Results 61 to 70 of about 1,043 (197)

Acromegalia em felinos

Pubvet
Acromegaly in felines occurs mainly due to a pituitary adenoma of somatotropic cells, and presents slow and progressive evolution, responsible for increasing the production and secretion of growth hormones (GH). This condition is common in senile or adult male domestic cats, neutered and with short hair.
Bruna Souza Telles, Patrícia Franciscone Mendes   +1 more
openaire   +1 more source

Multiple Machine Learning Algorithms for Predicting Postoperative Residual Tumor in Pituitary Neuroendocrine Tumors

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
An explainable random forest–based machine learning model accurately predicted postoperative residual tumors in PitNETs, with tumor size and Knosp grade as major predictors, offering a web‐based tool for individualized surgical risk assessment and precision management.
Mingrui Li, Chenyang Zhao, Guodong Tang, Yang Li, Qing Liu   +4 more
wiley   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi, Weiwei Chen, Kunhao Chen, Song Yang, Sibo Wang, Tongtian Ni, Dan Xu, Enqiang Mao, Erzhen Chen, Ying Chen   +9 more
wiley   +1 more source

Acromegalia: aspectos diagnósticos e terapêuticos: análise de 18 casos Acromegaly: diagnostic and therapeutic aspects. analysis of 18 cases

Arquivos de Neuro-Psiquiatria, 1997
Os autores fizeram estudo retrospectivo de 18 pacientes com acromegalia, que foram diagnosticados, tratados e acompanhados pelos Serviços de Endocrinologia e Neurocirurgia do Hospital Universitário Clementino Fraga Filho da Universidade Federal do Rio de
Flávio Freinkel Rodrigues, Alice Helena Dutra Violante, José Lourenço Kallás, Mário Vaisman   +3 more
doaj   +1 more source

Acromegalia: uma análise dos impactos em regulações neuroendócrinas [PDF]

A acromegalia é um distúrbio endócrino crônico caracterizado pelo aumento progressivo dos tecidos devido à hipersecreção do hormônio do crescimento (GH) após o fechamento das epífises ósseas, resultando em características fenotípicas distintas, como ...
Duarte , Paulo Henrique da Silva, Silva , Lucas Raphael Scuissato, Queiroz , Ana Cecília Alvarenga, Lopes , Janaína do Vale, Campos , Karen Jacyara   +4 more
core   +1 more source

Hepatocyte Growth Hormone Receptor Ablation Is Associated With Aging Phenotypes and Hepatic Mitochondrial Dysfunction

Aging Cell, Volume 25, Issue 10, October 2026.
Hepatocyte‐specific GHR ablation is associated with hepatic and age‐related pathologies, triggering adipose‐liver crosstalk via elevated circulating GH and subsequent CD36‐dependent hepatic steatosis. This loss impairs STAT5b phosphorylation and enhances PPARγ nuclear activation, upregulating Pdk4 and Cd36 to drive mitochondrial dysfunction and ectopic
Kangkang Yang, Yuli Jian, Fusheng Pang, Ming Ying, Qian Yang, Nian Liu, Shujing Wang, Yingjie Wu   +7 more
wiley   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente, Erica L. T. van den Akker, Metin Cetiner, Karine Clément, Elizabeth Forsythe, Alastair Garfield, Peter Kühnen, Gabriel Ángel Martos‐Moreno, David Meeker, Hermann L. Müller, Hanneke M. van Santen, Julia von Schnurbein, Bérénice Segrestin, Tomohiro Tanaka, Manuel Tena‐Sempere, Martin Wabitsch, Stefanie Zorn, I. Sadaf Farooqi   +17 more
wiley   +1 more source

Using clinical data to predict sleep hypoxemia in patients with acromegaly Utilização de achados clínicos para predizer hipoxemia durante o sono em pacientes com acromegalia

Arquivos de Neuro-Psiquiatria, 2007
Hypoxemia secondary to sleep apnea is commonly seen in patients with acromegaly, and this alteration apparently leads to considerable morbidity and mortality among such patients.
Marcelo Palmeira Rodrigues, Luciana Ansanelli Naves, Luiz Augusto Casulari, César Augusto Melo e Silva, Renata Rodrigues de Araújo, Carlos Alberto de Assis Viegas   +5 more
doaj   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease in Adults With Acromegaly: A Meta‐Analysis of Observational Studies

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims Acromegaly is a chronic, progressive disease characterised by excess growth hormone secretion and elevated circulating insulin‐like growth factor 1 levels. Data on hepatic fat content and liver stiffness in adults with active or controlled acromegaly remain inconsistent.
Alessandro Mantovani, Riccardo Morandin, Elisa Molinaroli, Dario Messetti, Nicoletta Rolli, Matteo Forti, Marta Zoco, Stergios A. Polyzos, Giovanni Targher   +8 more
wiley   +1 more source

Apnea obstructiva del sueño (SAOS) en pacientes con acromegalia

, 2015
Identificar la prevalencia de la apnea obstructiva del sueño (SAOS) en pacientes con ...
Rosales Montoya, María del Pilar
core