis.
Meghana Krishna Kesineni   +6 more
wiley   +1 more source

How Effective Is Vitamin C for Gingival Depigmentation? A Scoping Review

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives Excessive gingival pigmentation can be treated by surgically removing the pigmented gingival tissue with a scalpel, bur, LASER, electrocautery, cryotherapy, chemical peeling, or masking with free gingival grafts. Recently, vitamin C (ascorbic acid), in gel, powder, or liquid has been used alone or as an adjunct to micro‐needling or ...
Shubhankar Mehrotra   +4 more
wiley   +1 more source

Acromegalia ectópica por carcinoide bronquial

open access: yesAnales del Sistema Sanitario de Navarra, 2014
Los tumores que causan acromegalia ectópica pueden hacerlo a través de la secreción de GH o de GHRH. Se han descrito un centenar de casos de acromegalia ectópica por secreción de GHRH.
J. Rojo Álvaro   +5 more
doaj  

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