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2014
Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic,
Philippe, Chanson +2 more
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Acromegaly is due to excessive production of growth hormone (GH), generally by a pituitary GH-secreting adenoma. Its prevalence is estimated at 40-130 cases per million inhabitants. Acromegaly is characterized by slowly progressive acquired somatic disfigurement (mainly involving the face and extremities) and systemic manifestations. The rheumatologic,
Philippe, Chanson +2 more
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The Lancet, 1970
Abstract Clinical, biochemical, electromyographic, and pathological studies of neuromuscular function were carried out in a group of eleven acromegalics. Mild proximal muscle weakness was present in six cases and serum-levels of creatine phosphokinase were elevated in five.
Mastaglia, F.L., Barwick, D.D., Hall, R.
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Abstract Clinical, biochemical, electromyographic, and pathological studies of neuromuscular function were carried out in a group of eleven acromegalics. Mild proximal muscle weakness was present in six cases and serum-levels of creatine phosphokinase were elevated in five.
Mastaglia, F.L., Barwick, D.D., Hall, R.
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Annals of Internal Medicine, 1981
Excerpt Acromegaly is a chronic disease not to be neglected. In addition to its metabolic abnormalities that are the consequence of excessive growth hormone secretion, neurologic sequelae can be ca...
O H, Pearson, B, Arafah, J, Brodkey
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Excerpt Acromegaly is a chronic disease not to be neglected. In addition to its metabolic abnormalities that are the consequence of excessive growth hormone secretion, neurologic sequelae can be ca...
O H, Pearson, B, Arafah, J, Brodkey
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The Journal of Clinical Endocrinology & Metabolism, 1954
THE occurrence of two normal pregnancies in an acromegalic female afforded an opportunity for a detailed study of this rather unusual relationship. A review of the world literature revealed 33 reported cases of pregnancy occurring in patients with acromegaly.
W A, ABELOVE, J J, RUPP, K E, PASCHKIS
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THE occurrence of two normal pregnancies in an acromegalic female afforded an opportunity for a detailed study of this rather unusual relationship. A review of the world literature revealed 33 reported cases of pregnancy occurring in patients with acromegaly.
W A, ABELOVE, J J, RUPP, K E, PASCHKIS
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Pathophysiology of Acromegaly*
Endocrine Reviews, 1983This review discusses the pathophysiology of acromegaly. Acromegaly has been classified in this paper into distinct entities based on etiology, ultrastructural features of the pituitary, and cytogenesis. This classification has been proposed based on clinical signs, immunoperoxidase techniques, transmission electromicroscopy and immunoelectron ...
S, Melmed +4 more
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British Journal of Psychiatry, 1981
There is only a small literature on the psychiatric complications of acromegaly. Manfred Bleuler (1954) reported an acromegalic man who had blunted affect and apathy and suggested that this clinical picture represented a special variation of the endocrine psychosyndrome. Avery (1973) reported a further case of depression and anxiety in association with
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There is only a small literature on the psychiatric complications of acromegaly. Manfred Bleuler (1954) reported an acromegalic man who had blunted affect and apathy and suggested that this clinical picture represented a special variation of the endocrine psychosyndrome. Avery (1973) reported a further case of depression and anxiety in association with
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Endocrinology and Metabolism Clinics of North America, 1991
Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to ...
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Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to ...
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The American Journal of Medicine, 1960
G J, HAMWI, T G, SKILLMAN, K C, TUFTS
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G J, HAMWI, T G, SKILLMAN, K C, TUFTS
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